Rebound following oxygen therapy in cluster headache

Cephalalgia ◽  
2011 ◽  
Vol 31 (10) ◽  
pp. 1145-1149 ◽  
Author(s):  
Rianne PJ Geerlings ◽  
Danielle YP Haane ◽  
Peter J Koehler
Keyword(s):  
Cluster Headache ◽  
Oxygen Therapy ◽  
Rebound Effect ◽  
Case Series ◽  
Acute Attack ◽  
Complete Relief ◽  
Headache Attack ◽  
Oxygen Treatment ◽  
Cluster Headache Attack ◽  
The Individual

Background: Rapid recurrence of a new cluster headache attack following oxygen treatment was named the ‘rebound effect’ by Kudrow (1981). It has never been studied properly. To study this effect, we defined it as a more rapid than usual (for the individual patient) recurrent cluster headache attack after complete relief following oxygen therapy, or an increase in the number of attacks per 24 hours while using oxygen therapy as acute attack treatment. We reviewed the literature and searched our cluster headache study databases. Case series: In our eight patients with rebound cluster headache, the effect was experienced following 87.5% of oxygen treated attacks. Duration until the next cluster headache attack was on average 894 minutes shorter and frequency was on average 1.6 cluster headache attacks per day higher than without oxygen therapy. Conclusion: Although the 1981 trial reported a prevalence of 25%, rebound cluster headache following oxygen therapy is rarely reported nowadays. This may be due to better techniques in oxygen application, the use of higher oxygen flow rates or underreporting. The few literature data and data on our eight patients did not provide clues about the mechanism of the rebound effect. Further study, applying the proposed definition, seems useful.

The impact of sexual activity on idiopathic headaches: An observational study

Cephalalgia ◽  
2013 ◽  
Vol 33 (6) ◽  
pp. 384-389 ◽  
Author(s):  
Anke Hambach ◽  
Stefan Evers ◽  
Oliver Summ ◽  
Ingo W Husstedt ◽  
Achim Frese
Keyword(s):  
Observational Study ◽  
Cluster Headache ◽  
Sexual Activity ◽  
Case Reports ◽  
Primary Headache ◽  
Complete Relief ◽  
Headache Attack ◽  
Cluster Headache Attack ◽  
The Impact ◽  
Headache Patients

Background Headache associated with sexual activity is a well-known primary headache disorder. In contrast, some case reports in the literature suggest that sexual activity during a migraine or cluster headache attack might relieve the pain in at least some patients. We performed an observational study among patients of a tertiary headache clinic. Methods A questionnaire was sent to 800 unselected migraine patients and 200 unselected cluster headache patients. We asked for experience with sexual activity during a headache attack and its impact on headache intensity. The survey was strictly and completely anonymous. Results In total, 38% of the migraine patients and 48% of the patients with cluster headache responded. In migraine, 34% of the patients had experience with sexual activity during an attack; out of these patients, 60% reported an improvement of their migraine attack (70% of them reported moderate to complete relief) and 33% reported worsening. In cluster headache, 31% of the patients had experience with sexual activity during an attack; out of these patients, 37% reported an improvement of their cluster headache attack (91% of them reported moderate to complete relief) and 50% reported worsening. Some patients, in particular male migraine patients, even used sexual activity as a therapeutic tool. Conclusions The majority of patients with migraine or cluster headache do not have sexual activity during headache attacks. Our data suggest, however, that sexual activity can lead to partial or complete relief of headache in some migraine and a few cluster headache patients.

Studies of Platelet Monoamine Oxidase Activity during an Acute Cluster Headache Attack.

Cephalalgia ◽  
1991 ◽  
Vol 11 (11_suppl) ◽  
pp. 254-255 ◽  
Author(s):  
Aron D. Mosnaim ◽  
Shankar Huprikar ◽  
Marion E. Wolf ◽  
Frederick Freitag ◽  
Seymour Diamond
Keyword(s):  
Monoamine Oxidase ◽  
Cluster Headache ◽  
Oxidase Activity ◽  
Monoamine Oxidase Activity ◽  
Headache Attack ◽  
Cluster Headache Attack ◽  
Platelet Monoamine Oxidase

scholarly journals Phase Specific Pain Localization in Cluster Headache Patients.

2020 ◽  
Author(s):  
Philipp Schröder ◽  
Charly Gaul ◽  
Attyla Drabik ◽  
Albrecht Molsberger
Keyword(s):  
Cluster Headache ◽  
Online Survey ◽  
Anatomical Structures ◽  
Headache Attack ◽  
Location Data ◽  
Pain Location ◽  
Cluster Headache Attack ◽  
Significant Difference ◽  
Survey Results ◽  
Pain Localization

Abstract Background and Objective:Applying local treatments like neuromodulation or injections for cluster headache, requires exact knowledge of the anatomical structures and pain topography. However studies with emphasis on exact pain localization are rare although local treatments are increasingly used for patients in whom systemic pharmacotherapy is ineffective or contraindicated. Here, survey results with emphasis on exact pain location in cluster headache attacks for onset of pain, peak pain and radiation of pain, are presented. Methods: Data from 631 respondents were collected for 23 months using an online survey composed of 117 questions on pain location, epidemiology, and clinical features. 5260 datapoints on 44 pain locations were analyzed.Results: There is a periorbital concentration of pain during onset and peak phases of attacks. Pain locations outside the periorbital region were reported more frequently during radiation when compared to the onset and peak of attacks. Dorsal (occipital/nuchal) pain is more frequent during onset and radiation compared to peak: onset pain (13%) vs. peak pain (6%), p < 0,001. Pain radiation (22%) vs. peak pain (6%), p < 0,001. There is no significant difference in dorsal pain frequencies for pain radiation (22%) vs. onset (13%), p = 0,552. Furthermore, single pain spots differ significantly in frequency during the three attack phases.Conclusions: Analysis of the pain location data shows phase specific frequencies and distributions of pain location during the three stages of a cluster headache attack. Single pain spots differ significantly in frequency during the three attack phases. Dorsal pain is more frequent during onset and radiation, compared to peak. Extra-orbital pain locations are more frequent during pain radiation. These findings will help to better understand cluster headache and might help to identify further target structures for local treatments.

Beta-oscillations in the posterior hypothalamus are associated with spontaneous cluster headache attack

2010 ◽  
Vol 257 (10) ◽  
pp. 1743-1744 ◽  
Author(s):  
Wido Nager ◽  
Thomas F. Münte ◽  
Josep Marco-Pallares ◽  
Marcus Heldmann ◽  
Reinhard Dengler ◽  
...  
Keyword(s):  
Cluster Headache ◽  
Posterior Hypothalamus ◽  
Beta Oscillations ◽  
Headache Attack ◽  
Cluster Headache Attack

Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack

Pain ◽  
1995 ◽  
Vol 60 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Marcello Fanciullacci ◽  
Massimo Alessandri ◽  
Michela Figini ◽  
Pierangelo Geppetti ◽  
Sergio Michelacci
Keyword(s):  
Cluster Headache ◽  
Calcitonin Gene Related Peptide ◽  
Headache Attack ◽  
Related Peptide ◽  
Cluster Headache Attack ◽  
Calcitonin Gene

Oxygen treatment of cluster headache: A review

Cephalalgia ◽  
2014 ◽  
Vol 34 (13) ◽  
pp. 1079-1087 ◽  
Author(s):  
Anja S Petersen ◽  
Mads CJ Barloese ◽  
Rigmor H Jensen
Keyword(s):  
Cluster Headache ◽  
Hyperbaric Oxygen ◽  
Oxygen Therapy ◽  
Positive Response ◽  
Low Flow ◽  
Hyperbaric Oxygen Treatment ◽  
Flow Rates ◽  
Oxygen Treatment ◽  
High Flow Oxygen ◽  
Pubmed Search

Purpose Our aim was to review the existing literature to document oxygen’s therapeutic effect on cluster headache. Method A PubMed search resulted in 28 hits, and from these and their references we found in total 11 relevant studies. We included six studies that investigated the efficacy of oxygen treatment. One study is observational and the remaining five are RCTs. Another five studies were on hyperbaric oxygen treatment hereof two case studies. Conclusion Oxygen therapy can be administered at different flow rates. Three studies investigate the effect of low-flow oxygen, 6–7 l/min, and found a positive response in 56%, 75% and 82%, respectively, of the patients. One study investigates high-flow oxygen, 12 l/min, and found efficacy in 78% of attacks. The effect of hyperbaric oxygen therapy has been investigated in a few small studies and there is evidence only for an acute, but not a prophylactic effect. Despite the fact that only a few high-quality RCT studies are available, oxygen treatment is close to an ideal treatment because it is effective and safe. However, sufferers of cluster headache do not always have access to oxygen because of logistic and financial concerns.

scholarly journals The use of oxygen in cluster headache treatment worldwide – a survey of the International Headache Society (IHS)

Cephalalgia ◽  
2016 ◽  
Vol 37 (4) ◽  
pp. 396-398 ◽  
Author(s):  
Stefan Evers ◽  
Alan Rapoport ◽  
Keyword(s):  
Public Health ◽  
Cluster Headache ◽  
International Headache Society ◽  
Headache Attack ◽  
Facial Mask ◽  
Health Authorities ◽  
Cluster Headache Attack ◽  
Headache Treatment ◽  
National Public Health ◽  
Public Health Authorities

Background Oxygen is recommended for the treatment of acute cluster headache attacks. However, it is not available worldwide. Methods The International Headache Society performed a survey among its national member societies on the availability and the restrictions for oxygen in the treatment of cluster headache. Results Oxygen is reimbursed in 50% of all countries responding ( n = 22). There are additional restrictions in the reimbursement of the facial mask and with respect to age. Conclusion Oxygen for the treatment of cluster headache attack is not reimbursed worldwide. Headache societies should pressure national/public health authorities to reimburse oxygen for cluster headache in all countries.

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