Risk Factors for Healing and Recurrence of Chronic Venous Leg Ulcers

2000 ◽  
Vol 15 (2) ◽  
pp. 49-52 ◽  
Author(s):  
J. R. Barwell ◽  
A. S. K. Ghauri ◽  
M. Taylor ◽  
J. Deacon ◽  
C. Wakely ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Leg Ulcer ◽  
Ulcer Recurrence ◽  
Leg Ulcers ◽  
Venous Reflux ◽  
Venous Leg Ulcers ◽  
Duplex Imaging ◽  
Delayed Healing ◽  
Potential Risk Factors

Objective: To identify independent risk factors for delayed healing and increased recurrence of chronic venous leg ulcers. Design: Prospective study. Setting: Community-based leg ulcer service. Patients: Six hundred and thirty-three limbs in 587 consecutive patients with an ankle-brachial pressure index (ABPI) ≥0.85. Method: Potential risk factors were initially assessed in a one-stop clinic incorporating clinical evaluation, ABPI and venous duplex imaging. Limbs were treated within a defined protocol. Twenty-four-week healing and 3-year ulcer recurrence rates were determined. Results: Of 12 potential risk factors age ( p< 0.001), ulcer chronicity ( p< 0.001) and popliteal vein reflux ( p< 0.005) were independent risks for delayed healing. Of 13 potential risk factors rheumatoid arthritis ( p<0.005) and healing time ( p < 0.05) were independent risks for ulcer recurrence. Isolated superficial venous reflux treated by saphenous vein surgery predicted reduced ulcer recurrence ( p< 0.005). Conclusion: Targeting in primary care of ulcer patients with specific characteristics might encourage earlier referral and appropriate resource management. Leg ulcer patients with superficial venous reflux might benefit from surgical correction.

scholarly journals Risk Factors for Delayed Healing and Recurrence of Chronic Venous Leg Ulcers—An Analysis of 1324 Legs

2005 ◽  
Vol 29 (1) ◽  
pp. 74-77 ◽  
Author(s):  
M.S. Gohel ◽  
M. Taylor ◽  
J.J. Earnshaw ◽  
B.P. Heather ◽  
K.R. Poskitt ◽  
...  
Keyword(s):  
Risk Factors ◽  
Leg Ulcers ◽  
Venous Leg Ulcers ◽  
Delayed Healing

Risk factors for delayed healing and long-term recurrence in chronic venous leg ulcers

2000 ◽  
Vol 87 (4) ◽  
pp. 501-501
Author(s):  
J. R. Barwell ◽  
M. Taylor ◽  
A. S. K. Ghauri ◽  
C. Bronder ◽  
L. Phillips ◽  
...  
Keyword(s):  
Risk Factors ◽  
Leg Ulcers ◽  
Venous Leg Ulcers ◽  
Delayed Healing

scholarly journals Potential Risk Factors for Varicose Veins with Superficial Venous Reflux

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Nazmiye Selçuk Kapısız ◽  
Tülin Uzun Kulaoğlu ◽  
Turgay Fen ◽  
Hasan Fahri Kapısız
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Family History ◽  
Rheumatoid Factor ◽  
Body Mass ◽  
Patient Group ◽  
Potential Risk ◽  
Varicose Veins ◽  
Venous Reflux ◽  
Potential Risk Factors

The objective of the study is to evaluate a range of potential risk factors in the etiology of varicose veins with superficial venous reflux. Forty-nine patients attending a cardiovascular surgery clinic for the management of varicose disease between 2009 and 2010 were enrolled for the study. The age range of the patient group was 44,04 ± 15,05 years and female/male (F/M) ratio was 30/19. Twenty-six normal, healthy volunteers with the age of 40,94 ± 13,60 years and with the female/male ratio of 15/11 acted as control subjects. We investigated several parameters including body mass index, age, birth number > 1, standing for a long time (standing for 8 or more hours without taking a break), systemic diseases, family history, venous Doppler fındings, the levels of homocysteine, ferritin, vitamin B12, and hemoglobin, sedimentation rate, mean corpuscular volume, low density lipoprotein, and rheumatoid factor of the patient group and the control group. We also determined the contribution of the methylene tetrahydrofolate reductase 677 C>T and 1298 A>C gene polymorphisms and FV Leiden in both groups. In this small study, there appears to be no association between varicose veins and body mass index, smoking, type 2 DM, hypertension, family history, and birth number. A history of increased standing duration period (>8 hours) and rheumatoid factor positivity have association with varicose veins with superficial venous reflux.

Risk factors for delayed healing in venous leg ulcers: a review of the literature

2015 ◽  
Vol 69 (9) ◽  
pp. 967-977 ◽  
Author(s):  
C. N. Parker ◽  
K. J. Finlayson ◽  
P. Shuter ◽  
H. E. Edwards
Keyword(s):  
Risk Factors ◽  
Leg Ulcers ◽  
Review Of The Literature ◽  
Venous Leg Ulcers ◽  
Delayed Healing

scholarly journals Le ulcere flebostatiche recidive degli arti inferiori: analisi di un’esperienza/Recurrent venous leg ulcers: clinical analysis of an experience

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Alberto Garavello ◽  
Margherita Lo Ponte ◽  
Stefania Gilardi ◽  
Paola Fiamma ◽  
Massimo Tozzi
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Wound Care ◽  
Lower Limbs ◽  
Orthopedic Procedures ◽  
Ulcer Recurrence ◽  
Venous Ulcers ◽  
Potential Risk Factors ◽  
Fattori Di Rischio

Nonostante i recenti progressi in tema di wound care, le ulcere varicose degli arti inferiori restano un problema frequente, con un alto tasso di recidiva. In questo lavoro abbiamo esaminato la storia clinica, la storia chirurgica e le patologie associate di 133 pazienti affetti da ulcera varicosa degli arti inferiori, di cui 56 da ulcera recidiva o plurirecidiva. L’analisi dei fattori di rischio potenziale per recidiva ha evidenziato come la presenza di varici recidive, una pregressa trombosi venosa profonda, problemi ortopedici, interventi ortopedici, l’obesità e un’età inferiore a 60 anni siano fattori di rischio potenziale per una recidiva dell’ulcera. La combinazione di uno più fattori di rischio assume significatività per la possibilità di una recidiva; si passa dal 22,7% in assenza di fattori di rischio al 33% per i pazienti che ne presentano due, fino al 57,5% in presenza di tre fattori di rischio e all’81,3% per quattro o più. L’ulcera varicosa richiede un follow-up stretto del paziente e una terapia elastocompressiva continua, che deve vedere una stretta collaborazione del paziente e un’attenzione specifica ai fattori di rischio. Despite recent advances in wound care, varicose ulcers of lower limbs remain frequent and display a high rate of recurrence. In this paper, we examined the clinical, surgical histories and associated diseases of 133 patients with venous ulcers of the lower limbs, which were recurrent in 56 cases. The analysis of potential risk factors for recurrence showed that the presence of recurrent varicose veins, a previous deep venous thrombosis, orthopedic problems, previous orthopedic procedures, obesity and age lower than 60 are potential risk factors for ulcer recurrence. Furthermore, the association of one or more risk factors increased the likelihood of relapse, from 22.7% with no risk factors to 33% with 2 risk factors, up to 57.5% with 3 risk factors, and up to 81.3% with 4 risk factors or more. Venous ulcers require close follow-up and continuous elastic compression, close collaboration by the patient and specific focus on risk factors.

Risk factors for delayed healing in venous leg ulcers: a review of the literature

2015 ◽  
Vol 69 (9) ◽  
pp. 1029-1030 ◽  
Author(s):  
C. N. Parker ◽  
K. J. Finlayson ◽  
P. Shuter ◽  
H. E. Edwards
Keyword(s):  
Risk Factors ◽  
Leg Ulcers ◽  
Review Of The Literature ◽  
Venous Leg Ulcers ◽  
Delayed Healing

Premature Arterial Disease Associated with Familial Antithrombin III Deficiency

1990 ◽  
Vol 63 (01) ◽  
pp. 013-015 ◽  
Author(s):  
E J Johnson ◽  
C R M Prentice ◽  
L A Parapia
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Potential Risk ◽  
Antithrombin Iii ◽  
Arterial Disease ◽  
Coagulation System ◽  
Early Age ◽  
Arterial Thromboembolism ◽  
Potential Risk Factors ◽  
Antithrombin Iii Deficiency

SummaryAntithrombin III (ATIII) deficiency is one of the few known abnormalities of the coagulation system known to predispose to venous thromboembolism but its relation to arterial disease is not established. We describe two related patients with this disorder, both of whom suffered arterial thrombotic events, at an early age. Both patients had other potential risk factors, though these would normally be considered unlikely to lead to such catastrophic events at such an age. Thrombosis due to ATIII deficiency is potentially preventable, and this diagnosis should be sought more frequently in patients with arterial thromboembolism, particularly if occurring at a young age. In addition, in patients with known ATIII deficiency, other risk factors for arterial disease should be eliminated, if possible. In particular, these patients should be counselled against smoking.

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