A novel case of ocular cicatricial pemphigoid induced by levamisole-adulterated cocaine

2021 ◽  
Vol 31 (1_suppl) ◽  
pp. 11-15
Author(s):  
Chinedu N Igwe ◽  
Fiona Robinson ◽  
Sophie M Jones

Aim: To report a case of ocular cicatricial pemphigoid caused by levamisole-adulterated cocaine. Methods: Case report. Results: A 54-year-old woman with multi-systemic levamisole-induced vasculitis which triggered bilateral cicatrizing conjunctivitis refractory to conventional immunosuppressants due to continued cocaine misuse. Conclusion: Levamisole-induced vasculitis is a significant public health issue due to its popularity as an adulterant to cocaine. Our report suggests that levamisole caused vasculitis and ocular cicatricial pemphigoid in this case. Ocular manifestation of this syndrome is rare.

2019 ◽  
Vol 3 (4) ◽  
pp. 250-252 ◽  
Author(s):  
David M Hille

ObjectiveTo identify changes in the linear trend of the age-standardized incidence of melanoma in Australia for all persons, males, and females. MethodsA two-piece piecewise linear regression was fitted to the data. The piecewise breakpoint varied through an iterative process to determine the model that best fits the data.ResultsStatistically significant changes in the trendof the age-standardized incidence of melanoma in Australia were found for all persons, males, and females. The optimal breakpoint for all persons and males was at 1998. For females, the optimal breakpoint was at 2005. The trend after these breakpoints was flatter than prior to the breakpoints, but still positive.ConclusionMelanoma is a significant public health issue in Australia. Overall incidence continues to increase. However, the rate at which the incidence is increasing appears to be decreasing.


10.19082/7636 ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 7636-7642
Author(s):  
Ismaeil Alizadeh ◽  
Mohammad Amin Gorouhi ◽  
Abbas Aghaei Afshar ◽  
Abedin Iranpour

2016 ◽  
Vol 22 (Suppl 2) ◽  
pp. A147.2-A147
Author(s):  
Ivana Brkic Bilos ◽  
Maja Silobrcic Radic ◽  
Verica Kralj ◽  
Tanja Coric

2009 ◽  
Vol 5 (5) ◽  
pp. 497-502 ◽  
Author(s):  
Amie Williams-Frame ◽  
Janet S Carpenter

Hot flashes are the cardinal symptom of menopause and can be treated with hormonal and nonhormonal prescription medications. However, considering that 6000 women enter menopause daily in the USA, and many of these women are symptomatic, the costs of these treatments can be a significant public health issue. We evaluated annual individual and population costs of hormonal and nonhormonal prescription treatments for hot flashes. Cost information may be helpful to clinicians and consumers in making treatment decisions.


2015 ◽  
Vol 87 (7) ◽  
Author(s):  
Wiktor Meissner ◽  
Łukasz Krokowicz ◽  
Adam Bobkiewicz ◽  
Michał Drews

AbstractObesity, a major public health issue of the 21


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