scholarly journals Ulcerative Warthin Tumor: A Case Report and Review of the Literature

2020 ◽  
pp. 014556132095757
Author(s):  
Chuan-Jen Hung ◽  
Bor-Hwang Kang ◽  
Jyh-Seng Wang ◽  
Yaoh-Shiang Lin
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Neck Mass ◽  
Histopathological Diagnosis ◽  
Warthin Tumor ◽  
Superficial Parotidectomy ◽  
Fine Needle ◽  
One Year ◽  
The Right ◽  
Surrounding Skin

Warthin tumor with ulceration of the surrounding skin is extremely rare, making it difficult to differentiate from parotid cancer in the clinical setting. We report a 65-year-old man with a Warthin tumor in the right parotid gland that had ulceration of the overlying skin. The patient presented with right upper neck mass 2 years ago. Ultrasound and fine needle aspiration were done, and Warthin tumor was suspected. One year later, the mass was enlarged with ulceration of the skin. Superficial parotidectomy with fusiform excision of the skin was performed, and histopathological diagnosis revealed a Warthin tumor with inflammatory change. We proposed that this unique manifestation may have been induced by fine needle aspiration, enlargement of the tumor, and ischemic changes secondary to pulmonary arteriovenous malformations.

scholarly journals Sebaceous lymphadenoma requiring superficial parotidectomy

2018 ◽  
Vol 11 (1) ◽  
pp. e224975
Author(s):  
Luona Sun ◽  
Roger Chen Zhu ◽  
Jiankun Tong ◽  
Larry Shemen
Keyword(s):  
Parotid Gland ◽  
Lymphoproliferative Disorder ◽  
Needle Aspiration ◽  
Neck Mass ◽  
Incisional Biopsy ◽  
Superficial Parotidectomy ◽  
Fine Needle ◽  
Level Ii ◽  
The Right ◽  
Sebaceous Lymphadenoma

An 82-year-old woman presented with a painless, progressively enlarging right neck mass of 2 years’ duration. CT with contrast showed a 5.0 cm confluence of nodes just inferior to the right parotid gland. Fine-needle aspiration showed a lymphoproliferative disorder. Incisional biopsy showed sebaceous lymphadenoma. She subsequently underwent superficial right parotidectomy with neck dissection of level II-V (performed for enlarged lymph nodes causing significant pain). Facial nerve was preserved. She remained free of disease nearly 1 year postoperatively.

Cell Block and Its Impact in the Diagnosis of Jaw Lesions over Fine Needle Aspiration Cytology

2021 ◽  
pp. 1-7
Author(s):  
Kaveri Hallikeri ◽  
Biji Babu ◽  
Archana Sudhakaran ◽  
Roshni Monteiro
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Dentigerous Cyst ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Cell Block ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Dentigerous Cysts ◽  
Needle Aspiration Cytology

<b><i>Objectives:</i></b> To determine the role and efficacy of fine needle aspiration cytology (FNAC) and cell block in diagnosis of jaw lesions and compare the agreement between FNAC and cell block to predict the diagnosis. <b><i>Method:</i></b> The sample comprised 51 cases, including 12 odontogenic keratocysts (OKCs), 8 ameloblastomas, 22 radicular cysts, 7 dentigerous cysts, and 1 each of intraosseous mucoepidermoid carcinoma (MEC) and adenomatoid odontogenic tumor (AOT). FNAC samples remaining after hematoxylin and eosin (H&amp;E)-stained cytosmear diagnosis were centrifuged at 3,000 rpm for 10 min. The supernatant was discarded and sediment mixed with 2–3 mL alcohol and filtered. To this, 10% formalin was added, filtered, taken for routine processing, and stained with H&amp;E. The result of FNAC smear and cell block was compared with histopathological diagnosis. <b><i>Results:</i></b> On cytological examination of the smears, 7 OKCs and 22 radicular cysts were diagnosed, whereas ameloblastomas, AOT, intraosseous MEC, and dentigerous cysts were not. This gave an agreement of 56.8% with the biopsy reports. Cell block sections stained with H&amp;E of 12 OKCs, 22 radicular cysts, 1 MEC, and 3 cases of ameloblastoma offered a diagnosis in accordance with the biopsies giving an agreement of 74.5%, while dentigerous cyst and AOT failed to do so. In comparison with FNAC, additionally 5 cases of OKC and 1 of MEC could be detected, and in ameloblastoma, out of 8 cases, only 3 yielded a concordant diagnosis through the cell block technique. <b><i>Conclusion:</i></b> In comparison with FNAC, the architectural pattern and the morphology of the cells were better preserved by the cell block technique. This substantiates that cell block could be used as an ancillary technique to aid in definitive diagnosis of head and neck swellings.

BRAF V600E as an accurate marker to complement fine needle aspiration (FNA) cytology in the guidance of thyroid surgery in the Chinese population: evidence from over 1000 consecutive FNAs with follow-up

2020 ◽  
Author(s):  
Qunzi Zhao ◽  
Yong Wang ◽  
Qin Ye ◽  
Ping Wang ◽  
Jianyu Rao
Keyword(s):  
Fine Needle Aspiration ◽  
Thyroid Surgery ◽  
Chinese Population ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Histopathological Diagnosis ◽  
Fine Needle ◽  
Specificity And Sensitivity

Abstract Background Currently, several commercial molecular tests have been developed for reclassifying thyroid nodules with indeterminate fine needle aspiration cytology. These tests are quite expensive and not available in China. Previous studies demonstrated a very high prevalence of the BRAF V600E mutation in Asian people. A high incidence may result in a robust sensitivity. We conducted this study to determine the prevalence of BRAF V600E mutation and its ability to reclassify cytologically indeterminate thyroid nodules in the Chinese population. Methods Between January 2016 and October 2018, consecutive patients who underwent a fine needle aspiration procedure and agreed to provide materials for molecular analysis in our hospital were recruited in this study. All were followed up until they had a thyroidectomy and a final pathological diagnosis or until January 2019 (those did not have surgery). Results A total of 1960 patients were included in this study. Until January 2019, 1240 patients underwent surgery. Using histopathological diagnosis as a gold standard, the overall sensitivity and specificity of the BRAF V600E mutational analysis for the discrimination of benign nodules from cancer in thyroid fine needle aspiration samples were 83.3% (81.0–85.3%) and 96.0% (77.7–99.8%), respectively, with an area under the ROC curve of 0.90 (95% CI 0.85–0.95, P &lt; 0.001). Among cases with indeterminate cytology, BRAF-positive cases were showing malignancy in the final pathology, and BRAF-negative cases were showing safer to be followed up. Conclusion The BRAF V600E mutation is highly prevalent in the Chinese population and can accurately complement cytopathology in the guidance of thyroid surgery. Mini-abstract: The BRAF V600E mutation has both high specificity and sensitivity to predict thyroid malignancy in the Chinese population. It can accurately complement cytopathology in the guidance of thyroid surgery.

scholarly journals Evaluation of Role of Ultra Sound Guided Fine Needle Aspiration Cytology for Diagnosis of Ovarian Lesions with Particular References to Diagnostic Pitfalls

2014 ◽  
Vol 13 (2) ◽  
pp. 158-162
Author(s):  
Sanjay Sengupta ◽  
Rajib Kumar Mondal ◽  
Kingshuk Bose ◽  
Rudranarayan Ray ◽  
Sritanu Jana ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Medical Science ◽  
Needle Aspiration ◽  
Ultra Sound ◽  
Histopathological Diagnosis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Ovarian lesions are quite common among females of all age groups. Ovarian cancers account for 6% of female malignancy. Ultrasonography (USG) can help in proper identification and categorization of these lesions. Fine Needle Aspiration Cytology (FNAC) under USG guidance can be an effective modality for early diagnosis of ovarian masses. Aims And Objectives: To evaluate the role of USG guided FNAC over ovarian space occupying lesions (SOLs) for proper categorization into non-neoplastic, benign & malignant variants and to identify possible underlying causes of cytological misdiagnosis, if any, in comparison to histopathological diagnosis. Materials and Methods: FNAC under USG guidance were performed over one hundred and sixteen cases with radiologically proved ovarian SOLs during a period of five years. Aspirated materials were interpreted as non- neoplastic, benign or malignant lesions. Histopathological study was possible in 47 of these cases. Results: Out of 116 aspirations, non-neoplastic, benign and malignant diagnosis were given in 51, 42 & 23 cases, respectively. During histopathological correlation 41 out of 47 cases (87.2%) show exact cytohistological parity. Rest six cases with cytological misdiagnosis were discussed in detail. Conclusion: USG guided FNAC can effectively diagnose ovarian lesions in more than 87% cases. Scrutiny about failed diagnosis will help to improve accuracy in future. DOI: http://dx.doi.org/10.3329/bjms.v13i2.14520 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.158-162

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