scholarly journals Imaging of brain oxygenation with magnetic resonance imaging: A validation with positron emission tomography in the healthy and tumoural brain

2016 ◽  
Vol 37 (7) ◽  
pp. 2584-2597 ◽  
Author(s):  
Samuel Valable ◽  
Aurélien Corroyer-Dulmont ◽  
Ararat Chakhoyan ◽  
Lucile Durand ◽  
Jérôme Toutain ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Magnetic Resonance ◽  
High Sensitivity ◽  
Emission Tomography ◽  
Imaging Biomarker ◽  
C6 Glioma Cells ◽  
Resonance Imaging ◽  
Positron Emission ◽  
The Brain

The partial pressure in oxygen remains challenging to map in the brain. Two main strategies exist to obtain surrogate measures of tissue oxygenation: the tissue saturation studied by magnetic resonance imaging (StO2-MRI) and the identification of hypoxia by a positron emission tomography (PET) biomarker with 3-[18F]fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([18F]-FMISO) as the leading radiopharmaceutical. Nonetheless, a formal validation of StO2-MRI against FMISO-PET has not been performed. The objective of our studies was to compare the two approaches in (a) the normal rat brain when the rats were submitted to hypoxemia; (b) animals implanted with four tumour types differentiated by their oxygenation. Rats were submitted to normoxic and hypoxemic conditions. For the brain tumour experiments, U87-MG, U251-MG, 9L and C6 glioma cells were orthotopically inoculated in rats. For both experiments, StO2-MRI and [18F]-FMISO PET were performed sequentially. Under hypoxemia conditions, StO2-MRI revealed a decrease in oxygen saturation in the brain. Nonetheless, [18F]-FMISO PET, pimonidazole immunohistochemistry and molecular biology were insensitive to hypoxia. Within the context of tumours, StO2-MRI was able to detect hypoxia in the hypoxic models, mimicking [18F]-FMISO PET with high sensitivity/specificity. Altogether, our data clearly support that, in brain pathologies, StO2-MRI could be a robust and specific imaging biomarker to assess hypoxia.

A Review on Brain Imaging Techniques for BCI Applications

2016 ◽  
pp. 39-70
Author(s):  
Saugat Bhattacharyya ◽  
Anwesha Khasnobish ◽  
Poulami Ghosh ◽  
Ankita Mazumder ◽  
D. N. Tibarewala
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Magnetic Resonance ◽  
Brain Imaging ◽  
Near Infrared ◽  
Emission Tomography ◽  
Resonance Imaging ◽  
Functional Near Infrared Spectroscopy ◽  
Positron Emission ◽  
The Brain

Evolution has endowed human race with the most adroit brain, and to harness its potential to the fullest the concept of brain computer interface (BCI) has emerged. One of the most crucial components of BCI is the technique of brain imaging. The first approach in the field of brain imaging was to measure the electrical and magnetic activity of the brain, the techniques being known as Electroencephalography and Magnetoencephalography. Striving for furtherance, researchers came up with another alternative known as Magnetic Resonance Imaging. But it being confined to only structural imaging, the functional aspects of brain were mapped using functional magnetic resonance imaging. A similar but comparatively newer neuroimaging modality is Functional Near Infrared Spectroscopy. Transcranial Magnetic Stimulation neuro-physiological technique is based on the principle of electromagnetic induction. Based on nuclear medicine the brain imaging technologies that are widely explored in the world of BCI are Positron Emission Tomography and Single Positron Emission Tomography.

scholarly journals THE BIGGEST MYSTERIES OF NATURE — THE UNIVERSE AND THE BRAIN

Osvitolohiya ◽  
2020 ◽  
pp. 6-12
Author(s):  
Blashyak Vladislav
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Magnetic Resonance ◽  
Emission Tomography ◽  
Resonance Imaging ◽  
Positron Emission ◽  
The Brain ◽  
The Universe

In the article, which is the result of scientific research in recent decades, the professor points to the value of revolutionary inventions that play a huge role in the development of research, in the evolution of the universe and the brain. One such invention is the telescope. As for the brain, the introduction of research tools such as computed tomography (1972), MRI (magnetic resonance imaging), followed by EEG (electroencephalography), PET (positron emission tomography), MEG (magnetoencephalography) and more recent inventions for tracking of the eyes condition. Such discoveries in science have made the researcher wonder: does knowledge about the brain really allow us to make learning more effective? The scientist provides a classification of children according to their age psychological periods and the work of neurons in the brain. It is indicated that at the age of 4–5 years the network of neurons is best developed. The period of a rebellious teenager is characterized by the maturation of the brain, or the processes of strengthening between neurons. The author speaks about the importance of knowledge in the achievements of neuroeducation in order to understand the strange and most unexpected statements of our students. The article calls for monitoring the results of the latest research on the universe and on our brains. The author is convinced that in the process of teaching educators are able to make certain changes in the brains of their students.

A Review on Brain Imaging Techniques for BCI Applications

2017 ◽  
pp. 300-330 ◽  
Author(s):  
Saugat Bhattacharyya ◽  
Anwesha Khasnobish ◽  
Poulami Ghosh ◽  
Ankita Mazumder ◽  
D. N. Tibarewala
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Magnetic Resonance ◽  
Brain Imaging ◽  
Near Infrared ◽  
Emission Tomography ◽  
Resonance Imaging ◽  
Functional Near Infrared Spectroscopy ◽  
Positron Emission ◽  
The Brain

Evolution has endowed human race with the most adroit brain, and to harness its potential to the fullest the concept of brain computer interface (BCI) has emerged. One of the most crucial components of BCI is the technique of brain imaging. The first approach in the field of brain imaging was to measure the electrical and magnetic activity of the brain, the techniques being known as Electroencephalography and Magnetoencephalography. Striving for furtherance, researchers came up with another alternative known as Magnetic Resonance Imaging. But it being confined to only structural imaging, the functional aspects of brain were mapped using functional magnetic resonance imaging. A similar but comparatively newer neuroimaging modality is Functional Near Infrared Spectroscopy. Transcranial Magnetic Stimulation neuro-physiological technique is based on the principle of electromagnetic induction. Based on nuclear medicine the brain imaging technologies that are widely explored in the world of BCI are Positron Emission Tomography and Single Positron Emission Tomography.

Mind and Image

2015 ◽  
Vol 1 (2) ◽  
Author(s):  
Jean-François Lambert
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Magnetic Resonance ◽  
Emission Tomography ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Contemporary Culture ◽  
Positron Emission ◽  
The Mind ◽  
The Brain

The spectacular improvements in Positron Emission Tomography and Functional Magnetic Resonance Imaging over the last three decades have led researchers to a reconsideration of the brain and the mind. A form of neurophilia has made its way into contemporary culture. The brain is no longer envisaged as an organ a subject possesses, but as an entity with which he identifies, with which he is at one.

scholarly journals Positron Emission Tomography and Magnetic Resonance Imaging of the Brain in Fabry Disease: A Nationwide, Long-Time, Prospective Follow-Up

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0143940 ◽  
Author(s):  
Kirsten Korsholm ◽  
Ulla Feldt-Rasmussen ◽  
Henrik Granqvist ◽  
Liselotte Højgaard ◽  
Birgit Bollinger ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Magnetic Resonance ◽  
Fabry Disease ◽  
Emission Tomography ◽  
Resonance Imaging ◽  
Positron Emission ◽  
Long Time ◽  
The Brain
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