Refining the rat sciatic nerve block: a novel ultrasound-guided technique

Murine translational models are an important tool to understand pain pathophysiology. One procedure used frequently in murine research is the sciatic nerve block. This study sought to demonstrate the use of ultrasound-guided sciatic nerve block in a cadaveric murine model. A total of 40 injections were performed in 20 Sprague–Dawley male 18-month-old rat cadavers. Necropsy was performed to identify staining of the sciatic nerve. Staining with methylene blue occurred in 40 of 40 ultrasound-guided injections. The extremely accurate nature of this block under ultrasound guidance is favorable for future translational studies in rats undergoing sciatic nerve blocks. This method may represent a significant improvement in current methods.

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Ultrasound-Guided Nerve Blocks (3)Practice of Lower Extremity Nerve Blocks - II :Sciatic Nerve Block

THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA ◽

10.2199/jjsca.33.606 ◽

2013 ◽

Vol 33 (4) ◽

pp. 606-611

Author(s):

Yasuhiro MORIMOTO

Keyword(s):

Sciatic Nerve ◽

Lower Extremity ◽

Nerve Block ◽

Sciatic Nerve Block ◽

Ultrasound Guided ◽

Nerve Blocks

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Ultrasound-guided psoas compartment and sciatic nerve blocks for pain management of hind limb procedures in the alpaca (Vicugna pacos)

Open Veterinary Journal ◽

10.4314/ovj.v10i2.1 ◽

2020 ◽

Vol 10 (2) ◽

pp. 120-127

Author(s):

Andrew Foster

Keyword(s):

Sciatic Nerve ◽

General Anesthesia ◽

Nerve Block ◽

Femoral Nerve ◽

Standing Position ◽

Sciatic Nerve Block ◽

Anesthetic Techniques ◽

Ultrasound Guided ◽

Nerve Blocks ◽

Vicugna Pacos

Background: Loco-regional anesthetic techniques are considered important in the multimodal approach to analgesia in both human and veterinary medicine. No such techniques are described in the alpaca, bar the use of epidural. This is in part due to the lack of anatomical description for this species. While this limitation exists, the use of ultrasound guidance makes peripheral nerve blocks a viable possibility in the alpaca.Case description: A 12-month-old alpaca was referred for the treatment of a septic left tarso-crural joint. Due to a poor prognosis, amputation of the limb under general anesthesia was performed. Sciatic and psoas compartment blocks were attempted with the ultrasound-guided injection of ropivacaine prior to the start of the procedure. While the femoral nerve was possible to visualize, no obturator nerve was identified. A 5-year old alpaca was also referred for a left hind lateral claw removal, due to a squamous cell carcinoma. The sciatic nerve block was performed prior to the claw amputation under general anesthesia. No changes in heart and respiratory rate, or blood pressure suggestive of nociception, were observed in either of these cases. At the end of both the procedures, the patients experienced uneventful recoveries characterized by the ability to maintain the standing position, interest in food, and normal behavior.Conclusion: This report identifies the ease of performance and the challenges encountered using the ultrasound guided psoas compartment and sciatic nerve blocks in the alpaca. It is our hope that this report encourages the use of ultrasound-guided loco-regional techniques in this species. Keywords: Alpaca, Loco-regional anesthesia, Psoas compartment block, Sciatic nerve block, Ultrasound-guided.

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Faculty Opinions recommendation of Ultrasound-guided anterior approach to sciatic nerve block: a comparison with the posterior approach.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1160182.620475 ◽

2009 ◽

Author(s):

Vincent Chan ◽

Ki Jinn Chin ◽

Anahi Perlas

Keyword(s):

Sciatic Nerve ◽

Nerve Block ◽

Anterior Approach ◽

Posterior Approach ◽

Sciatic Nerve Block ◽

Ultrasound Guided

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Ultrasound Guidance Improves the Success of Sciatic Nerve Block at the Popliteal Fossa

Regional Anesthesia and Pain Medicine ◽

10.1016/j.rapm.2007.10.010 ◽

2008 ◽

Vol 33 (3) ◽

pp. 259-265 ◽

Cited By ~ 7

Author(s):

A PERLAS ◽

R BRULL ◽

V CHAN ◽

C MCCARTNEY ◽

A NUICA ◽

...

Keyword(s):

Sciatic Nerve ◽

Nerve Block ◽

Ultrasound Guidance ◽

Popliteal Fossa ◽

Sciatic Nerve Block

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Ultrasound-Guided Midthigh Sciatic Nerve Block—A Clinical and Anatomical Study

Regional Anesthesia and Pain Medicine ◽

10.1097/00115550-200807000-00015 ◽

2008 ◽

Vol 33 (4) ◽

pp. 369-376 ◽

Cited By ~ 23

Author(s):

Michael J. Barrington ◽

Su-Ling K. Lai ◽

Chris A. Briggs ◽

Jason J. Ivanusic ◽

Samuel R. Gledhill

Keyword(s):

Sciatic Nerve ◽

Nerve Block ◽

Anatomical Study ◽

Sciatic Nerve Block ◽

Ultrasound Guided

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Ultrasound-guided popliteal sciatic nerve block using a pocket-sized ultrasound machine: preliminary evidence

British Journal of Anaesthesia ◽

10.1093/bja/aeu462 ◽

2015 ◽

Vol 114 (2) ◽

pp. 336-337 ◽

Cited By ~ 1

Author(s):

T. Saranteas ◽

F. Zafiropoulou ◽

G. Kostopanagiotou ◽

T. Paraskevopoulos

Keyword(s):

Sciatic Nerve ◽

Nerve Block ◽

Preliminary Evidence ◽

Sciatic Nerve Block ◽

Ultrasound Guided ◽

Ultrasound Machine

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Intraneural Ultrasound-guided Sciatic Nerve Block

Anesthesiology ◽

10.1097/aln.0000000000002254 ◽

2018 ◽

Vol 129 (2) ◽

pp. 241-248 ◽

Cited By ~ 11

Author(s):

Gianluca Cappelleri ◽

Andrea Luigi Ambrosoli ◽

Marco Gemma ◽

Valeria Libera Eva Cedrati ◽

Federico Bizzarri ◽

...

Keyword(s):

Sciatic Nerve ◽

Nerve Block ◽

Local Anesthetic ◽

Sciatic Nerve Block ◽

Effective Volume ◽

Ultrasound Guided ◽

Biased Coin Design ◽

Patient Reported ◽

Sensory Motor

Abstract What We Already Know about This Topic What This Article Tells Us That Is New Background Both extra- and intraneural sciatic injection resulted in significant axonal nerve damage. This study aimed to establish the minimum effective volume of intraneural ropivacaine 1% for complete sensory-motor sciatic nerve block in 90% of patients, and related electrophysiologic variations. Methods Forty-seven consecutive American Society of Anesthesiologists physical status I-II patients received an ultrasound-guided popliteal intraneural nerve block following the up-and-down biased coin design. The starting volume was 15 ml. Baseline, 5-week, and 6-month electrophysiologic tests were performed. Amplitude, latency, and velocity were evaluated. A follow-up telephone call at 6 months was also performed. Results The minimum effective volume of ropivacaine 1% in 90% of patients for complete sensory-motor sciatic nerve block resulted in 6.6 ml (95% CI, 6.4 to 6.7) with an onset time of 19 ± 12 min. Success rate was 98%. Baseline amplitude of action potential (mV) at ankle, fibula, malleolus, and popliteus were 8.4 ± 2.3, 7.1 ± 2.0, 15.4 ± 6.5, and 11.7 ± 5.1 respectively. They were significantly reduced at the fifth week (4.3 ± 2.1, 3.5 ± 1.8, 6.9 ± 3.7, and 5.2 ± 3.0) and at the sixth month (5.9 ± 2.3, 5.1 ± 2.1, 10.3 ± 4.0, and 7.5 ± 2.7) (P < 0.001 in all cases). Latency and velocity did not change from the baseline. No patient reported neurologic symptoms at 6-month follow-up. Conclusions The intraneural ultrasound-guided popliteal local anesthetic injection significantly reduces the local anesthetic dose to achieve an effective sensory-motor block, decreasing the risk of systemic toxicity. Persistent electrophysiologic changes suggest possible axonal damage that will require further investigation.

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