Bilateral Electrocochleographic Findings in Unilateral Meniere's Disease

1992 ◽  
Vol 107 (3) ◽  
pp. 370-372 ◽  
Author(s):  
David A. Moffat ◽  
David M. Baguley ◽  
Meredydd Ll Harries ◽  
Marcus Atlas ◽  
Catherine A. Lynch
Keyword(s):  
Endolymphatic Hydrops ◽  
Early Recognition ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Summating Potential ◽  
Unilateral Disease ◽  
Ménière's Disease

At present, electrocochleography is the only proven investigation that can demonstrate objectively the presence of endolymphatic hydrops. The electrophysiologic recordings in response to sound stimuli show an enhancement of the negative summating potential in these cases. It is well established that patients with unilateral Meniere's disease have a high likelihood of development of the disease bilaterally in the fullness of time. Using transtympanic electrocochleography in 40 patients who manifested unilateral clinical Meniere's disease, we have recorded bilateral abnormalities indicative of endolymphatic hydrops in 35% of cases. The early recognition of incipient Meniere's disease in the asymptomatic contralateral ear of a patient with known unilateral disease has obvious profound implications for patient management.

Diagnostic Significance of Transtympanic Electrocochleography in Menière's Disease

1983 ◽  
Vol 92 (2) ◽  
pp. 155-159 ◽  
Author(s):  
W. P. R. Gibson ◽  
D. K. Prasher ◽  
G.P.G. Kilkenny
Keyword(s):  
Endolymphatic Hydrops ◽  
Cell Damage ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Intensity Level ◽  
Menière's Disease ◽  
Summating Potential ◽  
Ménière's Disease

Transtympanic electrocochleography (ECoG) was performed on 32 normal ears, 40 ears affected by hair cell damage without any evidence of endolymphatic hydrops (sensory damage) and 44 ears affected by established Menière's disease. The amplitude of the summating potential (SP) and the amplitude of the action potential (AP) were measured at a click stimulus intensity level of 100 dB HL. The SP amplitude was expressed as a percentage of the AP amplitude. In normal ears, the mean SP/AP ratio was 25% (range 10%-63%). In sensory damage, the SP/AP ratio was 13% (range 0%-29%), and in Menière's ears, the SP/AP ratio was 51% (range 29%-89%). In this series, an SP/AP ratio of 29% provided a diagnostic dividing mark between the sensory damage and Menière's-affected ears. Although this precise division was probably fortuitous, it does suggest that ECoG is a useful tool in the differential diagnosis of these two types of cochlear disorders.

Endolymphatic Mastoid Shunt Surgery in Unilateral Meniere's Disease

1997 ◽  
Vol 76 (9) ◽  
pp. 642-651 ◽  
Author(s):  
David A. Moffat
Keyword(s):  
American Academy ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Complete Control ◽  
Summating Potential ◽  
Ménière's Disease

One-hundred endolymphatic mastoid shunt operations in patients with classic unilateral Meniere's disease were analyzed. The patients were carefully preselected with a comprehensive protocol of audiovestibular and metabolic investigations. All patients had definitive electrophysiologic evidence of endolymphatic hydrops with an enhanced negative summating potential on transtympanic electrocochleography. The surgical results were analyzed both by the original American Academy of Ophthalmology and Otolaryngology Guidelines (AAOO, 1972), and the more recent modifications of the American Academy of Otolaryngology— Head and Neck Surgery (AA-HNS, 1985). Control of vertigo was achieved in 79% of the patients overall, with 42% sustaining complete control and 37% substantial control. A significant hearing improvement was obtained in 15% of cases, there was no change in 56% of patients, and hearing became worse in 29%. Tinnitus improved following surgery in 35% of patients, was the same in 56%, and worse in 9%. Postoperatively, there was no disability in 42% of the patients, some degree of disability in 50%, and severe disability and inability to sustain gainful employment in only 8%.

Electrocochleography in the Evaluation of Patients with Ménière's Disease/Endolymphatic Hydrops

2006 ◽  
Vol 17 (01) ◽  
pp. 045-068 ◽  
Author(s):  
John A. Ferraro ◽  
John D. Durrant
Keyword(s):  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Recording Electrode ◽  
Menière's Disease ◽  
Summating Potential ◽  
Simple Measurement ◽  
Ménière's Disease

Electrocochleography (ECochG) has evolved as an important tool in the diagnosis/assessment/monitoring of Ménière's disease/endolymphatic hydrops (MD/ELH). This manuscript provides an update on the use of ECochG for these purposes. The material presented includes descriptions of the components of the electrocochleogram; ECochG recording approaches and parameters; how to prepare for an exam, including subject/patient considerations; construction and placement of a tympanic membrane recording electrode; and interpretation the electrocochleogram. Various approaches aimed at improving ECochG's sensitivity and specificity to MD/ELH also are described. These approaches go beyond simple measurement of the now-conventional summating potential (SP)/action potential (AP) magnitude ratio to include the SP magnitude to tonebursts, the SP/AP area ratio, and the AP latency difference to clicks of opposing polarity.

Rupture-Like Shrinkage and Regrowth of Endolymphatic Hydrops in Ménière's Disease During Remission

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Munehisa Fukushima ◽  
Yu Suekata ◽  
Takuya Kusumoto ◽  
Shiro Akahani ◽  
Hidehiko Okamoto ◽  
...  
Keyword(s):  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease

Endolymphatic hydrops and therapeutic effects are visualized in ‘atypical’ Meniere's disease

2009 ◽  
Vol 129 (11) ◽  
pp. 1326-1329 ◽  
Author(s):  
Maiko Miyagawa ◽  
Hisakuni Fukuoka ◽  
Keita Tsukada ◽  
Tomohiro Oguchi ◽  
Yutaka Takumi ◽  
...  
Keyword(s):  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Therapeutic Effects ◽  
Menière's Disease ◽  
Ménière's Disease

scholarly journals Endolymphatic Hydrops in Patients With Vestibular Migraine and Concurrent Meniere's Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Sun-Young Oh ◽  
Marianne Dieterich ◽  
Bit Na Lee ◽  
Rainer Boegle ◽  
Jin-Ju Kang ◽  
...  
Keyword(s):  
Inner Ear ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Vestibular Migraine ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Volumetric Quantification ◽  
Ménière's Disease

Objective: Intravenous contrast agent enhanced, high-resolution magnetic resonance imaging of the inner ear (iMRI) confirmed that patients with Menière's disease (MD) and vestibular migraine (VM) could present with endolymphatic hydrops (EH). The present study aimed to investigate EH characteristics and their interrelation to neurotologic testing in patients with VM, MD, or VM with concurrent MD (VM-MD).Methods: Sixty–two patients (45 females, aged 23–81 years) with definite or probable VM (n = 25, 19 definite), MD (n = 29, 17 definite), or showing characteristics of both diseases (n = 8) were included in this study. Diagnostic workup included neurotologic assessments including video-oculography (VOG) during caloric stimulation and head-impulse test (HIT), ocular and cervical vestibular evoked myogenic potentials (o/cVEMP), pure tone audiometry (PTA), as well as iMRI. EH's degree was assessed visually and via volumetric quantification using a probabilistic atlas-based segmentation of the bony labyrinth and volumetric local thresholding (VOLT).Results: Although a relevant number of VM patients reported varying auditory symptoms (13 of 25, 52.0%), EH in VM was only observed twice. In contrast, EH in VM-MD was prevalent (2/8, 25%) and in MD frequent [23/29, 79.3%; χ2(2) = 29.1, p < 0.001, φ = 0.7]. Location and laterality of EH and neurophysiological testing classifications were highly associated (Fisher exact test, p < 0.005). In MD, visual semi-quantitative grading and volumetric quantification correlated highly to each other (rS = 0.8, p < 0.005, two-sided) and to side differences in VOG during caloric irrigation (vestibular EH ipsilateral: rS = 0.6, p < 0.05, two-sided). In VM, correlations were less pronounced. VM-MD assumed an intermediate position between VM and MD.Conclusion: Cochlear and vestibular hydrops can occur in MD and VM patients with auditory symptoms; this suggests inner ear damage irrespective of the diagnosis of MD or VM. The EH grades often correlated with auditory symptoms such as hearing impairment and tinnitus. Further research is required to uncover whether migraine is one causative factor of EH or whether EH in VM patients with auditory symptoms suggests an additional pathology due to MD.

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