Thyroplasty Type III to Lower the Vocal Pitch in Trans Men

About 20% of trans men do not achieve cisgender male frequencies (F0≤131 Hz) after gender-affirming hormone treatment (GAHT) with testosterone. The surgical procedure Isshiki thyroplasty type III (TPIII) is described to lower F0, but data on this technique in trans men are lacking. In this study, 8 trans men, unsatisfied with their voice after a minimum of 12 months of GAHT, underwent TPIII to lower F0 at the Department of Head and Neck Surgery at Ghent University Hospital. TPIII was performed by 1 surgeon using the same method each time. Pre- and postoperatively, an acoustic evaluation of the voice took place. The F0 dropped significantly from the preoperative mean of (154.60 ± 12.29) Hz to the postoperative mean of (105.37 ± 10.52) Hz ( t = 9.821, P < .001). TPIII is an effective method for lowering the F0 in trans men who are not satisfied with their voice after long-term GAHT.

Download Full-text

Short‐ and Long‐Term Clinical Skin Effects of Testosterone Treatment in Trans Men

Journal of Sexual Medicine ◽

10.1111/jsm.12366 ◽

2014 ◽

Vol 11 (1) ◽

pp. 222-229 ◽

Cited By ~ 48

Author(s):

Katrien Wierckx ◽

Fleur Van de Peer ◽

Evelien Verhaeghe ◽

David Dedecker ◽

Eva Van Caenegem ◽

...

Keyword(s):

Testosterone Treatment ◽

Trans Men ◽

Short And Long Term ◽

In Trans

Download Full-text

Acoustic evaluation of Isshiki type III thyroplasty for treatment of mutational voice disorders

The Journal of Laryngology & Otology ◽

10.1017/s0022215100143099 ◽

1999 ◽

Vol 113 (1) ◽

pp. 31-34 ◽

Cited By ~ 17

Author(s):

Guo-Dong Li ◽

Liancai Mu ◽

Shilin Yang

Keyword(s):

Fundamental Frequency ◽

Voice Disorders ◽

Normal Value ◽

Type Iii ◽

Acoustic Measures ◽

Acoustic Evaluation ◽

Male Patients ◽

Vocal Intensity ◽

The Voice ◽

Operative Measures

AbstractThe goal of this study was to determine if there are acoustical differences between pre- and post-surgical voices and to evaluate the effectiveness of Isshiki type III thyroplasty in 11 male patients with mutational voice disorders. Acoustic measures were obtained both pre- and post-operatively. A comparison of pre-and post-operative fundamental frequency (Fo), voice frequencies, and vocal intensity obtained from a sustained vowel /i/ during different phonatory tasks was made. The results from the present study demonstrated that after operation the voice frequencies were significantly decreased (p<0.05). The vocal intensity tended to reduce slightly as the voice frequency lowered. However, there were no statistically significant differences in the pre- and post-operative measures of vocal intensity (p>0.5). The preoperative high pitched voices of all the male patients were lowered up to the normal value by the type III thyroplasty.

Download Full-text

Toward a Protocol for Transmasculine Voice: A Service Evaluation of the Voice and Communication Therapy Group Program, Including Long-Term Follow-Up for Trans Men at the London Gender Identity Clinic

Transgender Health ◽

10.1089/trgh.2019.0011 ◽

2019 ◽

Vol 4 (1) ◽

pp. 143-151 ◽

Cited By ~ 4

Author(s):

Matthew Mills ◽

Gillie Stoneham ◽

Skye Davies

Keyword(s):

Gender Identity ◽

Therapy Group ◽

Service Evaluation ◽

Group Program ◽

Trans Men ◽

Long Term Follow Up ◽

The Voice

Download Full-text

Tonsillectomy versus tonsillotomy for recurrent acute tonsillitis in children and adults (TOTO): study protocol for a randomized non-inferiority trial

Trials ◽

10.1186/s13063-021-05434-y ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Orlando Guntinas-Lichius ◽

Katharina Geißler ◽

Thomas Asendorf ◽

Ralf Tostmann ◽

Jan Löhler

Keyword(s):

Young Adults ◽

Surgical Treatment ◽

Meta Analysis ◽

Neck Surgery ◽

German Society ◽

University Hospital ◽

Acute Tonsillitis ◽

Obstructive Sleep ◽

Children And Young Adults

Abstract Background Tonsillectomy is one of the most frequently performed surgeries in children and young adults worldwide. For decades, tonsillectomy was the surgical treatment of choice for recurrent acute tonsillitis. Tonsillotomy was used in some countries as an alternative to tonsillectomy only for the treatment of obstructive sleep apnea in young children. In recent years, an increase of tonsillotomy also to treat recurrent acute tonsillitis can be observed. Therefore, the German Institute for Quality and Efficiency in Health Care (IQWiG) was commissioned by the Federal Joint Committee (G-BA) to investigate whether tonsillotomy offers advantages compared to tonsillectomy. The meta-analysis of the IQWiG including studies until 2016 revealed that the long-term benefits and harms of tonsillotomy compared to tonsillectomy are unclear. Consequently, the G-BA performed a European call for a clinical trial. A consortium of the German Professional Association of ENT-surgeons (BVHNO), the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNO-KHC), and the Jena University Hospital were finally selected to perform the TOTO study. Methods TOTO is a multicenter, 1:1 two-arm, randomized non-blinded non-inferiority trial. Four hundred fifty-four patients ≥ 3 years of age will be randomly allocated to undergo either tonsillotomy or tonsillectomy as surgical treatment of recurrent acute tonsillitis. All participants will be followed up for a total of 24 months. The primary outcome is the number of sore throat days experienced over the 24-month follow-up. Discussion TOTO is designed to evaluate the effectiveness and efficiency of tonsillectomy versus tonsillectomy for the management of patients with recurrent acute tonsillitis. Tonsil disease and surgery have a major impact on preschool and school children as well as on economically active young adults, with individual and societal costs through loss of school visits, earnings, and productivity. If tonsillotomy is at least as effective as tonsillectomy but with reduced morbidity, this would reduce costs to the healthcare system and society. Trial registration German Clinical Trials Register DRKS00020823. Registered on 04 September 2020.

Download Full-text

Breast cancer risk in transgender people receiving hormone treatment: nationwide cohort study in the Netherlands

BMJ ◽

10.1136/bmj.l1652 ◽

2019 ◽

pp. l1652 ◽

Cited By ~ 35

Author(s):

Christel J M de Blok ◽

Chantal M Wiepjes ◽

Nienke M Nota ◽

Klaartje van Engelen ◽

Muriel A Adank ◽

...

Keyword(s):

Breast Cancer ◽

Cohort Study ◽

The Netherlands ◽

Confidence Interval ◽

Invasive Breast Cancer ◽

Hormone Treatment ◽

Transgender People ◽

Trans Men ◽

In Trans ◽

Trans Women

AbstractObjectiveTo investigate the incidence and characteristics of breast cancer in transgender people in the Netherlands compared with the general Dutch population.DesignRetrospective, nationwide cohort study.SettingSpecialised tertiary gender clinic in Amsterdam, the Netherlands.Participants2260 adult trans women (male sex assigned at birth, female gender identity) and 1229 adult trans men (female sex assigned at birth, male gender identity) who received gender affirming hormone treatment.Main outcome measuresIncidence and characteristics (eg, histology, hormone receptor status) of breast cancer in transgender people.ResultsThe total person time in this cohort was 33 991 years for trans women and 14 883 years for trans men. In the 2260 trans women in the cohort, 15 cases of invasive breast cancer were identified (median duration of hormone treatment 18 years, range 7-37 years). This was 46-fold higher than in cisgender men (standardised incidence ratio 46.7, 95% confidence interval 27.2 to 75.4) but lower than in cisgender women (0.3, 0.2 to 0.4). Most tumours were of ductal origin and oestrogen and progesterone receptor positive, and 8.3% were human epidermal growth factor 2 (HER2) positive. In 1229 trans men, four cases of invasive breast cancer were identified (median duration of hormone treatment 15 years, range 2-17 years). This was lower than expected compared with cisgender women (standardised incidence ratio 0.2, 95% confidence interval 0.1 to 0.5).ConclusionsThis study showed an increased risk of breast cancer in trans women compared with cisgender men, and a lower risk in trans men compared with cisgender women. In trans women, the risk of breast cancer increased during a relatively short duration of hormone treatment and the characteristics of the breast cancer resembled a more female pattern. These results suggest that breast cancer screening guidelines for cisgender people are sufficient for transgender people using hormone treatment.

Download Full-text

Faculty Opinions recommendation of Fracture Risk in Trans Women and Trans Men Using Long-Term Gender-Affirming Hormonal Treatment: A Nationwide Cohort Study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.736558774.793566308 ◽

2019 ◽

Author(s):

Micol Rothman

Keyword(s):

Cohort Study ◽

Fracture Risk ◽

Hormonal Treatment ◽

Trans Men ◽

In Trans ◽

Trans Women

Download Full-text

Socio-ecological analysis of trans people’s participation in physical activity and sport

International Review for the Sociology of Sport ◽

10.1177/1012690219887174 ◽

2019 ◽

pp. 101269021988717 ◽

Cited By ~ 1

Author(s):

Elena López-Cañada ◽

José Devís-Devís ◽

Sofía Pereira-García ◽

Víctor Pérez-Samaniego

Keyword(s):

Physical Activity ◽

Hormone Treatment ◽

Structured Interviews ◽

Ecological Analysis ◽

Sports Organizations ◽

Trans Men ◽

Trans People ◽

Body Appearance ◽

In Trans ◽

People’S Attitudes

The purpose of this study is to explore and provide understanding of trans people’s participation in physical activity and sport through the socio-ecological perspective. A total of 43 Spanish trans people (21 trans women, 17 trans men and 5 with ‘other self-identifications’), between 15 and 62 years old, participated in semi-structured interviews. Thematic analysis identified six main themes, which highlight the multidimensional relations between individual, social and environmental factors in trans people’s participation in physical activity and sport. Results reveal that the importance of body appearance for ‘passing’ and the fear of being unmasked affect their participation. Trans people also rely on physical activity and sport to accelerate or avoid the side effects of hormone treatment. Social support from family and close friends and health professionals are essential for engaging in physical activity and sport. Experiences in physical education also influence trans people’s attitudes towards physical activity and sport. Finally, spaces (e.g. swimming pools and changing rooms), legal requirements and lesbian, gay, bisexual and transsexual teams and leagues are also identified as key socio-ecologic themes. These findings are relevant for health and physical activity professionals, educators, sports organizations and policymakers in facilitating trans people’s participation in physical activity and sport and improving promotion strategies.

Download Full-text