Predictors of prolonged hospitalisation and mortality among children admitted with blackwater fever in eastern Uganda

2021 ◽  
pp. 004947552110467
Author(s):  
George Paasi ◽  
Carolyne Ndila ◽  
Francis Okello ◽  
Peter Olupot-Olupot

Our study aimed at determining clinical factors associated with prolonged hospitalisation and death among children admitted with blackwater fever (BWF). We analysed 920 eligible records for the period January – December 2018 from Mbale and Soroti Regional Referral Hospitals in Eastern Uganda. The median hospitalisation was 3 (IQR: 2–5 days) days. Prolonged hospitalisation was in 251/920 (27.3%). Clinical features independently associated with prolonged hospitalisation included abdominal tenderness, body pain and mild fever. 29/920 (3.2%) died, of these 20 (69.0%) within 48 h of admission. Features of severity associated with mortality were noisy or interrupted breathing, tachypnoea, chest pain, convulsions, delayed capillary refill time (≥3 s), severe pallor, high fever (>38.5°C), altered level of consciousness, prostration and acidotic breathing.

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Syed F Ali ◽  
Nabeel Chauhan ◽  
Archana Hinduja

Introduction: Hospice is an option in providing terminally ill patients with good quality end of life care. We sought to determine demographic and clinical factors associated with discharge to hospice in acute ischemic stroke (AIS) patients. Methods: Using our institutional GWTG database, we analyzed 2,363 consecutive AIS patients who were alive at the time of discharge, from Jan 2009 till July 2015. Univariate and multivariable analysis was performed to determine factors associated with discharge to hospice. Results: Out of 2,363 AIS patients, 100 (4.2%) were discharged to hospice care. Patients discharged to hospice care were more likely to be older, Caucasian and less likely to be African American. They more often had Medicare or private insurance, while less likely paid for the care themselves. Patients discharged to hospice more often had atrial fibrillation and heart failure, while less often had diabetes mellitus or were smoker. Altered level of consciousness at presentation was more often in patients discharged to hospice. Although the rates of thrombolysis and pneumonia were similar, UTI was more common in patients discharged to hospice. Thirty-seven percent of patients were made comfort measure prior to discharging them to hospice (Table). On multivariable analysis, older age [OR 1.04 (95% CI 1.01 - 1.07); p<0.001], higher NIHSS [OR 1.15 (95% CI 1.10 - 1.20); p<0.001] and altered level of consciousness at presentation [OR 2.42 (95% CI 1.29 - 4.55); p<0.001] were significantly associated with discharge to hospice care. Conclusion: The rates of discharge to hospice following AIS have substantially grown in the past decade and at our institution 4.2% were discharged to hospice. These patients were older, had higher median NIHSS and more often had altered level of consciousness upon presentation. Large, multicenter studies are needed to address the variation in the rates of hospice care across the United States.


Author(s):  
Alessandra Bandera ◽  
Alessandro Nobili ◽  
Mauro Tettamanti ◽  
Sergio Harari ◽  
Silvano Bosari ◽  
...  

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