scholarly journals The Systolic Blood Pressure Variation as an Indicator of Pulmonary Capillary Wedge Pressure in Ventilated Patients

1993 ◽  
Vol 21 (4) ◽  
pp. 405-408 ◽  
Author(s):  
P. E. Marik
Keyword(s):  
Data Base ◽  
Pulmonary Capillary Wedge Pressure ◽  
Correlation Coefficient ◽  
Systolic Pressure ◽  
Pressure Variation ◽  
Positive Pressure ◽  
Data Set ◽  
Pulmonary Capillary ◽  
Wedge Pressure ◽  
Ventilated Patients

Animal data have suggested that the systolic pressure variation (SPV) noted during positive pressure ventilation may be a sensitive indicator of hypovolaemia. The aim of this study was to correlate the SPV with the pulmonary capillary wedge pressure (PCWP) in a heterogeneous group of ICU patients on volume-cycled ventilation. Three hundred data sets were collected on 226 patients. The correlation coefficient between the SPV and PCWP for the first half of the data set was - 0.84 (P<0.001). The linear regression formula from this data set was: PCWP = 20- (SPV*0.7). Using this formula the predicted PCWP was then correlated with the measured PCWP using the second half of the data base. The correlation coefficient was 0.87 (P<0.001). The correlation coefficient between the SPV and PCWP for the entire data base (300 observations) was -0.86 (P<0.001). It is concluded that analysis of the arterial pressure tracing may be useful in estimating the pulmonary capillary wedge pressure in ventilated patients.

Lung and myocardial thallium-201 kinetics in resting patients with congestive heart failure: Correlation with pulmonary capillary wedge pressure

1992 ◽  
Vol 123 (2) ◽  
pp. 427-432 ◽  
Author(s):  
Eulogio E. Martinez ◽  
Steven F. Horowitz ◽  
Helio J. Castello ◽  
Mario L.V. Castiglioni ◽  
Antonio C.C. Carvalho ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Pulmonary Capillary Wedge Pressure ◽  
Thallium 201 ◽  
Pulmonary Capillary ◽  
Failure Correlation ◽  
Wedge Pressure

Abstract 11814: Pulmonary Capillary Wedge Pressure as a Strong Predictor for Successful Outcome of Atrial Fibrillation Ablation: A Speckle Tracking Echocardiographic Study

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Mayumi Kaneda ◽  
Masanori Kawasaki ◽  
Takeshi Hirose ◽  
Ryuhei Tanaka ◽  
Rieko Matsuoka ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Pulmonary Capillary Wedge Pressure ◽  
Speckle Tracking ◽  
Filling Pressure ◽  
Successful Outcome ◽  
Af Ablation ◽  
Pulmonary Capillary ◽  
Wedge Pressure ◽  
Recurrence Group

Background: Atrial fibrillation (AF) is associated with left atrial (LA) remodeling caused by LA pressure or volume (LAV) overload represented by the elevated left ventricular filling pressure or LA enlargement. Pulmonary capillary wedge pressure (PCWP) as well as LAV may be useful predictor for successful outcome of AF ablation. The aim of the study was to elucidate the most useful predictor for successful outcome in AF ablation including PCWP measured by a speckle tracking echocardiography (STE). Methods: We measured LAV, LA emptying function (EF), strain and strain rate (SR) by the STE during sinus rhythm before ablation in 137 patients with paroxysmal AF (61±10 years, 80 men) who underwent pulmonary vein isolation. The parameters were compared between non-recurrence (successful) group (n=107, age 61±11, sinus rhythm was continued for more than 1 year) and recurrence group (n=30, age 60±10). The estimated PCWP (ePCWP) was determined as 10.7 - 12.4 x log (active LAEF / minimum LAV), as we previously reported. LA stiffness was calculated as ePCWP/LA strain. We also measured PCWP and LA pressure by cardiac catheterization just before AF ablation in 59 patients. Results: The ePCWP was correlated with PCWP measured by cardiac catheterization (r=0.71, p<0.01). The ePCWP and maximum LAV before ablation in recurrence group increased compared with non-recurrence group (15±3 vs. 11±4 mmHg, and 58±15 vs. 49±15 ml/m2, respectively). LA total and active EF decreased, and LA stiffness increased in recurrence group (39±10 vs. 44±11%, 20±7 vs. 25±10% and 0.83±0.59 vs. 0.47±0.33). In multivariate analysis, ePCWP was independently associated with successful ablation best among LAEF, active EF, maximum LAV and ePCWP. Using 13 mmHg of ePCWP as a cutoff, the sensitivity and specificity for successful ablation were 77 and 73% and the positive and negative predictive value were 44 and 92% (AUC= 0.81). Conclusion: Elevation of ePCWP before AF ablation was the best predictor of AF recurrence after AF ablation. This suggested a strong relation between LV filling pressure and the progression of LA remodeling responsible for AF. The ePCWP estimated by STE is useful to predict the successful outcome of AF ablation.

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