scholarly journals Auditory Steady-State Response Audiometry in Profound SNHL: The Impact of Abnormal Middle Ear Function

2005 ◽  
Vol 84 (5) ◽  
pp. 282-288 ◽  
Author(s):  
Ross Tonini ◽  
Charles Ballay ◽  
Spiros Manolidis

Auditory steady-state response (ASSR) audiometry is a commercially available tool that is used to predict behavioral auditory threshold levels. Its particular value stems from the technology's ability to measure frequency-specific responses in the background electroencephalogram to auditory stimuli presented across a broad range of frequencies and sound pressure levels. It is clearly of benefit when used to assess threshold levels in infants and children with severe-to-profound hearing impairment (i. e., cochlear implant candidates). Although numerous authors have provided evidence of the usefulness of ASSR testing, their reports have concerned patients whose middle ear impedance measures were normal. We report the cases of 2 patients who, following improvement of abnormal middle ear impedance values, experienced a marked improvement in measurable thresholds by ASSR testing.

2010 ◽  
Vol 31 (9) ◽  
pp. 1365-1368 ◽  
Author(s):  
Veronique J. O. Verhaegen ◽  
Jef J. S. Mulder ◽  
John F. P. Noten ◽  
Bart M. A. Luijten ◽  
Cor W. R. J. Cremers ◽  
...  

2019 ◽  
Vol 9 (8) ◽  
pp. 203 ◽  
Author(s):  
Motomura ◽  
Inui ◽  
Kawano ◽  
Nishihara ◽  
Okada

The auditory steady-state response (ASSR) elicited by a periodic sound stimulus is a neural oscillation recorded by magnetoencephalography (MEG), which is phase-locked to the repeated sound stimuli. This ASSR phase alternates after an abrupt change in the feature of a periodic sound stimulus and returns to its steady-state value. An abrupt change also elicits a MEG component peaking at approximately 100–180 ms (called “Change-N1m”). We investigated whether both the ASSR phase deviation and Change-N1m were affected by the magnitude of change in sound pressure. The ASSR and Change-N1m to 40 Hz click-trains (1000 ms duration, 70 dB), with and without an abrupt change (± 5, ± 10, or ± 15 dB) were recorded in ten healthy subjects. We used the source strength waveforms obtained by a two-dipole model for measurement of the ASSR phase deviation and Change-N1m values (peak amplitude and latency). As the magnitude of change increased, Change-N1m increased in amplitude and decreased in latency. Similarly, ASSR phase deviation depended on the magnitude of sound-pressure change. Thus, we suspect that both Change-N1m and the ASSR phase deviation reflect the sensitivity of the brain’s neural change-detection system.


2017 ◽  
Vol 31 (3) ◽  
pp. 419-429 ◽  
Author(s):  
Sigita Melynyte ◽  
Evaldas Pipinis ◽  
Vaida Genyte ◽  
Aleksandras Voicikas ◽  
Tonia Rihs ◽  
...  

2002 ◽  
Vol 13 (04) ◽  
pp. 173-187 ◽  
Author(s):  
Barbara Cone-Wesson ◽  
Richard C. Dowell ◽  
Dani Tomlin ◽  
Gary Rance ◽  
Wu Jia Ming

Two studies are reported in which the threshold estimates from auditory steady-state response (ASSR) tests are compared to those of click- or toneburst-evoked auditory brainstem responses (ABRs). The first, a retrospective review of 51 cases, demonstrated that both the click-evoked ABR and the ASSR threshold estimates in infants and children could be used to predict the pure-tone threshold. The second, a prospective study of normal-hearing adults, provided evidence that the toneburst-evoked ABR and the modulated tone–evoked ASSR thresholds were similar when both were detected with an automatic detection algorithm and that threshold estimates varied with frequency, stimulus rate, and detection method. The lowest thresholds were obtained with visual detection of the ABA. The studies illustrate that ASSRs can be used to estimate pure-tone threshold in infants and children at risk for hearing loss and also in normal-hearing adults.


2002 ◽  
Vol 13 (05) ◽  
pp. 260-269 ◽  
Author(s):  
Barbara Cone-Wesson ◽  
John Parker ◽  
Nina Swiderski ◽  
Field Rickards

Two studies were aimed at developing the auditory steady-state response (ASSR) for universal newborn hearing screening. First, neonates who had passed auditory brainstem response, transient evoked otoacoustic emission, and distortion-product otoacoustic emission tests were also tested with ASSRs using modulated tones that varied in frequency and level. Pass rates were highest (> 90%) for amplitude-modulated tones presented at levels ≥ 69 dB SPL. The effect of modulation frequency on ASSR for 500- and 2000-Hz tones was evaluated in full-term and premature infants in the second study. Full-term infants had higher pass rates for 2000-Hz tones amplitude modulated at 74 to 106 Hz compared with pass rates for a 500-Hz tone modulated at 58 to 90 Hz. Premature infants had lower pass rates than full-term infants for both carrier frequencies. Systematic investigation of ASSR threshold and the effect of modulation frequency in neonates is needed to adapt the technique for screening.


2020 ◽  
pp. 155005942098270
Author(s):  
Sarah Ahmed ◽  
Jennifer R. Lepock ◽  
Romina Mizrahi ◽  
R. Michael Bagby ◽  
Cory J. Gerritsen ◽  
...  

Aim Deficits in synchronous, gamma-frequency neural oscillations may contribute to schizophrenia patients’ real-world functional impairment and can be measured electroencephalographically using the auditory steady-state response (ASSR). Gamma ASSR deficits have been reported in schizophrenia patients and individuals at clinical high risk (CHR) for developing psychosis. We hypothesized that, in CHR patients, gamma ASSR would correlate with real-world functioning, consistent with a role for gamma synchrony deficits in functional impairment. Methods A total of 35 CHR patients rated on Global Functioning: Social and Role scales had EEG recorded while listening to 1-ms, 93-dB clicks presented at 40 Hz in 500-ms trains, in response to which 40-Hz evoked power and intertrial phase-locking factor (PLF) were measured. Results In CHR patients, lower 40-Hz PLF correlated with lower social functioning. Conclusions Gamma synchrony deficits may be a biomarker of real-world impairment at early stages of the schizophrenia disease trajectory.


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