Clinical Studies on Zinc Metabolism during Total Parenteral Nutrition as Related to Zinc Deficiency

1986 ◽  
Vol 10 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Yoji Takagi ◽  
Akira Okada ◽  
Takeo Itakura ◽  
Yasunaru Kawashima
The Lancet ◽  
1977 ◽  
Vol 310 (8028) ◽  
pp. 97-98 ◽  
Author(s):  
B. Messing ◽  
P. Poitras ◽  
J.J. Bernier

1994 ◽  
Vol 40 (11) ◽  
pp. 1160-1162
Author(s):  
Takashi BANDO ◽  
Hitoshi TSUJIMOTO ◽  
Masato OKAMOTO ◽  
Hiroki IGA ◽  
Hideo YOSHIDA ◽  
...  

Author(s):  
Masaharu Nishi ◽  
Hiroo Takehara ◽  
Yoshitaka Kita ◽  
Nobuhiko Komi

PEDIATRICS ◽  
1992 ◽  
Vol 89 (6) ◽  
pp. 1094-1095
Author(s):  
VIKRAM KHOSHOO ◽  
JOHN KJARSGAARD ◽  
BERNICE KRAFCHICK ◽  
STANLEY H. ZLOTKIN

Zinc is an essential trace mineral for all mammals. The activities of many enzymes, including those needed for protein synthesis, are zinc dependent. It is therefore not surprising that zinc deficiency is cinically expressed in rapidly growing tissues. Zinc deficiency commonly presents with specific skin lesions, diarrhea, growth failure, alopecia, irritability, and anorexia. Acquired zinc deficiency is an uncommon entity. It has most often been described in patients receiving total parenteral nutrition with inadequate or no zinc in the nutrient mixture.1,2 It has also been described in breast-fed premature babies3,4 in whom symptoms become apparent by 4 to 5 months of age.


PEDIATRICS ◽  
1982 ◽  
Vol 69 (6) ◽  
pp. 801-803
Author(s):  
Paul A. Palma ◽  
Susan B. Conley ◽  
Sharon S. Crandell ◽  
Susan E. Denson

Total parenteral nutrition has become a mainstay in the management of infants following complicated abdominal surgery. As we have become sophisticated in our understanding of micronutrient nutrition, the term total parenteral nutrition has proved more a goal to be attained than a reality. In an effort to bypass the gastrointestinal tract and nurture critically ill postoperative patients intravenously, a new setting for the manifestation of deficiency states has emerged. This is illustrated by three infants who developed zinc deficiency during postoperative parenteral alimentation despite intravenous zinc supplementation (Fig 1). The pathogenesis of this syndrome and its complications are described, possible etiologies are considered, and recommendations for prevention and therapy are suggested.


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