E-commerce or electronic commerce refers to the exchange of goods, services, funds or information between business and consumers using the electronic network where all the activities like purchasing, selling, ordering, and paying are performed over the internet. During Covid-19 Pandemic while supply chains and logistics sectors have undergone major disruptions several persons logged on to various e-commerce websites to make safe virtual purchases of various items including basic essentials such as groceries, medicines, food items along with luxury and lifestyle purchases. In this way it is observed that in-spite of various challenges such as manufacturing slowdown, transportation problem, unavailabilty of labour and disruption of national and international supply chains there has been a massive growth in the e-commerce sector during COVID-19. In this paper we will study the challenges and aspects of e-commerce during and post Covid-19 along with a Special Reference to the development of North East India with the help of e-commerce sector. In order to conduct the study both primary and secondary data have been collected by two stage sampling technique in the cities of Kolkata (West Bengal ) and Guwahati (Assam).