Amino-functionalized mesoporous silica nanoparticles as efficient carriers for anticancer drug delivery

2017 ◽  
Vol 32 (4) ◽  
pp. 524-532 ◽  
Author(s):  
Yongju He ◽  
Liangyu Luo ◽  
Shuquan Liang ◽  
Mengqiu Long ◽  
Hui Xu
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Anticancer Drug ◽  
Mesoporous Silica Nanoparticles ◽  
Anticancer Drug Delivery ◽  
Functionalized Mesoporous Silica

In vivo evaluation of an anticancer drug delivery system based on heparinized mesoporous silica nanoparticles

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 40103-40110 ◽  
Author(s):  
Qiang Wu ◽  
Ruifang Li ◽  
Chao Zhao ◽  
Jiejie Ren ◽  
Keyuan Du ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
In Vivo Evaluation ◽  
Anticancer Drug Delivery

MSNs-HP loaded with only a low amount of a drug (DOX0.3) achieve a similar antitumor efficacy to that of large doses of the drug (DOX2.0, 7-fold higher in dosage than DOX0.3).

Redox-sensitive mesoporous silica nanoparticles functionalized with PEG through a disulfide bond linker for potential anticancer drug delivery

RSC Advances ◽  
2015 ◽  
Vol 5 (73) ◽  
pp. 59576-59582 ◽  
Author(s):  
Huameng Gong ◽  
Zhifei Xie ◽  
Mingxing Liu ◽  
Hongda Zhu ◽  
Honghao Sun
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Anticancer Drug ◽  
Disulfide Bond ◽  
Mesoporous Silica Nanoparticles ◽  
Thiol Group ◽  
Anticancer Drug Delivery ◽  
Methoxy Polyethylene Glycol

In this paper, redox-sensitive mesoporous silica nanoparticles (MSNs–SS–PEG) were successfully synthesized using silica nanoparticles modified with a thiol group (MSNs–SH) and thiol-functionalized methoxy polyethylene glycol (MeOPEG–SH).

Multifunctional Gd-based mesoporous silica nanotheranostic for anticancer drug delivery

2019 ◽  
Vol 7 (19) ◽  
pp. 3143-3152 ◽  
Author(s):  
Fabio Carniato ◽  
Diego Alberti ◽  
Angelica Lapadula ◽  
Jonathan Martinelli ◽  
Ciro Isidoro ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Anticancer Drug ◽  
Mesoporous Silica Nanoparticles ◽  
Anticancer Drug Delivery ◽  
High Relaxivity ◽  
Rhodamine Dyes

A theranostic MRI nanoprobe based on mesoporous silica nanoparticles with attached stable Gd-complexes with high relaxivity, rhodamine dyes, PEG and cyclooctyne moieties was synthesized and loaded with mitoxantrone for bio-orthogonal targeted anticancer drug delivery.

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