Systemic Allergic Contact Dermatitis After Formaldehyde-Containing Influenza Vaccination

2015 ◽  
Vol 19 (5) ◽  
pp. 504-506 ◽  
Author(s):  
L. Alexandra Kuritzky ◽  
Melanie Pratt
Keyword(s):  
Contact Dermatitis ◽  
Influenza Vaccine ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Review Of The Literature ◽  
Cutaneous Eruption ◽  
Search Terms ◽  
Pubmed Search ◽  
Systemic Contact Dermatitis ◽  
Allergic Contact

Background: Systemic contact dermatitis occurs when a patient sensitized to an allergen topically is systemically reexposed to the allergen and develops a cutaneous eruption. Objective: To report the case of a 48-year-old male who developed explosive dermatitis following injection of a formaldehyde-containing influenza vaccine and was subsequently shown to be strongly positive to formaldehyde and formaldehyde-releasing allergens by patch testing, as well as to review the literature for similar cases. Methods: A PubMed search was made using the following search terms: systemic contact dermatitis, formaldehyde, influenza, and vaccine. Results: A review of the literature revealed 2 cases of systemic contact dermatitis from formaldehyde derived from aspartame and 1 case from a thimerosal-containing influenza vaccine. No cases caused by formaldehyde in influenza or other vaccines were found. Conclusion: This case highlights the importance of considering systemic allergic contact dermatitis in any patient presenting with dermatitis following injection of a formaldehyde-containing vaccine.

scholarly journals Metal Allergy and Systemic Contact Dermatitis: An Overview

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Yoko Yoshihisa ◽  
Tadamichi Shimizu
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Metal Allergy ◽  
Cobalt Chromium ◽  
Peripheral Blood Mononuclear ◽  
Nickel Cobalt ◽  
Systemic Contact Dermatitis ◽  
Allergic Contact

Contact dermatitis is produced by external skin exposure to an allergen, but sometimes a systemically administered allergen may reach the skin and remain concentrated there with the aid of the circulatory system, leading to the production of systemic contact dermatitis (SCD). Metals such as nickel, cobalt, chromium, and zinc are ubiquitous in our environment. Metal allergy may result in allergic contact dermatitis and also SCD. Systemic reactions, such as hand dermatitis or generalized eczematous reactions, can occur due to dietary nickel or cobalt ingestion. Zinc-containing dental fillings can induce oral lichen planus, palmoplantar pustulosis, and maculopapular rash. A diagnosis of sensitivity to metal is established by epicutaneous patch testing and oral metal challenge with metals such as nickel, cobalt, chromium, and zinc.In vitrotests, such as the lymphocyte stimulating test (LST), have some advantages over patch testing to diagnose allergic contact dermatitis. Additionally, the determination of the production of several cytokines by primary peripheral blood mononuclear cell cultures is a potentially promisingin vitromethod for the discrimination of metal allergies, including SCD, as compared with the LST.

Changes in Product Use and Quality of Life After Patch Testing in Children With Allergic Contact Dermatitis

Dermatitis ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Bruin Pollard ◽  
Reid W. Collis ◽  
Dylan Stahl ◽  
Carrie C. Coughlin ◽  
David M. Sheinbein
Keyword(s):  
Quality Of Life ◽  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Product Use ◽  
Allergic Contact

Patch testing and diagnosis when suspecting allergic contact dermatitis from medical devices

2020 ◽  
Vol 83 (4) ◽  
pp. 333-335
Author(s):  
Josefin Ulriksdotter ◽  
Martin Mowitz ◽  
Cecilia Svedman ◽  
Magnus Bruze
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Medical Devices ◽  
Patch Testing ◽  
Allergic Contact

Usefulness of Patch Testing With Patient's Own Products in the Diagnosis of Allergic Contact Dermatitis

Dermatitis ◽  
2021 ◽  
Vol 32 (1) ◽  
pp. 38-41
Author(s):  
Fátima Tous-Romero ◽  
Pablo L. Ortiz Romero ◽  
Javier Ortiz de Frutos
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Allergic Contact

Allergic Contact Dermatitis from Exotic Woods: Importance of Patch-Testing with Patient-Provided Samples

Dermatitis ◽  
2011 ◽  
Vol 22 (2) ◽  
pp. E1-E6 ◽  
Author(s):  
Joshua O. Podjasek ◽  
Robert H. Cook-Norris ◽  
Donna M. Richardson ◽  
Lisa A. Drage ◽  
Mark D.P. Davis
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Allergic Contact

Patch Testing in Vulvar Allergic Contact Dermatitis

Dermatitis ◽  
2018 ◽  
Vol 29 (2) ◽  
pp. 95-96 ◽  
Author(s):  
Megha K. Trivedi ◽  
Carina M. Woodruff ◽  
Rachel Kornik ◽  
Nina Botto
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Allergic Contact

Allergic Contact Dermatitis Secondary to Moisturizers

2020 ◽  
Vol 24 (4) ◽  
pp. 350-359
Author(s):  
Stephanie R. Cohen ◽  
Jesús A. Cárdenas-de la Garza ◽  
Paige Dekker ◽  
Wasim Haidari ◽  
Sarah S. Chisolm ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Adverse Reactions ◽  
Healthcare Providers ◽  
Standard Series ◽  
The North ◽  
Allergenic Potential ◽  
Skin Conditions ◽  
Allergic Contact

Background: Moisturizers are cosmetic products used routinely to manage various skin conditions. Even though moisturizers are often thought to have minimal or no adverse reactions, allergic contact dermatitis (ACD) to these products can develop in some cases. Methods: We studied ingredients included in 3 of the most commonly used moisturizer brands, identified their presence in standard patch testing series, and evaluated their allergenic potential, categorizing the allergens as frequent or infrequent. The standard patch testing series used as reference were the Thin-layer Rapid Use Epicutaneous patch test (T.R.U.E. test), the North American Contact Dermatitis Group (NACDG) screening standard series, and the American Contact Dermatitis Society (ACDS) core allergen series. Results: Aveeno, Cetaphil, and Cerave products had a total of 12, 14, and 9 potential allergens, respectively, the majority of which were infrequent and not included in standard patch testing series. Conclusion: Being aware of the allergenic potential of commonly used moisturizers may help healthcare providers when evaluating patients with ACD. Further testing is recommended in a targeted manner when suspecting ACD with negative standard patch testing series or when ACD is refractory to treatment.

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