Measurement of IgG Concentration in Ovine Fetal Fluids: A Useful Diagnostic Test

The Veterinary Diagnostic Laboratory at Oregon State University received 172 aborted ovine fetuses during the 1985–1987 lambing seasons; from 120 of these, body fluids were evaluated for IgG levels. Fifty-two (43%) of the fetal fluids had immunoglobulin G (IgG) levels greater than 15 mg/dl. Forty-five (87%) of the fluids with elevated IgG levels were confirmed or presumed toxoplasma or Chlamydia abortions. A mean fetal fluid IgG concentration of 111.5 ± 78 mg/dl was found for the 26 toxoplasma abortions; for the 19 Chlamydia abortions, a mean IgG concentration of 109 ± 91 mg/dl was found. Antibody titers equal to or greater than 1:40 against Toxoplasma gondii were detected in 23 fetal fluids. Fetal fluid IgG concentration less than 15 mg/dl was found to be associated with bacterial organisms (i.e., Campylobacter sp.) as the confirmed or presumed cause of abortion. These results suggest that measurement of fetal fluid IgG concentration is a useful, supportive diagnostic test in determining the cause of ovine abortion, and should be included as a routine laboratory procedure for ovine abortion diagnosis.

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An Indirect Microimmunofluorescence Test for Detection of Chlamydial Antibodies in Ovine Fetal Fluids

Journal of Veterinary Diagnostic Investigation ◽

10.1177/104063879400600306 ◽

1994 ◽

Vol 6 (3) ◽

pp. 315-320 ◽

Cited By ~ 4

Author(s):

T. P. Sanderson ◽

A. A. Andersen ◽

L. D. Miller ◽

J. J. Andrew ◽

B. H. Janke ◽

...

Keyword(s):

Chlamydial Infection ◽

Complement Fixation Test ◽

Complement Fixation ◽

Rapid Test ◽

Chlamydia Psittaci ◽

Diagnostic Laboratory ◽

Specific Antibodies ◽

Ovine Fetal ◽

Microimmunofluorescence Test ◽

Fetal Fluids

The objective of this study was to evaluate an indirect microimmunofluorescence test (IMIF) for detection of Chlamydial antibodies in serum and/or thoracic fluids of aborted ovine fetuses. One hundred eighty-two ovine fetuses, including 64 fetuses from 40 ewes that were experimentally infected with an ovine abortion strain of Chlamydia psittaci at gestation days 90–100, 10 fetuses from 6 normal ewes, and 108 fetuses selected from those received at the Iowa Veterinary Diagnostic Laboratory, were evaluated in this study. Fetuses from experimentally infected ewes were examined 4–60 days after inoculation. The IMIF findings were compared with the results of complement fixation serology for Chlamydiae and concentrations of immunoglobulin (IgG). Chlamydiae-specific antibodies were detected by IMIF in 28 of 38 fetuses infected with C. psittaci. Elevated levels of IgG and IMIF titers ≥ 1:8 were consistent findings in ovine fetuses infected with Chlamydiae for more than 24 days. IgG levels and titers of Chlamydial antibodies increased with maturity of the fetus and duration of Chlamydial infection. Chlamydial antibodies were not detected with the complement fixation test. Fluids from ovine fetuses aborted as a result of other causes also were examined, and IMIF results were negative. The results of this study indicate that the IMIF is a useful and relatively rapid test for identification of Chlamydial antibodies in ovine fetuses.

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Characterization of the Microanatomy and Histopathology of Placentas From Aborted, Stillborn, and Normally Delivered Alpacas (Vicugna pacos) and Llamas (Lama glama)

Veterinary Pathology ◽

10.1177/0300985811406889 ◽

2011 ◽

Vol 49 (2) ◽

pp. 313-321 ◽

Cited By ~ 4

Author(s):

D. L. Schaefer ◽

R. J. Bildfell ◽

P. Long ◽

C. V. Löhr

Keyword(s):

Placental Insufficiency ◽

State University ◽

Diagnostic Laboratory ◽

Crown Rump Length ◽

Routine Testing ◽

Vicugna Pacos ◽

Microscopic Features ◽

Lama Glama ◽

Oregon State University

From 2002 to 2007, 101 camelid abortions and stillbirths were submitted to the Veterinary Diagnostic Laboratory at Oregon State University (84 alpacas [ Vicugna pacos], 13 llamas [ Lama glama], 4 unknown). For most cases ( n = 67), a cause was not determined by routine testing. Eighty-five submissions included placenta for microscopic examination, of which 55 were from abortions to unknown causes (idiopathic). Microscopic features of placentas from abortion/stillbirth were compared with those from 19 camelids delivered normally (6 alpacas, 12 llamas, 1 unknown) and with those from 4 alpaca fetuses of known gestational age collected during the dam’s necropsy. The most common microscopic findings in abortion/stillbirth placentas were mineralization ( n = 57) and mucinous edema ( n = 27) of the chorioallantoic stroma. One or more of these features were also observed in 22 of 23 placentas from normal pregnancies/deliveries and therefore interpreted as incidental findings. The comparison of alpaca placentas after matching for gestational parameters (crown–rump length, weight, days of gestation; n = 41) revealed hypoplasia of placental villi in 5 of 22 idiopathic abortions and in 1 abortion due to umbilical torsion; hypoplasia was further suspected in an additional 6 abortions of unknown cause and 2 abortions of known cause. The identified villous hypoplasia is assumed to have resulted in placental insufficiency. When placental insufficiency is included as cause, idiopathic abortions are reduced from 66.2 to 47.9% of alpaca cases with histopathologic examination of placenta and from 66.3 to 52.5% of alpaca and llama abortions overall. This study also permitted the generation of a linear regression curve correlating alpaca fetal crown–rump length with fetal age.

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Ultrastructural Studies of Bovine Respiratory Disease Complex

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100115766 ◽

1975 ◽

Vol 33 ◽

pp. 428-429

Author(s):

James C.S. Kim

Keyword(s):

Michigan State University ◽

State University ◽

Diagnostic Laboratory ◽

Ultrastructural Studies ◽

Bovine Respiratory Diseases ◽

Etiologic Agents ◽

Diagnostic Difficulties ◽

The Subject ◽

Capillary Walls ◽

Alveolar Capillary

Bovine respiratory diseases cause serious economic loses and present diagnostic difficulties due to the variety of etiologic agents, predisposing conditions, parasites, viruses, bacteria and mycoplasma, and may be multiple or complicated. Several agents which have been isolated from the abnormal lungs are still the subject of controversy and uncertainty. These include adenoviruses, rhinoviruses, syncytial viruses, herpesviruses, picornaviruses, mycoplasma, chlamydiae and Haemophilus somnus.Previously, we have studied four typical cases of bovine pneumonia obtained from the Michigan State University Veterinary Diagnostic Laboratory to elucidate this complex syndrome by electron microscopy. More recently, additional cases examined reveal electron opaque immune deposits which were demonstrable on the alveolar capillary walls, laminae of alveolar capillaries, subenthothelium and interstitium in four out of 10 cases. In other tissue collected, unlike other previous studies, bacterial organisms have been found in association with acute suppurative bronchopneumonia.

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McKELVEY, S. D. Botanical exploration of the trans-Mississippi west 1790–1850. (Northwest Reprints; original edition published by The Arnold Arboretum of Harvard University, Jamaica Plain: 1955.) Oregon State University Press, Corvallis, Oregon: 1991. Pp xviii, [10], 'xiii-xl', 1144; maps. Price: none stated. ISBN: 0-87071-513-5.

Archives of Natural History ◽

10.3366/anh.1993.20.3.438a ◽

1993 ◽

Vol 20 (3) ◽

pp. 438-439

Author(s):

E. W. GROVES

Keyword(s):

Harvard University ◽

State University ◽

Arnold Arboretum ◽

Botanical Exploration ◽

Oregon State University ◽

Original Edition

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Why Age Matters to Higher Education: Age-Friendly Tools and Techniques for Culture Change

Innovation in Aging ◽

10.1093/geroni/igaa057.1804 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 551-551

Author(s):

David Burdick ◽

Karen Rose ◽

Dana Bradley

Keyword(s):

University Presidents ◽

Steering Committee ◽

State University ◽

Community Members ◽

University Leadership ◽

Drexel University ◽

College Of Nursing ◽

Tools And Techniques ◽

The University ◽

Oregon State University

Abstract Momentum is growing for the Age-Friendly University Network as proponents, primarily gerontology educators, have successfully encouraged university presidents to sign nonbinding pledged to become more age-friendly in programs and policies, endorsing 10 Age-Friendly University Principles. While this trend is inspiring, more is needed to fully achieve benefits for universities, students, communities, and older adults. Four presentations discuss innovative ways of deepening university commitment, weaving the principles into the fabric of the university. The first paper describes thematic content analysis from five focus groups with admissions and career services staff at Washington University in St. Louis and the recommendations that emerged for the provision of programs and services for post-traditional students. The second paper describes efforts to utilize community-impact internships and community partnerships to build support for Age-Friendly University initiatives at Central Connecticut State University, particularly in the context of the university’s recent Carnegie Foundation Engaged Campus designation. The third paper describes how Drexel University became Philadelphia’s first Age-Friendly University and current efforts in the Drexel College of Nursing and Heatlh Care Profession’s AgeWell Collaboratory to convene university-wide leadership for an AFU Steering Committee working on four mission-driven efforts to ensure AFU sustainability. The fourth paper describes steps taken by AFU proponents at Western Oregon State University to gain endorsement from university leadership and community, including mapping the 10 AFU Principles to the university’s strategic plan, faculty senate endorsement, and survey/interview results of older community members’ use of the university, which collectively have enhanced deeper and broader campus buy-in of AFU.

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