Identification and Characterization of Adverse Drug Events in Primary Care

2016 ◽  
Vol 32 (5) ◽  
pp. 518-525 ◽  
Author(s):  
Katy E. Trinkley ◽  
Harrison G. Weed ◽  
Stuart J. Beatty ◽  
Kyle Porter ◽  
Milap C. Nahata

The purpose of this study was to identify and characterize adverse drug events (ADEs) in a primary care setting using an electronic health record (EHR). This prospective, observational study enrolled patients with any medication change who were seen at an outpatient internal medicine clinic. Patients were evaluated for ADEs by EHR review and telephone interview. ADEs were independently assessed for causality, severity, preventability, and ameliorability by a physician and a pharmacist using a grading instrument. There were 1368 unique medication changes for 701 individuals who completed the study (1.95 changes per person). Of the 226 suspected ADEs, 68 (58%) were deemed to be “definite” or “probable” following causality assessment; 21% were preventable and 40% ameliorable. Only 2 ADEs were serious or life-threatening. Compared with prior reports, ADEs in primary care have decreased in frequency and severity, yet the occurrence of preventable and ameliorable ADEs has increased.

2016 ◽  
Vol 9 (12) ◽  
pp. 753-761
Author(s):  
Rabia Aftab

Dealing with a medical emergency in an environment with limited life-saving resources is a frightening situation. Oncology emergencies can be especially challenging and life-threatening. Although these rarely present in primary care, they require specific urgent treatment, and therefore their recognition is important. This article intends to give an insight into diagnosis and management of oncology emergencies in a primary care setting.


2009 ◽  
Vol 29 (7) ◽  
pp. 441-450 ◽  
Author(s):  
Concepción Pérez ◽  
María Teresa Saldaña ◽  
Ana Navarro ◽  
Inma Vilardaga ◽  
Javier Rejas

2020 ◽  
Vol 11 ◽  
pp. 215013272091729
Author(s):  
Alexis Dellogono ◽  
Aimee Dawson ◽  
Marisa Piers-Gamble ◽  
Jerril Varghese ◽  
Lori Lewicki

Objectives: The objective of this study was to identify and evaluate medication-related problems (MRPs) found during hospital discharge transitions of care visits in a primary care setting. Design, Settings, and Participants: This retrospective cohort took place within a federally qualified health center (FQHC) where pharmacists are part of the interprofessional transitions of care team to help patients transition back to primary care after being discharged from the hospital. Pharmacists utilized standardized forms to document MRPs, potential and adverse drug events, and interventions made during the visit. This study quantifies the role that pharmacists can have by conducting medication reconciliation during postdischarge primary care visits. Patients included in this study were 18 years and older with at least 5 medications. Outcome Measures: The outcomes of this study include the number and type(s) of MRPs, number and severity of potential adverse drug events (pADEs) and adverse drug events (ADEs) that were identified, as well as the number and type of recommendations or interventions made by the pharmacist. The MRP types and pADE/ADE severity were classified and stratified using predetermined definitions. Results: During the 4-month study period from October 1, 2018 to February 4, 2019, 134 visits were completed. Outcomes included a total of 454 MRPs, with an average of 3 identified per visit. The most common MRPs were medication list in electronic health record inaccurate (79.1% of visits), poor adherence (32.1% of visits), and refills needed (30.6% of visits). A total of 72 pADEs and 27 ADEs were identified, with 524 recommendations made. Conclusion: Pharmacists serve a unique role during transitions of care by identifying MRPs. Pharmacists are an integral part of a patient’s health care team by making recommendations or interventions related to these MRPs. FQHCs and other primary care settings should consider integrating pharmacists into a collaborative transitions of care team.


2007 ◽  
Vol 177 (4S) ◽  
pp. 494-495 ◽  
Author(s):  
Michael Naslund ◽  
Alicia Gilsenan ◽  
Kirk Midkiff ◽  
Eric Wolford ◽  
Aileen Bown ◽  
...  

2008 ◽  
Author(s):  
Ruth Elaine Graves ◽  
Tanya N. Alim ◽  
Notalelomwan Aigbogun ◽  
Thomas A. Mellman ◽  
William B. Lawson

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