Neurodevelopmental Outcomes in Very Low-Birth-Weight Infants in Korea

2011 ◽  
Vol 26 (11) ◽  
pp. 1405-1410 ◽  
Author(s):  
Dae-Hyun Jang ◽  
In Young Sung ◽  
Jae Yong Jeon ◽  
Hye Jin Moon ◽  
Ki-Soo Kim ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Birth Weight ◽  
Survival Rate ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Neurodevelopmental Outcomes ◽  
Recent Group ◽  
Neurodevelopmental Impairment ◽  
Over Time

The authors reviewed the medical records of very low-birth-weight infants admitted from 1998 to 2007 and compared neurodevelopmental outcomes with their previously reported data from 1989 to 1997. The recent group included 824 infants, and the previous group included 471 infants. Neurodevelopmental outcomes were classified into cerebral palsy and non–cerebral palsy neurodevelopmental impairment. In the recent group, the survival rate was significantly higher (79.4% vs 66.2%), the rate of cerebral palsy was lower (7.9% vs 10.5%), and the rate of non–cerebral palsy neurodevelopmental impairment was higher (6.0% vs 4.5%) but not significant. The survival rate increased significantly over time, but there was no significant change in neurodevelopmental outcomes over time. Multivariate analysis indicated that abnormal neurosonographic findings, using assisted ventilation, vaginal delivery, and abnormal brainstem auditory evoked potential, were associated with increased risk for cerebral palsy.

scholarly journals Neurodevelopmental outcome of preterm very low birth weight infants admitted to an Italian tertiary center over an 11-year period

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Stefania Longo ◽  
Camilla Caporali ◽  
Camilla Pisoni ◽  
Alessandro Borghesi ◽  
Gianfranco Perotti ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Neurodevelopmental Outcome ◽  
International Studies ◽  
Perinatal Complications ◽  
Neurological Assessment ◽  
Low Birth Weight Infants ◽  
Tertiary Center

AbstractPreterm very low birth weight infants (VLBWi) are known to be at greater risk of adverse neurodevelopmental outcome. Identifying early factors associated with outcome is essential in order to refer patients for early intervention. Few studies have investigated neurodevelopmental outcome in Italian VLBWi. The aim of our longitudinal study is to describe neurodevelopmental outcome at 24 months of corrected age in an eleven-year cohort of 502 Italian preterm VLBWi and to identify associations with outcome. At 24 months, Griffiths’ Mental Developmental Scales were administered. Neurodevelopmental outcome was classified as: normal, minor sequelae (minor neurological signs, General Quotient between 76 and 87), major sequelae (cerebral palsy; General Quotient ≤ 75; severe sensory impairment). 75.3% showed a normal outcome, 13.9% minor sequelae and 10.8% major sequelae (3.8% cerebral palsy). Male gender, bronchopulmonary dysplasia, abnormal neonatal neurological assessment and severe brain ultrasound abnormalities were independently associated with poor outcome on multivariate ordered logistic regression. Rates of major sequelae are in line with international studies, as is the prevalence of developmental delay over cerebral palsy. Analysis of perinatal complications and the combination of close cUS monitoring and neurological assessment are still essential for early identification of infants with adverse outcome.

Lack of Effects of Oral Probiotics on Growth and Neurodevelopmental Outcomes in Preterm Very Low Birth Weight Infants

2010 ◽  
Vol 156 (3) ◽  
pp. 393-396 ◽  
Author(s):  
I-Ching Chou ◽  
Haung-Tsung Kuo ◽  
Jeng-Sheng Chang ◽  
Shu-Fen Wu ◽  
Hsiao-Yu Chiu ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Neurodevelopmental Outcomes

scholarly journals Survival rate dependent variations in retinopathy of prematurity treatment rates in very low birth weight infants

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jae Hyun Park ◽  
Jong Hee Hwang ◽  
Yun Sil Chang ◽  
Myung Hee Lee ◽  
Won Soon Park
Keyword(s):  
Birth Weight ◽  
Survival Rate ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Very Low Birth Weight ◽  
Target Range ◽  
Treatment Rate ◽  
Low Birth Weight Infants ◽  
Rate Dependent ◽  
Group I

Abstract As increased oxidative stress causes increased mortality and morbidities like bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) in very low birth weight infants (VLBWIs), the conundrum of improved survival but increased ROP observed with the high oxygen saturation target range of 91–95% is difficult to explain. To determine the survival rate-dependent variation in ROP treatment rate, 6292 surviving eligible VLBWIs registered in the Korean Neonatal Network were arbitrarily grouped according to the survival rate of infants at 23–24 weeks’ gestation as group I (> 70%, n = 1626), group II (40–70%, n = 2984) and group III (< 40%, n = 1682). Despite significantly higher survival and lower BPD rates in group I than in groups II and III, the ROP treatment rate was higher in group I than in groups II and III. However, the adjusted odds ratios for ROP treatment were not significantly different between the study groups, and the ROP treatment rate in the infants at 23–24 weeks’ gestation was 21-fold higher than the infants at ≥ 27 weeks’ gestation. The controversial association between improved survival and reduced BPD reflecting quality improvement of neonatal intensive care but increased ROP treatment rate might be primarily attributed to the improved survival of the most immature infants.

Increased Survival Rate in Very Low Birth Weight Infants (1500 Grams or Less)

1991 ◽  
Vol 46 (4) ◽  
pp. 215-216
Author(s):  
JENS B. GROGAARD ◽  
DANIEL P. LINDSTROM ◽  
ROBERT A. PARKER ◽  
BARBARA CULLEY ◽  
MILDRED T. STAHLMAN
Keyword(s):  
Birth Weight ◽  
Survival Rate ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants
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