scholarly journals Health-related quality of life among cervical cancer patients at Kenyatta National Hospital

2022 ◽  
pp. 107815522110738
Author(s):  
Mehreen Shajahan Ahamed ◽  
Amsalu Degu
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
National Hospital ◽  
Good Hrqol ◽  
Stage Disease ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq

Background Previous study showed that health-related quality of life (HRQoL) was adversely affected during treatment of cervical cancer, with a worsening global score. Therefore, this study aimed to determine the HRQoL of cervical cancer patients at Kenyatta National Hospital. Methods A cross-sectional study design was employed among cervical cancer patients. All eligible consecutive samples of 103 cervical cancer patients were included in the study. Following consent, patients were interviewed using The European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire 30 (EORTC QLQ-30) and Cervical Cancer Module CX24 (EORTC QLQ-CX24). The data were entered and analyzed using the SPSS version 20.0 software. Univariate and multivariate binary logistic regression analysis was employed to investigate the predictors of HRQoL. A p-value of ≤ 0.05 was considered statistically significant. Results The majority (69%) of the patients had a poor overall quality of life while 31% of study participants had a good quality of life. Patients with early-stage disease were 7.3 times (AOR = 7.3, 95% CI = 2.4–21.7, p = 0.000) more likely to have a good HRQoL than patients with advanced-stage disease. Patients with no comorbidities were 3.1 times (COR = 3.1, 95% CI = 1.1–9.1, p = 0.037) more likely to have a good HRQoL than patients with comorbidities. Conclusion The overall HRQoL among cervical cancer patients was poor in the setting. Advanced stage of disease and presence of comorbidities were the significant predictors of poor quality of life.

scholarly journals Health-related Quality of Life Among Cervical Cancer Patients at Kenyatta National Hospital

2021 ◽  
Author(s):  
Mehreen Shajahan Ahamed ◽  
Amsalu Degu
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
Poor Quality ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
Study Participants

Abstract Background: A previous systematic review showed that health-related quality of life (HRQoL) was adversely affected during treatment of cervical cancer, with a worsening global score. However, there was a lack of data in the study setting. Therefore, this study aimed to determine the HRQoL of cervical cancer patients at Kenyatta National Hospital.Methods: A cross-sectional design of the study was employed among cervical cancer patients. All eligible cervical cancer patients during the study period were included in the study. Hence, a consecutive sample of 103 cervical cancer patients was involved in the study. Following consent, study participants were interviewed using The European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire 30 (EORTC QLQ-30) and Cervical Cancer Module CX24 (EORTC QLQ-CX24). The clinical characteristics and treatment regimens were collected by reviewing the medical records. Interpretation and linear transformation of the raw score of health-related quality of life were conducted as per EORTC QLQ 30 and EORTC QLQ-CX24 Scoring Manual. The data were entered and analyzed using the Statistical Package for Social Sciences version 20.0 software. Frequency tables mean, percentage, and figures were used to represent the data. Univariate and multivariate binary logistic regression analysis was employed to investigate the associated factors of health-related quality of life. A p-value of ≤ 0.05 was considered statistically significant. Results: The mean age of the participant population was found to be 55.8 ± 5.6 years. Most of the study participants had stage III cervical cancer (56.3%) and without comorbidities (65%). The mean score of the global health status was 41.99. The physical functioning, cognitive functioning, and financial difficulties mean scores were 71.6, 73.3, and 93.5, respectively. Under the symptom scale, nausea and vomiting, pain, and appetite loss had mean scores of 70.1, 67.2, and 66.0, respectively. The overall quality of life data showed 69% of study participants had poor quality of life while 31% of study participants had good quality of life. Patients with early-stage disease (stage I and II) were 7.3 times (AOR = 7.3, 95% CI = 2.4 – 21.7, p = 0.000) more likely to have a good quality of life than patients with advanced-stage disease. Patients with no comorbidities were 3.1 times (COR = 3.1, 95% CI = 1.1 – 9.1, p = 0.037) more likely to have a good quality of life than patients with comorbidities.Conclusions: The overall health-related quality of life among cervical cancer patients was poor in the study setting. Advanced stage of disease and presence of comorbidities were the significant predictors of poor quality of life.

scholarly journals Reliability and validity of Amharic version of EORTC QLQ-C30 and QLQ-BR23 modules for assessing health-related quality of life among breast cancer patients in Ethiopia

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Diriba Alemayehu Gadisa ◽  
Esayas Tadesse Gebremariam ◽  
Getnet Yimer Ali
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Breast Cancer Patients ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Health Related ◽  
Eortc Qlq

Abstract Background Breast cancer is the most common cancer among women and it affects quality of life of those women. So far, the two most frequently used tools for assessing health related quality of life in breast cancer patients, EORTC QLQ-C30 and EORTC QLQ-BR23 modules, were not validated in Ethiopia. Hence, the present study aimed to assess the psychometric properties of the tools among Ethiopian breast cancer patients. Methods Institutional based longitudinal study was conducted from January 1 to May 1, 2017 GC at only nationwide oncology center, Tikur Anbessa Specialized Hospital (TASH), Addis Ababa, Ethiopia. A total of 146 patients who visited the facility during that period, with no missing quality of life data, were selected for analysis. The psychometric properties of the EORTC QLQ-C30 and EORTC QLQ-BR23 were evaluated in terms of reliability, convergent, divergent, construct and clinical validity using SPSS version 22. Results Satisfactory internal consistency reliability (Cronbach’s α coefficients > 0.7) was confirmed, except for cognitive function (α = 0.516) of EORTC QLQ-C30 and body image (α = 0.510) of EORTC QLQ-BR23. Multiple-trait scaling analysis demonstrated a good convergent and divergent validity. No scaling errors were observed. Most items in EORTC QLQ-BR23 possessed a weak or no correlation with its own dimension in EORTC QLQ-C30 (r < 0.4) except with some of symptom scales. A statistically significant chemotherapy induced quality of life scores changes (P ≤ 0.05) were observed in all dimensions of both instruments between baseline and the end of first cycle chemotherapy, except for body image (P = 0.985) and sexual enjoyment (P = 0.817) of EORTC QLQ-BR23, indicating clinical validity. Conclusion Amharic version of the EORTC QLQ-C30 and EORTC QLQ-BR23 modules are valid and adequately reliable tool and can be used for clinical and epidemiological cancer researches to study the health related quality of life (HRQoL) of women with breast cancer in Ethiopia.

Validation of the Polish version of the EORTC QLQ-CX24 module for the assessment of health-related quality of life in women with cervical cancer

2013 ◽  
Vol 23 (2) ◽  
pp. 214-220 ◽  
Author(s):  
D. Paradowska ◽  
K.A. Tomaszewski ◽  
M. Bałajewicz-Nowak ◽  
K. Bereza ◽  
I.M. Tomaszewska ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Health Related Quality ◽  
Polish Version ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq

Health-related quality of life: validation of the Kazakh version of the EORTC QLQ-BR23 in breast cancer patients

2020 ◽  
Vol 111 (6) ◽  
Author(s):  
Almagul Zhabagina ◽  
Tasbolat Adylkhanov ◽  
Nailya Kabildina ◽  
Nurtas Tursynov ◽  
Nurlan Ibraimkhan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Breast Cancer Patients ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq

scholarly journals Health Related Quality of Life among Blood Cancer Patients in Pakistan: A Cross Sectional Survey

2021 ◽  
Vol 58 ◽  
pp. 004695802110252
Author(s):  
Madeeha Malik ◽  
Ifrah Rizwan ◽  
Azhar Hussain
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Blood Cancer ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Health Related ◽  
Eortc Qlq

The importance of health-related quality of life and its determinants including physical, emotional, and functional domains has long been recognized among blood cancer patients in the developed world but this concept is still in infancy in developing countries, including Pakistan. The objective of the study was to assess health related quality of life among blood cancer patients. A descriptive cross-sectional study design was used. A pre-validated questionnaire that is EORTC-QLQ-C30 was self-administered to a sample of 400 blood cancer patients selected using convenience sampling technique. After data collection, data was cleaned, coded, and entered in SPSS. Descriptive statistics comprising of frequency and percentages were calculated. Non-parametric tests Kruskal Wallis and Mann Whitney tests ( P ≤ .05) were performed to find out the differences among different variables. The results highlighted that lowest scores for EORTC-QLQ-C30 were observed in the domain of emotional functioning (3.38, ±35.790), followed by cognitive function (4.56, ±30.368) whereas highest scores were observed in the domain of physical functioning (40.92, ±35.484). Significant difference ( P ≤ .05) was observed among different domains of health-related quality of life of blood cancer patients treated in different sectors, provinces, setting, gender, and with different comorbidities. The present study concluded that blood cancer patients had poor health related quality of life in Pakistan. Emotional functioning and cognitive function were the most compromised health related quality of life domains among blood cancer patients. Females having blood cancer, those patients treated in private sector healthcare facilities, patients residing in tribal and rural setting had relatively better health related quality of life. No appropriate psychosocial care program for the blood cancer patients are available in Pakistan.

scholarly journals Assessment of Health Related Quality of Life Using EORTC QLQ BR-23 among Breast Cancer Patients in Pakistan

2020 ◽  
pp. 238-245
Author(s):  
Madeeha Malik ◽  
Naziha Inam ◽  
Azhar Hussain
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Breast Cancer Patients ◽  
Related Quality ◽  
Health Related ◽  
Sexual Enjoyment ◽  
Eortc Qlq

Introduction: Pakistan has the highest rate of breast cancer among all other Asian countries.Late presentation of breast cancer negatively impact health related quality of life among patients. Objective: The present study was designed to assess health related quality of life using EORTC QLQ-BR23 among patients of breast cancer in Pakistan. Methodology: A descriptive cross sectional study design was used to assess health related quality of life among 382 breast cancer patients using EORTC QLQ-BR23. Data was collected and statistically analysed using SPSS version 21. Results: The results highlighted that the lowest scores for HRQoL were observed in the domain of functional scale i.e. sexual enjoyment (7.18, ±16.84) while highest scores were observed in the domains of body image (55.82, ±29.07) followed by systemic therapy side effects (50.88, ±18.47). Conclusion: The current study concluded poor HRQoL with a negative impact on its all domains among breast cancer patients in Pakistan. Lowest scores for HRQoL were observed in the domain of functional scale i.e. sexual enjoyment and sexual functioning while, highest scores were observed in the domains of body image followed by systemic therapy side effects.

Health-related quality of life among cervical cancer patients in India

2020 ◽  
Vol 30 (12) ◽  
pp. 1887-1892 ◽  
Author(s):  
Gaurav Jyani ◽  
Akashdeep Singh Chauhan ◽  
Bhavana Rai ◽  
Sushmita Ghoshal ◽  
Radhika Srinivasan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
Health Technology ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Eq Vas ◽  
Utility Scores

IntroductionEstimation of health-related quality of life of cervical cancer patients in India is important in assessing the well-being of patients, monitor treatment outcomes, and conduct health technology assessments. However, health-related quality of life estimates for different stages of cervical cancer are not available for the Indian population. This study aims to generate stage-specific quality of life scores for cervical cancer patients in India.MethodsA cross-sectional study using the EQ-5D (EuroQol 5-dimensions) instrument, that consists of the EQ-5D-5L descriptive system and the EuroQol Visual Analog Scale (EQ-VAS) was conducted. A total of 159 cervical cancer patients were interviewed. Mean EQ-5D-5L quality of life scores (utility scores) were calculated using the EQ-5D-5L index value calculator across different stages of cervical cancer. The proportion of patients reporting problems in different attributes of EQ-5D-5L was assessed. The impact of socio-economic determinants on health-related quality of life was evaluated using multiple linear regression.ResultsThe mean EQ-5D-5L and EQ-VAS utility scores among patients of cervical cancer were 0.64 [95% CI=0.61–0.67] and 67.6 [95% CI=65.17–70.03], respectively. The most frequently reported problem among cervical cancer patients was pain/discomfort (61.88%), followed by difficulty in performing usual activities (53.81%), and anxiety/depression (41.26%).ConclusionCervical cancer significantly impacts the health-related quality of life of the patients in India. Clinical interventions should focus on the control of pain and relief of anxiety. The measurement of health-related quality of life should be an integral component of the effectiveness of interventions as well as health technology assessment.

scholarly journals Patient-Reported Outcomes of Colorectal Cancer Patients in University Malaya Medical Centre

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 102s-102s
Author(s):  
B.A. Magaji ◽  
F.M. Moy ◽  
C.W. Law ◽  
A.C. Roslani
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients ◽  
Malaysian Chinese

Background: In Malaysia, colorectal cancer is ranked the second most frequent cancer among men and women. Despite that, research on patient-reported outcomes in colorectal cancer is scarce. Aim: This study aimed to determine the pattern and factors affecting health-related quality of life (HRQOL) among colorectal cancer patients treated at the University Malaya Medical Centre (UMMC), Malaysia. Methods: This study is a cross sectional assessment of health-related quality of life of colorectal cancer patients attending UMMC using locally validated Bahasa Malaysia (BM) and Malaysian Chinese versions of the EORTC QLQ-C30 core and colorectal cancer specific EORTC-QLQ-CR29 tools. Data were drawn from patients' records, national registration department and interviews (physical and telephone). Statistical analyses included descriptive, psychometric evaluations and stepwise multiple linear regression models. Results: The reliability and validity of the BM and Malaysian Chinese tools were examined among 189 patients. The questionnaires were acceptable to the patients, with adequate Cronbach's alpha in all but the cognitive function scale, test-retest coefficient were adequate, and all items fulfilled the criteria for convergent and discriminant validity except question number 5 in QLQ-C30 in both the tools. Three hundred and twenty patients not involved in the validation study were surveyed and these patients rated their global health status/quality of life (GHS/QOL) and functional well-being higher than the EORTC reference values and reported fewer symptoms. Ethnicity was associated with the GHS/QOL at univariate level only. Role, social/family functioning scales were the two independent predictors of GHS/QOL and both are modifiable. Conclusion: Proactive engagement of patients to share their experiences with colorectal cancer and its treatment is recommended. Emphasis should be role, social and family functions, which were found to be proxies for the overall GHS/QOL.

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