Bullous Myringitis with Sensorineural Hearing Loss

Bullous myringitis is manifested by moderately severe otalgia associated with vesicles on the tympanic membrane and medial external auditory canal wall. This disease occurs mainly in young adults, most commonly in winter, and is usually preceded or accompanied by an upper respiratory infection. A reversible sensorineural loss developed in three of 22 patients. Complement fixation antibody studies performed on ten patients failed to implicate Mycoplasma pneumoniae, influenza virus types A or B, or adenovirus as the causal agent.

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Otologic Manifestations of Wegener's Granulomatosis

Otolaryngology ◽

10.1177/019459988008800512 ◽

1980 ◽

Vol 88 (5) ◽

pp. 586-593 ◽

Cited By ~ 65

Author(s):

Thomas V. McCaffrey ◽

Thomas J. McDonald ◽

George W. Facer ◽

Richard A. DeRemee

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Tympanic Membrane ◽

Middle Ear ◽

Wegener’S Granulomatosis ◽

Wegener's Granulomatosis ◽

Tympanic Membrane Perforation ◽

Sensorineural Hearing ◽

Suppurative Otitis Media ◽

Membrane Perforation

Review of 112 patients with Wegener's granulomatosis showed that 21 (19%) had ear involvement. Conductive deafness, which was present in all 21 patients, was due to serous middle ear fluid, suppurative otitis media with thickening of the tympanic membrane, perforation of the tympanic membrane, or granulation tissue in the middle ear space. Nine patients also had sensorineural hearing loss. Sensorineural hearing loss was improved in five of the nine patients after control of the disease with prednisone and cyclophosphamide.

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Radiographic findings in young adults with asymmetric sensorineural hearing loss

American Journal of Otolaryngology ◽

10.1016/j.amjoto.2018.10.003 ◽

2019 ◽

Vol 40 (1) ◽

pp. 78-82

Author(s):

Hiba Z. Khan ◽

Catherine Y. Park ◽

Michelle A. Lim ◽

Amado J. Beltran ◽

Douglas Farquhar ◽

...

Keyword(s):

Young Adults ◽

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

Radiographic Findings ◽

Asymmetric Sensorineural Hearing Loss

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The relationship between influenza and pneumonia

Epidemiology and Infection ◽

10.1017/s0022172400014789 ◽

1949 ◽

Vol 47 (4) ◽

pp. 434-448 ◽

Cited By ~ 18

Author(s):

C. H. Stuart-Harris ◽

Joan Laird ◽

D. A. Tyrrell ◽

Margaret H. Kelsall ◽

Zena C. Franks ◽

...

Keyword(s):

Influenza Virus ◽

Virus Infection ◽

Influenza A ◽

Influenza Virus Infection ◽

Influenza B ◽

Serological Tests ◽

Upper Respiratory Infection ◽

Influenza Virus A ◽

Epidemic Period ◽

Upper Respiratory

1.The results are reported of a study cases of pneumonia, of upper respiratory indection and of family contacts of cases of pneumoia for evidence of influenza-virus infection between October 1947 and April 1949.2. During an inter-epidemic period in relation to influenza, two sporadic cases of influenza-virus A infection were detected, one in a case of pneumo-coccal pneumonia and the other in a family contact of a case of pneumonia. These were the only instances of virus infection detected amoung 158 individuals including seventy-eight cases of pneumonia.3. The epidemic of influenza from February to April 1949 was associated with an increase in number of notified cases of pneumonia, particularly in those over 45 years of age compared with the notifications in 1948. Deaths from pneumonia also increased, particularly in those of 65years or over.4. During the period of influenza prevalence, direct tests of specimens in eggs and serological tests gave positive evidence of influenza prevalence, direct tests of specimens in eggs and serological tests gave positve evidence of influenza virus A infection in many instances. Twenty-six of forty-one cases of upper respiratory infection between February and April 1949 were positive for influenza A and one was a case of influenza B.5. Eifgteen of fifty-five cases of pneumococcal and staphyococcal pneumoniaccal and staphylococcal pneumonia, eight of fifteen cases of bronchitis, one of two cases of bronchiectasis and four of six cases of congestive heart failure gave serological or cultural evidence of influenza virus A infection during the period of February to April 1949.6. The mechanism of influenza-virus infection in relation to bacterial infection of the lower respiratory tract is discussed.

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Study of Epithelial Migration in the Tympanic Membrane and Bony External Auditory Canal Wall in Patients With Irradiated Nasopharyngeal Carcinoma

Otology & Neurotology ◽

10.1097/mao.0000000000000378 ◽

2015 ◽

Vol 36 (2) ◽

pp. 318-322 ◽

Cited By ~ 2

Author(s):

Kalimuthu Santhi ◽

Narayanan Prepageran ◽

Ing Ping Tang ◽

Rajagopalan Raman

Keyword(s):

Nasopharyngeal Carcinoma ◽

Tympanic Membrane ◽

External Auditory Canal ◽

Canal Wall ◽

Epithelial Migration

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Effects of Expansion on Consonant Recognition and Consonant Audibility

Journal of the American Academy of Audiology ◽

10.3766/jaaa.20.2.5 ◽

2009 ◽

Vol 20 (02) ◽

pp. 119-127 ◽

Cited By ~ 2

Author(s):

Marc Brennan ◽

Pamela Souza

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Tympanic Membrane ◽

Research Design ◽

Hearing Aid ◽

Sensorineural Hearing ◽

Low Level ◽

Low Intensity ◽

Consonant Recognition ◽

Speech Token

Background: Hearing aid expansion is intended to reduce the gain for low-level noise. However, expansion can also degrade low-intensity speech. Although it has been suggested that the poorer performance with expansion is due to reduced audibility, this has not been measured directly. Furthermore, previous studies used relatively high expansion kneepoints. Purpose: This study compared the effect of a 30 dB SPL and 50 dB SPL expansion kneepoint on consonant audibility and recognition. Research Design: Eight consonant-vowel syllables were presented at 50, 60, and 71 dB SPL. Recordings near the tympanic membrane were made of each speech token and used to calculate the Aided Audibility Index (AAI). Study Sample: Thirteen subjects with mild to moderate sensorineural hearing loss. Results: Expansion with a high kneepoint resulted in reduced consonant recognition. The AAI correlated significantly with consonant recognition across all conditions and subjects. Conclusion: If consonant recognition is the priority, audibility calculations could be used to determine an optimal expansion kneepoint for a given individual.

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Audiologic and Otologic Clinical Manifestations of Loeys-Dietz Syndrome: A Heritable Connective Tissue Disorder

Otolaryngology ◽

10.1177/01945998211008899 ◽

2021 ◽

pp. 019459982110088

Author(s):

Jun W. Jeon ◽

Julie Christensen ◽

Jennifer Chisholm ◽

Christopher Zalewski ◽

Marjohn Rasooly ◽

...

Keyword(s):

Hearing Loss ◽

Connective Tissue ◽

Sensorineural Hearing Loss ◽

Tympanic Membrane ◽

Conductive Hearing Loss ◽

Wide Spectrum ◽

Clinical Manifestations ◽

Connective Tissue Disorder ◽

Sensorineural Hearing ◽

Conductive Hearing

Objective Loeys-Dietz syndrome (LDS) is a rare genetic connective tissue disorder resulting from TGF-ß signaling pathway defects and characterized by a wide spectrum of aortic aneurysm, arterial tortuosity, and various extravascular abnormalities. This study describes the audiologic, otologic, and craniofacial manifestations of LDS. Study Design Consecutive cross-sectional study. Setting Tertiary medical research institute. Methods Audiologic and clinical evaluations were conducted among 36 patients (mean ± SD age, 24 ± 17 years; 54% female) with genetically confirmed LDS. Cases were categorized into genetically based LDS types 1 to 4 ( TGFBR1, TGFBR2, SMAD3, TGFB2, respectively). Audiometric characteristics included degree and type of hearing loss: subclinical, conductive, mixed, and sensorineural. Results LDS types 1 to 4 included 11, 13, 5, and 7 patients, respectively. In LDS-1, 27% had bilateral conductive hearing loss; 9%, unilateral mixed; and 36%, subclinical. In LDS-2, 38% had conductive hearing loss and 38% subclinical. In LDS-3 and LDS-4, 40% and 43% had bilateral sensorineural hearing loss, respectively. Degree of hearing loss ranged from mild to moderate. Bifid uvula was observed only in LDS-1 (55%) and LDS-2 (62%). Submucosal/hard cleft palates were primarily in LDS-1 and LDS-2. Posttympanostomy tympanic membrane perforations occurred in 45% (10/22 ears) of LDS-1 and LDS-2. There were 4 cases of cholesteatoma: 3 middle ear (LDS-1 and LDS-2) and 1 external ear canal (LDS-3). Conclusion Conductive hearing loss, bifid uvula/cleft palate, and posttympanostomy tympanic membrane perforation are more common in LDS-1 and LDS-2 than LDS-3 and LDS-4, while sensorineural hearing loss was present only in LDS-3 and LDS-4. These LDS-associated key clinical presentations may facilitate an early diagnosis of LDS and thus prompt intervention to prevent related detrimental outcomes.

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Predictors for Sensorineural Hearing Loss in Patients With Tubotympanic Otitis, Cholesteatoma, and Tympanic Membrane Retractions

Otology & Neurotology ◽

10.1097/mao.0b013e318259b885 ◽

2012 ◽

Vol 33 (6) ◽

pp. 934-940 ◽

Cited By ~ 5

Author(s):

Snezana Dragoljub Jesic ◽

Ana Dragan Jotic ◽

Borivoj Bogdan Babic

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Tympanic Membrane ◽

Sensorineural Hearing

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Trends in Use and Timing of Intratympanic Corticosteroid Injections for Sudden Sensorineural Hearing Loss

Otolaryngology ◽

10.1177/0194599820976177 ◽

2020 ◽

pp. 019459982097617

Author(s):

Michael C. Jin ◽

Z. Jason Qian ◽

Shayna P. Cooperman ◽

Jennifer C. Alyono

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Tympanic Membrane ◽

Cox Regression ◽

Sudden Sensorineural Hearing Loss ◽

Hazard Ratio ◽

Sensorineural Hearing ◽

Tympanic Membrane Perforations ◽

Oral Corticosteroids ◽

Corticosteroid Injections

Objective Oral corticosteroids are treatment mainstays for idiopathic sudden sensorineural hearing loss (SSNHL). Recent studies suggest that intratympanic (IT) steroid injections may be effective as an alternate or adjunctive therapy. We sought to investigate nationwide trends in treatment patterns for SSNHL. Study Design Retrospective cross-sectional study. Setting A large nationwide health care claims database spanning 2007 to 2016. Methods Patients with SSNHL were identified from the IBM Watson Health MarketScan Database. Multivariable logistic, linear, and Cox regression were used for demographic- and comorbidity-adjusted analyses. Results Overall, 19,670 patients were included. Between 2007 and 2016, use of oral corticosteroids alone decreased (83.6% to 64.6%, P < .001), while use of IT corticosteroids alone and combination IT-oral corticosteroids increased (IT only, 7.9% to 15.1%, P = .002; IT-oral, 8.5% to 20.4%, P < .001). During the study period, time to treatment initiation decreased for both administration modalities, though more dramatically for IT corticosteroids (IT, 124.0 to 10.6 days, P < .001; oral, 42.6 to 12.7 days, P < .001). In patients receiving both IT and oral corticosteroids, concurrent first-line use increased (25.2% to 52.8%, P < .001). Repeat injections have also become more common but may raise risk of persistent tympanic membrane perforations (vs no injection; hazard ratio [first injection] = 7.95, 95% CI = 5.54-11.42; hazard ratio [fifth or higher injection] = 17.47, 95% CI = 6.93-44.05). Conclusion SSNHL management increasingly involves early IT steroids as an alternative or adjunctive option to oral steroids. Use of repeat IT corticosteroid injections has also increased but may raise risk of persistent tympanic membrane perforations and subsequent tympanoplasty. Future decision analysis and cost-effectiveness studies are necessary to identify an optimal care pattern for SSNHL.

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