Tourette Disorder and Bipolar Symptomatology in Childhood and Adolescence

1989 ◽  
Vol 34 (3) ◽  
pp. 230-233 ◽  
Author(s):  
Jacob Kerbeshian ◽  
Larry Burd
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Manic Episode ◽  
Lithium Carbonate ◽  
Early History ◽  
Childhood And Adolescence ◽  
History Of ◽  
Tourette Disorder

Three boys with an early history of attention deficit disorder with hyperactivity developed Tourette disorder. At 13, 12 and eight years of age, respectively, each met DSM-III criteria for a manic episode or bipolar disorder. Each of the boys had a family history of affective or affective spectrum disorder. Lithium carbonate in a range of 0.8 to 1.2 meq/L markedly improved their bipolar symptomatology with Tourette symptoms improving in two patients. Further study is suggested to determine the significance of these findings.

Unipolar vs. Bipolar Mania: A Review of 247 Patients

1982 ◽  
Vol 141 (5) ◽  
pp. 453-458 ◽  
Author(s):  
Bruce Pfohl ◽  
Ned Vasquez ◽  
Henry Nasrallan
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Chart Review ◽  
Manic Episode ◽  
Unipolar Depression ◽  
Separate Entity ◽  
University Of Iowa ◽  
History Of ◽  
Bipolar Mania ◽  
The University

SummaryPrevious studies attempting to support unipolar mania as an entity distinct from bipolar disorder, have produced conflicting results. The present study reports on a chart review of 247 patients admitted to the University of Iowa with a history of at least one manic episode; 87 of these had apparently never experienced a depression. A subgroup of 92 patients, who met DSM III diagnostic criteria and had a history of at least two episodes of affective disorder, were also examined. There were few clinically meaningful differences between patients with unipolar mania and bipolar disorder on demographic, symptomatic, or familial variables. An earlier report that unipolar manics were more likely to be male and have a family history of unipolar depression was not confirmed. Unipolar mania is not supported as a separate entity from bipolar disorder.

An Isotretinoin-Induced Manic Episode in a Patient with a Family History of Bipolar Disorder

2016 ◽  
Vol 6 (1) ◽  
pp. 43
Author(s):  
Pinar Ozdemir ◽  
Osman Ozdemir ◽  
Mesut Isik ◽  
Serap Bilgili
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Manic Episode ◽  
History Of

Who Responds to Prophylactic Lithium Therapy?

1993 ◽  
Vol 163 (S21) ◽  
pp. 20-26 ◽  
Author(s):  
M. T. Abou-Saleh
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Bipolar Affective Disorder ◽  
Positive Family History ◽  
Specific Treatment ◽  
Predictors Of Outcome ◽  
Powerful Predictor ◽  
Bipolar Illness ◽  
History Of ◽  
Psychotic Features

The search for predictors of outcome has not been particularly rewarding, and the use of lithium remains empirical: a trial of lithium is the most powerful predictor of outcome. However, lithium is a highly specific treatment for bipolar disorder. In non-bipolar affective disorder, factors of interest are correlates of bipolar disorder: mood-congruent psychotic features, retarded-endogenous profile, cyclothymic personality, positive family history of bipolar illness, periodicity, and normality between episodes of illness.

Psychotic symptoms in pediatric bipolar disorder and family history of psychiatric illness

2006 ◽  
Vol 96 (1-2) ◽  
pp. 127-131 ◽  
Author(s):  
Richard Rende ◽  
Boris Birmaher ◽  
David Axelson ◽  
Michael Strober ◽  
Mary Kay Gill ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Psychiatric Illness ◽  
Psychotic Symptoms ◽  
Pediatric Bipolar Disorder ◽  
History Of

Fifteen-Year Follow-up of a Behavioral History of Attention Deficit Disorder

PEDIATRICS ◽  
1985 ◽  
Vol 76 (2) ◽  
pp. 185-190
Author(s):  
David C. Howell ◽  
Hans R. Huessy ◽  
Bruce Hassuk
Keyword(s):  
High School ◽  
Social Adjustment ◽  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Early Adulthood ◽  
Normal Subjects ◽  
Second Grade ◽  
Behavioral History ◽  
Twelfth Grade ◽  
History Of

A 15-year longitudinal study of 369 children originally classified in second grade as exhibiting or not exhibiting behaviors commonly associated with attention deficit disorder was made. Diagnostic data were collected on these children in second, fourth, and fifth grades and subsequent school performance was evaluated after ninth and twelfth grades. Interviews were conducted 3 years after their graduation from high school. The ninth and twelfth grade records reveal that those who had previously been identified as showing behavior related to attention deficit disorder later performed significantly more poorly in school and had poorer social adjustment. Interviews in early adulthood continued to reveal differences in outcome between normal subjects and those earlier classified as having attention deficit disorder. Many of these differences could not be directly attributed to poor academic performance. A subgroup of students who were rated favorably by their elementary school teachers were found to perform better during high school than other members of the normal group in academic areas, but they generally did not differ from normal subjects in nonacademic areas.

Key Research Studies in Clinical Psychopharmacology

2018 ◽  
pp. 483-507
Author(s):  
S. Nassir Ghaemi
Keyword(s):  
Natural History ◽  
Clinical Research ◽  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Clinical Psychopharmacology ◽  
Actual Data ◽  
First Episode ◽  
Bipolar Illness ◽  
History Of ◽  
Research Studies

A number of key clinical research studies in psychopharmacology are presented and critiqued. They include some classic studies dating back decades, to current studies involving the most recent important studies or analyses of clinical research in psychopharmacology—such as diagnostic validators in psychiatry, a maintenance RCT of olanzapine in bipolar illness, brain effects of dopamine blockers, whether antidepressants prevent depression or not, the use of paroxetine in depression, the natural history of treated depression today, adult attention-deficit disorder, and treatment response in first-episode depression. The critiques provided often show that the claimed results of studies are different from the actual data, which need independent interpretation.

Postpartum Psychosis

2020 ◽  
pp. 39-50
Author(s):  
Nikole Benders-Hadi
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Elevated Risk ◽  
Psychotic Symptoms ◽  
Postpartum Psychosis ◽  
Poor Sleep ◽  
Activity Levels ◽  
History Of ◽  
Infant Hospitalization ◽  
Increased Activity

This chapter on postpartum psychosis notes that the risk of postpartum psychosis in the general population is very rare at less than 1%. In a mother with a known history of schizophrenia, this risk increases to 25%. Psychotic symptoms appearing postpartum may also be evidence of a bipolar disorder. The presence of elevated mood, increased activity levels and energy, poor sleep, and a family history of manic episodes all increase the likelihood that a bipolar disorder is present. Women with a personal or family history of a bipolar disorder are at an elevated risk of developing a mania or depression with psychotic symptoms postpartum. Postpartum psychosis due to any cause is a psychiatric emergency and treatment should be initiated early and aggressively to ensure the safety of mother and infant. Hospitalization and/or separation of the baby and mother may be necessary. The use of medication to treat schizophrenia or bipolar disorder during pregnancy may decrease the risk of a postpartum psychosis. With appropriate postpartum medication and support, the majority of women experiencing postpartum psychosis recover well and the risk of recurrent psychotic symptoms can be greatly reduced.

Attention Deficit

2019 ◽  
pp. 54-70
Author(s):  
David L. Brody
Keyword(s):  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Criminal Behavior ◽  
Cognitive Rehabilitation ◽  
Speech Therapy ◽  
Cardiovascular Exercise ◽  
History Of ◽  
Attention Performance ◽  
Mixed Salts ◽  
With Memory

Many concussion patients who complain about problems with memory actually have an attention deficit. General measures: treat insomnia, stop alcohol, treat migraine with cogniphobia, prescribe moderate cardiovascular exercise, and refer for cognitive rehabilitation (occupational and speech therapy). Consider treatment with a stimulant such as methylphenidate (Ritalin) or amphetamine mixed salts (Adderall) if appropriate with careful monitoring for side effects. Contraindications include uncontrolled seizures, dangerous anxiety, active cardiovascular or cerebrovascular disease, active psychosis, drug abuse, irresponsible criminal behavior, dangerously underweight, and uncontrolled headaches. Recommend use 6 days per week 51 weeks per year to reduce tolerance. Additional benefit in some patients from donepezil (Aricept), rivastigmine (Exelon), and regulated caffeine use. Approach options: “aggressive” involving treatment with stimulants primarily based on history, “moderate” involving treatment with stimulants only in patients with attention performance impairments documented with neuropsychological evaluation, and “conservative” not including stimulants unless there is a well-documented preinjury history of attention deficit disorder.

Attention Deficit

2014 ◽  
pp. 35-44
Author(s):  
David L Brody
Keyword(s):  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Criminal Behavior ◽  
Cognitive Rehabilitation ◽  
Speech Therapy ◽  
Cardiovascular Exercise ◽  
History Of ◽  
Attention Performance ◽  
Mixed Salts ◽  
With Memory

Many concussion patients who complain about problems with memory actually have an attention deficit. General measures: treat insomnia, stop alcohol, prescribe moderate cardiovascular exercise, and refer for cognitive rehabilitation (occupational and speech therapy). Consider treatment with a stimulant such as methylphenidate (Ritalin), amphetamine mixed salts (Adderall), and atomoxetine (Strattera), if appropriate, with careful monitoring for side effects. Contraindications include uncontrolled seizures, dangerous anxiety, active cardiovascular or cerebrovascular disease, active psychosis, drug abuse, irresponsible criminal behavior, dangerously underweight, and uncontrolled headaches. Recommend use is 6 days per week 51 weeks per year to reduce tolerance. Some patients find additional benefit from donepezil, rivastigmine, and regulated caffeine use. Approach options: “aggressive,” involving treatment with stimulants primarily based on history; “moderate,” involving treatment with stimulants only in patients with attention performance impairments documented with neuropsychological evaluation; and “conservative,” not including stimulants unless there is a well-documented history of preinjury attention deficit disorder.

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