Meptazinol: A Side-Effect Profile Compared to Placebo in General Practice

1982 ◽  
Vol 10 (4) ◽  
pp. 219-224 ◽  
Author(s):  
R K J Price ◽  
A N Latham
Keyword(s):  
General Practice ◽  
Side Effect ◽  
Intestinal Tract ◽  
Adverse Reactions ◽  
Practice Setting ◽  
Side Effect Profile ◽  
General Practice Setting ◽  
Gastro Intestinal Tract

The side-effect profile of oral meptazinol (200 mg) has been described in comparison to placebo in a multicentre general practice setting. Complaints were concerned primarily with the gastro-intestinal tract (64% and 59% of all reported adverse reactions in the placebo and meptazinol groups, respectively). There was no evidence of any deleterious interaction between meptazinol and other medications taken during the course of the trial.

Acquisition of basic clinical skills in the general practice setting

1997 ◽  
Vol 31 (2) ◽  
pp. 99-104 ◽  
Author(s):  
J V Parle ◽  
S M Greenfield ◽  
J Skelton ◽  
H Lester ◽  
F D R Hobbs
Keyword(s):  
General Practice ◽  
Clinical Skills ◽  
Practice Setting ◽  
General Practice Setting

scholarly journals Suvorexant: A boon for Sleepless Nights

2016 ◽  
Vol 14 (1) ◽  
pp. 43-45
Author(s):  
Anjan Khadka ◽  
Dick Brashier ◽  
Amol Vijay Khanpure ◽  
Pem Chuki
Keyword(s):  
General Practice ◽  
Side Effects ◽  
Side Effect ◽  
Sleep Onset ◽  
Side Effect Profile ◽  
New Class ◽  
Sleep Maintenance ◽  
Nonrestorative Sleep ◽  
Arousal System ◽  
Falling Asleep

Insomnia is characterized by difficulty in falling asleep, difficulty maintaining sleep, or experiencing nonrestorative sleep. Insomnia is the most common medical complaint in general practice.  Low efficacy and various side effects limit the use of existing treatment option. Suvorexant is an orexin receptor antagonist (ORA), first in a new class of drugs in development for the treatment of insomnia. It inhibits the wakefulness-promoting orexin neurons of the arousal system thereby promoting the natural transition from wakefulness. It also improves sleep onset and sleep maintenance and has a favorable tolerability and limited side-effect profile.

scholarly journals Long-Term Effect of Interactive Online Dietician Weight Loss Advice in General Practice (LIVA) Protocol for a Randomized Controlled Trial

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Carl J. Brandt ◽  
Vibeke Brandt ◽  
Mathilde Pedersen ◽  
Dorte Glintborg ◽  
Søren Toubro ◽  
...  
Keyword(s):  
Weight Loss ◽  
General Practice ◽  
Large Scale ◽  
Controlled Trial ◽  
Complex Interventions ◽  
Control Group ◽  
Average Weight ◽  
Practice Setting ◽  
Management Support ◽  
General Practice Setting

Background. Internet-based complex interventions aiming to promote weight loss and optimize healthy behaviors have attracted much attention. However, evidence for effect is lacking. Obesity is a growing problem, resulting in an increasing demand for cost efficient weight loss programs suitable for use on a large scale, for example, as part of standard primary care. In a previous pilot project by Brandt et al. (2011) without a control group, we examined the effects of online dietician counseling and found an average weight loss of 7.0 kg (95% CI: 4.6 to 9.3 kg) after 20 months. Aims and Methods. To analyze the effects of a complex intervention using trained dieticians in a general practice setting combined with internet-based interactive and personalized weight management support compared with conventional advice with a noninteractive internet support as placebo treatment in 340 overweight patients during a 2-year period. Primary endpoints are weight loss and lowering of cholesterol (LDL). We will also explore patients’ sociodemographics and use of the intervention as well as the health professionals’ views and perceptions of the intervention (their role and the advice and support that they provide). Perspective. The project will generate knowledge on the cost-effectiveness of a complex internet-based intervention in a general practice setting and on barriers and acceptability among professionals and patients.

Assessment and management of haematuria in the general practice setting

2021 ◽  
Vol 50 (7) ◽  
pp. 467-471
Author(s):  
Ellen O'Connor ◽  
Aoife McVey ◽  
Stephanie Demkiw ◽  
Nathan Lawrentschuk ◽  
Declan G Murphy
Keyword(s):  
General Practice ◽  
Practice Setting ◽  
General Practice Setting

scholarly journals A depression screening day for the elderly in a general practice setting

1995 ◽  
Vol 19 (4) ◽  
pp. 226-227 ◽  
Author(s):  
Walter Forbes ◽  
Diana E. Tracy ◽  
Ross J. Hamilton ◽  
John M. Eagles
Keyword(s):  
General Practice ◽  
Elderly Population ◽  
The Elderly ◽  
Depression Screening ◽  
Practice Setting ◽  
General Practice Setting ◽  
Symptoms Of Depression ◽  
Elderly Populations

Unrecognised and untreated depression is common, particularly in the elderly. This paper describes an attempt to offer screening for depression to 4,500 people over the age of 60. Only two people attended and both were depressed. This may have related to the arrangements for screening, to the symptoms of depression, to inadequate publicity or to characteristics of the elderly population. Others contemplating screening for depression in elderly populations are advised to adopt a different methodology.

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