Molecular Cytogenetics and its Applications to Soft Tissue Tumor Analysis

1995 ◽  
Vol 81 (6) ◽  
pp. 395-398 ◽  
Author(s):  
Lucia D'Amato

Cytogenetic analyses have demonstrated the association of specific chromosomal changes with particular types of soft tissue tomors. This work describes the molecular cytogenetic approaches to genetic analysis of these tumors. It illustrates how molecular cytogenetics may provide a rapid and sensitive method of diagnosis and can contribute to identify specific genes implied in the aetiology of soft tissue tumors.

2021 ◽  
Vol 104 (5) ◽  
pp. 728-732

Background: The prevalence and risk factors of venous thromboembolism (VTE) in malignant bone and soft tissue tumor patients that undergo surgery is reported in many studies. However, there is lack of studies on the patients without chemoprophylaxis. Objective: To evaluate the prevalence and risk factors for VTE after surgery in malignant bone and soft tissue tumor patients without chemoprophylaxis Materials and Methods: A retrospective medical chart review identified 260 cases of malignant bone and soft tissue tumor operated between 2008 and 2017. Official diagnostic reports were reviewed from the Picture Archiving and Communication System (PACs). The incidence of VTE and its risk factors were assessed using Chi-square test, t-test, and binary logistic regression. Results: The overall prevalence of symptomatic VTE was 0.8% (2/260 patients), all of which had PE. No fatal VTE was detected. Asymptomatic pulmonary embolism (PE) was identified in two patients (0.8%) Mean follow up interval of the available data was 9.5 (3 to 36) months. No significant risk factor was found. Conclusion: The authors found that patients with malignant bone and soft tissue tumors that underwent surgery without chemoprophylaxis in the authors’ center had lower prevalence of VTE when compared to most previous studies whose patient received chemoprophylaxis. Keywords: Venous thromboembolism, Sarcoma, Cancer, Deep vein thrombosis, Pulmonary embolism, Thromboprophylaxis, Chemoprophylaxis


2005 ◽  
Vol 54 (3) ◽  
pp. 578-581
Author(s):  
Takashi Maekawa ◽  
Toshitake Yakushiji ◽  
Yasuhiro Kawazoe ◽  
Katsuya Iwamoto ◽  
Hiroo Satou ◽  
...  

2016 ◽  
Vol 8 (2) ◽  
pp. 210-213 ◽  
Author(s):  
Abhijeet Ashok Salunke ◽  
Yongsheng Chen ◽  
Victor KM Lee ◽  
Mark Edward Puhaindran

1992 ◽  
Vol 85 (3) ◽  
pp. 317-318 ◽  
Author(s):  
SHAWN A. CHILLAG ◽  
ANTONIO R. CAFONCELLI ◽  
HO-HUANG CHANG ◽  
MILTON J. PLATA ◽  
DAVID ARTZ

1994 ◽  
Vol 31 (5) ◽  
pp. 941
Author(s):  
Sung Moon Lee ◽  
Seong Ku Woo ◽  
Hee Jung Lee ◽  
Mi Young Hwang ◽  
Soo Ji Suh ◽  
...  

2010 ◽  
Vol 17 (2) ◽  
pp. 41-49
Author(s):  
G I Nazarenko ◽  
V Sh Chen ◽  
A N Khitrova

Focused high intensity ultrasound (HIFU) with sighting influence on tumor enabled to cause its complete coagulative necrosis without damage to intact environmental tissues. The possibilities of ultrasound ablation as the method of local treatment of bone and soft-tissue tumor were considered. Physical principles of method, criteria for patient selection, treatment technique as well as clinical outcomes and their evaluation were presented. Advantages of method are non-invasiveness, less traumatization, less technical complexity and dependence on surgeon skill compared with other sparing operations and methods of ablation. When necessary HIFU may be repeated several times. Effect of HIFU is independent on tumor type. Possible complications (secondary infection in coagulative necrosis zone, peripheral nerves damage, pathological fractures) and measures of their prevention are presented.


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