scholarly journals Predictors of Medication Adherence in the Elderly: The Role of Mental Health

2017 ◽  
Vol 75 (6) ◽  
pp. 746-761 ◽  
Author(s):  
Jo E. Rodgers ◽  
Emily M. Thudium ◽  
Hadi Beyhaghi ◽  
Carla A. Sueta ◽  
Khalid A. Alburikan ◽  
...  

The aging population routinely has comorbid conditions requiring complicated medication regimens, yet nonadherence can preclude optimal outcomes. This study explored the association of adherence in the elderly with demographic, socioeconomic, and disease burden measures. Data were from the fifth visit (2011-2013) for 6,538 participants in the Atherosclerosis Risk in Communities Study, conducted in four communities. The Morisky–Green–Levine Scale measured self-reported adherence. Forty percent of respondents indicated some nonadherence, primarily due to poor memory. Logit regression showed, surprisingly, that persons with low reading ability were more likely to report being adherent. Better self-reported physical or mental health both predicted better adherence, but the magnitude of the association was greater for mental than for physical health. Compared with persons with normal or severely impaired cognition, mild cognitive impairment was associated with lower adherence. Attention to mental health measures in clinical settings could provide opportunities for improving medication adherence.

1990 ◽  
Vol 156 (4) ◽  
pp. 596-597
Author(s):  
J. J. Hart

What should one offer to undergraduates as recommended reading for the 1990s? Since the question was last addressed in this journal (Mindham, 1982) much in psychiatry has altered. The student needs to be aware of the reorganisation of mental health services, with the closure of many old hospitals and the push into the community. Other changes include a growth in the elderly population, an ever-increasing number of psychotropic drugs, more emphasis on the multidisciplinary approach and the role of substance abuse in mental disorder, and the strengthened relationship between psychiatry and both general practice and other hospital medical services. There has been new mental health legislation since 1982, and the future doctor will also need to adjust to the advent of NHS reforms, with all its ramifications.


LGBT Health ◽  
2014 ◽  
Vol 1 (4) ◽  
pp. 319-322 ◽  
Author(s):  
Jaclyn M. White ◽  
Janna R. Gordon ◽  
Matthew J. Mimiaga

2021 ◽  
Vol 67 ◽  
pp. 101718
Author(s):  
Xiumei Ma ◽  
Xiaofei Zhang ◽  
Xitong Guo ◽  
Kee-hung Lai ◽  
Doug Vogel
Keyword(s):  

2021 ◽  
pp. 0271678X2110008
Author(s):  
Cellas A Hayes ◽  
M Noa Valcarcel-Ares ◽  
Nicole M Ashpole

Ischemic strokes are highly prevalent in the elderly population and are a leading cause of mortality and morbidity worldwide. The risk of ischemic stroke increases in advanced age, corresponding with a noted decrease in circulating insulin growth factor-1 (IGF-1). IGF-1 is a known neuroprotectant involved in embryonic development, neurogenesis, neurotransmission, cognition, and lifespan. Clinically, several studies have shown that reduced levels of IGF-1 correlate with increased mortality rate, poorer functional outcomes, and increased morbidities following an ischemic stroke. In animal models of ischemia, administering exogenous IGF-1 using various routes of administration (intranasal, intravenous, subcutaneous, or topical) at various time points prior to and following insult attenuates neurological damage and accompanying behavioral changes caused by ischemia. However, there are some contrasting findings in select clinical and preclinical studies. This review discusses the role of IGF-1 as a determinant factor of ischemic stroke outcomes, both within the clinical settings and preclinical animal models. Furthermore, the review provides insight on the role of IGF-1 in mechanisms and cellular processes that contribute to stroke damage.


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