scholarly journals Enhancement of subarachnoid space during magnetic resonance imaging of endolymphatic hydrops: a case report

2021 ◽  
Vol 49 (7) ◽  
pp. 030006052110297
Author(s):  
Milan Vajda ◽  
Jana Dědková ◽  
Maja Stříteská ◽  
Jiří Jandura ◽  
Pavel Ryška

Enhancement of the subarachnoid space after intravenous administration of gadolinium contrast agent is not common. Enhancement usually occurs in pathological conditions that increase the permeability of the blood–cerebrospinal fluid barrier, most notably in meningitis. We herein describe possible subarachnoid enhancement in patients with no apparent effect on the meninges. These patients had clinical signs of Meniere’s disease and underwent specific magnetic resonance imaging of the inner ear to possibly visualize endolymphatic hydrops. The endolymphatic space can be noninvasively imaged by intravenous administration of contrast agent, usually at a double dose, 4 hours before the scanning process. During this time, the contrast agent penetrates not only the perilymph but also the subarachnoid space, where the highest concentration occurs after 4 hours according to some studies.

2007 ◽  
Vol 48 (5) ◽  
pp. 520-530 ◽  
Author(s):  
B. Lundin ◽  
E. Berntorp ◽  
H. Pettersson ◽  
R. Wirestam ◽  
K. Jonsson ◽  
...  

Purpose: To examine the influence of different doses of gadolinium contrast agent on synovial enhancement, to compare magnetic resonance imaging (MRI) findings of synovial hypertrophy and radiographic joint changes in hemophiliacs, and to investigate the value of gadolinium in MRI assessment of synovial hypertrophy in hemophiliacs using dynamic MRI and MRI scoring. Material and Methods: Twenty-one hemophiliacs on prophylactic factor treatment without recent bleeds were subjected to radiography and gadolinium contrast-enhanced dynamic and static MRI of the knee using a standard dose of 0.1 mmol/kg b.w. gadoteridol. In 17 of the patients, the MRI procedure was repeated after a triple dose of gadoteridol. Results: MRI findings of synovial hypertrophy were significantly correlated with Pettersson radiographic scores. In 19 of the 21 MRI investigated joints, administration of contrast agent did not alter the result of the evaluation of synovial hypertrophy. Conclusion: The optimal time interval for volume assessment of synovial hypertrophy after injection of gadolinium contrast agent is dose dependent. Hemophiliacs without recent bleeds have minor to abundant synovial hypertrophy in joints with pronounced radiographic changes. Dynamic MRI is not useful for evaluating hemophilic arthropathy, and gadolinium contrast agent is not routinely indicated for MRI scoring of joints in hemophiliacs.


1992 ◽  
Vol 27 (11) ◽  
pp. 935-940 ◽  
Author(s):  
VLADIMIR S. VEXLER ◽  
YVES BERTHEZÈNE ◽  
CHRISTOPHER L. WOLFE ◽  
RICHARD SIEVERS ◽  
JEAN W. DUPON ◽  
...  

2015 ◽  
Vol 51 (56) ◽  
pp. 11166-11169 ◽  
Author(s):  
Jonathan D. Freedman ◽  
Hrvoje Lusic ◽  
Martin Wiewiorski ◽  
Michelle Farley ◽  
Brian D. Snyder ◽  
...  

A new cationic gadolinium contrast agent is described for imaging articular cartilage.


Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1513
Author(s):  
Fouzi Mouffouk ◽  
Hacene Serrai ◽  
Sourav Bhaduri ◽  
Rik Achten ◽  
Mozhdeh Seyyedhamzeh ◽  
...  

Detecting tissue pH in vivo is extremely vital for medical diagnosis and formulation of treatment decisions. To this end, many investigations have been carried out to develop an accurate and efficient method of in vivo pH measurement. Most of the techniques developed so far suffer from inadequate accuracy, due to poor sensitivity at low concentration of the target or nonspecific interactions within the tissue matrix. To overcome these issues, we describe herein the development of a simple, yet reliable, way to estimate pH with high precision using a Gd(III)-DOTA-silyl-based acid-labile group as a pH-sensitive contrast agent with Magnetic Resonance Imaging (MRI). With this method, a change in T 1 weighted image intensity of the newly developed pH-sensitive contrast is directly linked to the proton concentration in the media. As a result, we were able estimate the pH of the target with 95% reliability.


2015 ◽  
Vol 59 (2) ◽  
pp. 317-319
Author(s):  
Zbigniew Adamiak ◽  
Yauheni Zhalniarovich ◽  
Paulina Przyborowska ◽  
Joanna Głodek ◽  
Adam Przeworski

AbstractThe aim of the study was to identify magnetic resonance imaging (MRI) sequences that contribute to a quick and reliable diagnosis of brachial plexus tumours in dogs. The tumours were successfully diagnosed in 6 dogs by the MRI with the use of SE, FSE, STIR, Turbo 3 D, 3D HYCE, and GE sequences and the gadolinium contrast agent


2017 ◽  
Vol 5 (6) ◽  
pp. 1090-1100 ◽  
Author(s):  
Taofeng Zhu ◽  
Xiuqin Ma ◽  
Ruhua Chen ◽  
Zhijun Ge ◽  
Jun Xu ◽  
...  

The intravenous administration of atta@Fe3O4@Ru nanocomposites to a rabbit model resulted in a marked and negatively enhanced T2-weighted MRI.


Sign in / Sign up

Export Citation Format

Share Document