African American and Caucasian Renal Transplant Recipients Have Equal Acute Rejection Rates under Sirolimus and Tacrolimus Combination Therapy

Graft ◽  
2002 ◽  
Vol 5 (8) ◽  
pp. 455-461 ◽  
Author(s):  
Rafik El-Sabrout ◽  
Veronica Delaney ◽  
Fauzia Butt ◽  
Mohamad Qadir ◽  
Pat Hanson ◽  
...  
2010 ◽  
Vol 25 (5) ◽  
pp. 721-730 ◽  
Author(s):  
Jesse D. Schold ◽  
Titte R. Srinivas ◽  
William E. Braun ◽  
Daniel A. Shoskes ◽  
Saul Nurko ◽  
...  

2008 ◽  
Vol 40 (1) ◽  
pp. 120-122 ◽  
Author(s):  
H. Karakayali ◽  
S. Pehlivan ◽  
Y. Ekici ◽  
S. Sevmis ◽  
T. Colak ◽  
...  

Author(s):  
Vural Taner Yilmaz ◽  
Ramazan Cetinkaya ◽  
Halide Akbas ◽  
Sebahat Ozdem ◽  
Burak Veli Ulger ◽  
...  

Abstract Aim: Our aim was to compare the short and long term clinical outcomes of HbsAg(+) renal transplant recipients with HbsAg(-) recipients. Patients and Methods: Two hundered and four patients who underwent renal transplantation in our center between 2001 and 2014 were included in the study. The patients were divided into two groups. Group 1: HbsAg(-) group (n=136) and Group 2: HbsAg(+) group (n=68). There was no significant difference between the groups in terms of lymphocyte cross matches, numbers of mismatches, immunosuppressive treatment protocols and induction treatments. In HbsAg(+) group, 51 patients were HBV DNA(+), 64 patients were HbeAg(-) and 4 patients were HbeAg(+). Fifty-seven (83.8%) patients were treated with Lamivudine, 4 (5.9%) patients with Entecavir and 7 (10.3%) patients with Tenofovir for Hepatitis B infection. Graft and patient survival rates, graft functions, acute hepatitis rates, acute rejection rates and other clinical outcomes of the groups were compared. Results: Demographic data and immuologic risk profiles of the groups were similar. Acute rejection rates, graft survival rates and patient survival rates were similar. Acute hepatitis rates, glomerular filtration rates on the last controls and delayed graft function rates were higher in Group 2, while chronic allograft disfunction and new onset diabetes mellitus after transplantation (NODAT) rates were similar between the groups. Conclusion: Our study revealed that, graft and patient survival and acute rejection rates were similar between HbsAg(+) and HbsAg(-) recipients, while acute hepatitis rate was higher in HbsAg(+) recipients.


2000 ◽  
Vol 69 (Supplement) ◽  
pp. S156 ◽  
Author(s):  
H. -U. Meier-Kriesche ◽  
G. S. Friedman ◽  
S. Palekar ◽  
H. Kaza ◽  
S. P. Mulgaonkar ◽  
...  

2017 ◽  
Vol 18 (4) ◽  
pp. 381-392 ◽  
Author(s):  
Qinxia Xu ◽  
Xiaoyan Qiu ◽  
Zheng Jiao ◽  
Ming Zhang ◽  
Jianping Chen ◽  
...  

1986 ◽  
Vol 32 (10) ◽  
pp. 1807-1811 ◽  
Author(s):  
K Jung ◽  
J Diego ◽  
V Strobelt ◽  
D Scholz ◽  
G Schreiber

Abstract We compared the diagnostic validity of five urinary enzymes--alanine aminopeptidase (EC 3.4.11.2), alkaline phosphatase (EC 3.1.3.1), gamma-glutamyltransferase (EC 2.3.2.2), N-acetyl-beta-D-glucosaminidase (EC 3.2.1.30), and lysozyme (EC 3.2.1.17)--as indicators of acute rejection crises in renal-transplant recipients. In 82 patients (group A), the excretion of each of these five enzymes was measured daily from transplantation until discharge from hospital. In another 69 patients (group B), enzyme determinations were made when the patient came for regular checkups (about every four to eight weeks). We used an "activity ratio" (the activity measured at a particular time compared with the activity on the preceding determination) value of 1.5 as the decision point. In group A, use of this discrimination point for alanine aminopeptidase, gamma-glutamyltransferase, and N-acetyl-beta-D-glucosaminidase yielded a specificity and sensitivity of about 90%. In group B, only alanine aminopeptidase had a greater diagnostic sensitivity than creatinine alone. Evidently, measurement of alanine aminopeptidase can be a helpful indicator of acute rejection crises, when interpreted in combination with other available relevant clinical, biochemical, and immunological data.


Sign in / Sign up

Export Citation Format

Share Document