Methadone Maintenance Treatment Versus Methadone Maintenance Treatment Plus Auricular Acupuncture

2013 ◽  
Vol 26 (6) ◽  
pp. 541-550 ◽  
Author(s):  
Pei Lin Lua ◽  
Nor Samira Talib ◽  
Zabidah Ismail

This study intended to (1) describe the baseline patient satisfaction level and preferred coping strategies and (2) assess patient satisfaction and coping mechanisms pre- and postintervention. Patients on methadone maintenance treatment (MMT) in Terengganu, Malaysia, were randomized into either MMT or MMT plus auricular acupuncture (MMT + AA) groups. All received the standard MMT, while participants on MMT + AA underwent concurrent AA session thrice weekly for 2 months (each session = 30 minutes). Data analysis was carried out using SPSS 16.0, employing descriptive and nonparametric statistics. Participations were received from 97 eligible male patients (median age = 36.0 years; Malay = 97.9%). After screening for dropouts, only 69 patients were considered for subsequent analysis (MMT = 40; MMT + AA = 29). At preintervention, both groups did not differ significantly in the parameters investigated. During postintervention, no significant difference was detected for satisfaction level but coping-wise, substance use was significantly and frequently adopted by MMT + AA patients compared to MMT respondents ( P < .05). On separate analysis, those who received MMT alone adopted active coping, venting, and self-blame significantly more frequently postintervention ( P < .05). Nevertheless, no significant difference for coping styles of MMT + AA patients was exhibited over time ( P >.05). The addition of AA therapy into the standard MMT treatment did not seem to influence patient satisfaction and their coping ways.

2020 ◽  
Vol 71 (4) ◽  
pp. 353-358
Author(s):  
Davorka Sutlović ◽  
Željko Ključević ◽  
Sendi Kuret

AbstractThe aim of this study was to determine the influence of ABCB1, CYP2B6, and CYP3A4 genetic polymorphisms on methadone metabolism in patients with hepatitis C virus (HCV) undergoing methadone maintenance treatment (MMT). The study included 35 participants undergoing MMT, who were divided in three groups: HCV-positive (N=12), HCV-negative (N=16), and HCV clinical remission (CR) (N=7). The concentrations of methadone and its main metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) were determined with gas chromatography-mass spectrometry. The patients were genotyped for ABCB1 rs1045642, CYP2B6 rs3745274, CYP3A4 rs2242480, and CYP3A4 rs2740574 polymorphisms. Differences between single nucleotide polymorphism (SNP) genotypes and methadone-to-EDDP ratio were analysed with one-way ANOVA, which showed no significant difference between the genes (p=0.3772 for ABCB1 rs1045642, p=0.6909 for CYP2B6 rs3745274, and p=0.6533 for CYP3A4 rs2242480). None of the four analysed SNP genotypes correlated with methadone-to-EDDP concentration ratio. A major influence on it in hepatitis C-positive patients turned out to be the stage of liver damage.


2019 ◽  
Vol 11 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Amir Jalali ◽  
Mahvash K. Behrouzi ◽  
Nader Salari ◽  
Mohammad-Rafi Bazrafshan ◽  
Mahmoud Rahmati

Background: Drug dependence or substance use disorder not only affects a person’s life but also brings a lot of challenges for families and communities and imposes heavy burdens on them. There are various therapies in the domain of addiction whose main purposes are to reduce or to cut down substance abuse. Objective: This study aimed to determine the effectiveness of group spiritual intervention on selfesteem and happiness among male clients undergoing methadone maintenance treatment. Methods: This study was an intervention study in which 60 clients affected with substance abuse and undergoing methadone maintenance treatment were recruited. The study samples were selected through convenience sampling method and then divided randomly into two groups of 30 individuals: intervention and control. The intervention group attended group spiritual interventions for 10 sessions. Self-esteem and happiness among the study participants were also measured through Coopersmith Self-Esteem Inventory and Oxford Happiness Questionnaire before and after the intervention. Results: The results showed a significant difference between both intervention and control groups in terms of self-esteem and happiness (P < 0.05); so that the participants in the intervention group demonstrated a significant improvement in their self-esteem and happiness. Conclusion: It was concluded that group spiritual intervention as a useful method could be effective in enhancing self-esteem and happiness among addicted individuals undergoing methadone maintenance treatment. The given treatment could be also used as a complementary therapy beside methadone maintenance treatment to reduce the likelihood of people returning to substance abuse.


2016 ◽  
Vol 9 (2) ◽  
pp. 15 ◽  
Author(s):  
Reza Mollajavadi ◽  
Narges Beyraghi ◽  
Isa Fathi ◽  
Robab Teymouri ◽  
Arya Hamedanchi

<p><strong>BACKGROUND:</strong> Despite the considerable efforts made in Iran to treat people with addiction, relapse is still common. This study was designed to determine retention and relapse rates and related factors at Yasin Methadone Maintenance Treatment Center.</p><p><strong>PATIENTS &amp; METHODS:</strong> In this study, retention rate, relapse rate, and related factors were examined in 74 cases using a descriptive-analytical method. Information about 20 variables were gathered from patient medical records using an information form and a checklist and data was analyzed by the chi-square, Fisher’s exact, and Mann-Whitney tests using SPSS software.</p><p><strong>FINDINGS:</strong> The retention and relapse rates were 24.3% and 75.7%, respectively. Only three factors showed a significant difference (p&lt;0.50) between the retention and relapse groups: (1) financial status, (2) motivation for treatment, and (3) cooperation during counseling (p=0.04, p=0.001, p=0.026, respectively). No significant differences were observed between groups for the other factors.</p><p><strong>CONCLUSION:</strong> Because it is clear that financial status, motivation, and counseling can affect retention rate, it is recommended to study the effect of these factors on retention using methods such as a randomized clinical trial.</p>


2007 ◽  
Vol 89 (2-3) ◽  
pp. 190-194 ◽  
Author(s):  
José Pérez de los Cobos ◽  
Núria Siñol ◽  
Joan Trujols ◽  
Elisabeth del Río ◽  
Enrique Bañuls ◽  
...  

2012 ◽  
Vol 123 (1-3) ◽  
pp. 41-47 ◽  
Author(s):  
Joan Trujols ◽  
Inmaculada Garijo ◽  
Núria Siñol ◽  
Juan del Pozo ◽  
Maria J. Portella ◽  
...  

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