Pharmacy Involvement With Positron-Emitting Radiopharmaceuticals

1989 ◽  
Vol 2 (3) ◽  
pp. 185-190
Author(s):  
Ronald G. Manning ◽  
Robert G. Wolfangel

Positron emission tomography (PET) is an imaging process that relies on positron-emitting nuclides with very short physical half-lives (ranging from seconds to minutes). Exceptional resolution in PET imaging enables studies of the CNS (eg, highlighting deviant cell metabolism), and cardiovascular system (eg, identifying areas of reduced blood flow before coronary artery bypass surgery), among others. Increasing in popularity, PET radiopharmaceuticals pose a unique challenge to the nuclear pharmacist relative to product synthesis and quality control testing. Establishment of process validation programs with emphasis on quality, purity, and safety is all important. Various elements of process validation and quality control testing are discussed as they pertain to PET radiopharmaceuticals and the professional role of the nuclear pharmacist.

Author(s):  
Xiumei Sun ◽  
Jennifer Ellis ◽  
Louis Kanda ◽  
Robert Lowery ◽  
Steven W Boyce ◽  
...  

Background: Previous studies have shown that female gender is an independent predictor of increased operative mortality after coronary artery bypass surgery. It remains inconsistent whether female gender is associated with increased mortality after aortic valve replacement (AVR). The purpose of this study is to investigate the role of female gender inoperative mortality after AVR. Methods: The study population included isolated AVR performed between January 2003 and December 2012 at a single Instituation. Results: During this period, 1,262 patients underwent isolated AVR. The major preoperative characteristics and operative outcomes are detailed in the following table. R>Conclusions: In this study, female patients had increased operative mortality after isolated AVR.


Hypertension ◽  
1980 ◽  
Vol 2 (3) ◽  
pp. 291-298 ◽  
Author(s):  
P K Whelton ◽  
J T Flaherty ◽  
N P MacAllister ◽  
L Watkins ◽  
A Potter ◽  
...  

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