The Use of Low Molecular Weight Heparins for Post-Surgical Deep Vein Thrombosis Prevention in Orthopaedic Patients
1988 ◽
Vol 16
(5)
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pp. 359-366
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Keyword(s):
Factor X
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The prophylactic antithrombotic efficacy of a low molecular weight heparin was compared with a traditional unfractionated calcium heparin after orthopaedic surgery in 140 patients. Deep vein thromboses were detected in legs either by Doppler sonography or [125I]fibrinogen uptake tests in five (7.1%) and seven (10%) patients, respectively. The capacity of both drugs to prevent deep vein thrombosis was demonstrated. Compared with the control group, those who used low molecular weight heparin showed a significant increase of activated factor X inhibition and smaller increases in activated partial thromboplastin times. Tolerability of both drugs was good, with a low incidence of local side-effects.
2003 ◽
Vol 29
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pp. 009-012
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1999 ◽
Vol 119
(3-4)
◽
pp. 156-158
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1998 ◽
Vol 79
(05)
◽
pp. 897-901
◽
1993 ◽
Vol 119
(11)
◽
pp. 1105
◽
2019 ◽
Vol 25
◽
pp. 107602961989041
2017 ◽
Vol 3
(3i)
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pp. 585-587