Sigmoid Sinus Thrombosis Associated with Internal Jugular Venous Occlusion: Direct Thrombolytic Treatment

1996 ◽  
Vol 3 (3) ◽  
pp. 306-314 ◽  
Author(s):  
Melissa B. Gurley ◽  
Teresa S. King ◽  
Fong Y. Tsai
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Sinus Thrombosis ◽  
Balloon Dilation ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Sigmoid Sinus ◽  
Dural Sinus ◽  
Jugular Vein Thrombosis ◽  
Transfemoral Approach

Purpose: To report our experience with transfemoral direct venous thrombolysis and angioplasty to treat central venous and dural sinus occlusion. The cases presented are rare examples of internal jugular occlusion associated with sigmoid sinus thrombosis. Methods and Results: Two middle-aged, symptomatic female patients were diagnosed with sigmoid sinus and internal jugular vein thrombosis. Venography was performed from a contralateral transfemoral approach, followed immediately by urokinase infusion directly to the occlusion using an intermittent “burst-bolus” technique. Successful thrombolysis of the sigmoid sinus and internal jugular vein was documented in both patients. In one case, a venous stenosis was treated with balloon angioplasty. Clinical signs and symptoms resolved in both patients. Conclusions: Occluded dural sinuses and central veins can be treated with direct administration of thrombolytic agents. When an underlying stenosis is identified, balloon dilation should be used to reduce the likelihood of recurrence.

Dural Sinus Thrombosis Complicating Subclavian Vein Catheterization: Treatment With Local Thrombolysis

PEDIATRICS ◽  
1995 ◽  
Vol 95 (1) ◽  
pp. 138-140
Author(s):  
Bassam M. Gebara ◽  
Mark G. Goetting ◽  
Ay-Ming Wang
Keyword(s):  
Internal Jugular Vein ◽  
Subclavian Vein ◽  
Jugular Vein ◽  
Sinus Thrombosis ◽  
Transverse Sinus ◽  
Dural Sinus ◽  
Dural Sinus Thrombosis ◽  
Jugular Vein Thrombosis ◽  
Vein Thrombosis ◽  
Vein Catheterization

Local venous thrombosis is a known complication of subclavian vein catheterization.1,2 The clot can extend to the noncatheterized ipsilateral internal jugular vein.3,4 It is usually asymptomatic, however, signs of venous congestion can occur. Dural sinus thrombosis has been reported in association with retrograd catheterization of the internal jugular vein,5 but not the subclavian vein. We report a case of symptomatic right sigmoid sinus, transverse sinus, and bilateral internal jugular vein thrombosis without subclavian vein thrombosis in an infant few hours after placement of right subclavian vein catheter. CASE REPORT A 9-week-old girl was seen in the emergency room for lethargy, cyanosis, and apnea.

Internal jugular vein thrombosis: an uncommon presentation

Vascular ◽  
2013 ◽  
Vol 21 (4) ◽  
pp. 267-269 ◽  
Author(s):  
Sachin Mittal ◽  
Pradeep Garg ◽  
Surender Verma ◽  
Sandeep Bhoriwal ◽  
Sourabh Aggarwal
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Sinus Thrombosis ◽  
Color Doppler ◽  
Venous Catheter ◽  
Neck Surgery ◽  
Jugular Vein Thrombosis ◽  
Vein Thrombosis ◽  
Uncommon Presentation ◽  
Internal Jugular Vein Thrombosis

Internal jugular vein (IJV) thrombosis is a rare entity. It is usually secondary to various etiologies such as ovarian hyperstimulation, deep vein thrombosis of upper limbs, venous catheter, malignancy, trauma, infection, and neck surgery and hypercoagulable status. We report an unusual case of internal jugular vein thrombosis with cerebral sinus thrombosis, postpartum in a 22-year-old female patient who presented with a painful swelling on the left side of her neck. Diagnosis was established by color Doppler ultrasonography and magnetic resonance venography. Thorough evaluation of the patient revealed no etiological factor leading to thrombosis. Patient was treated with low-molecular-weight heparin.

Lemierre’s syndrome with cavernous sinus thrombosis caused by dental infection

2021 ◽  
Vol 14 (3) ◽  
pp. e238521
Author(s):  
Peerawat Sukkul ◽  
Narongrit Kasemsap
Keyword(s):  
Internal Jugular Vein ◽  
Cavernous Sinus ◽  
Jugular Vein ◽  
Sinus Thrombosis ◽  
Cavernous Sinus Thrombosis ◽  
Lemierre’S Syndrome ◽  
Jugular Vein Thrombosis ◽  
Septic Emboli ◽  
Cavernous Sinus Syndrome ◽  
Lemierre's Syndrome

Lemierre’s syndrome is a rare multisystemic infection beginning in oropharynx commonly caused by oral anaerobic organisms and leading to internal jugular vein thrombosis with septic emboli. Here, we describe a 45-year-old woman with hypertension and unrecognised type 2 diabetes who presented to a community hospital with fever, double vision and septic shock. Examination showed neck pain aggravated by neck flexion, limited ocular movement of right lateral rectus, left medial rectus and left superior oblique and incomplete ptosis of the left eye. These symptoms were suggestive of bilateral cavernous sinus syndrome. CT of the brain showed bilateral proximal internal jugular vein and cavernous sinus thrombosis. CT angiography revealed septic emboli at both upper lungs. The patient had good improvement of neurological symptoms after dental extraction, intravenous antibiotic and anticoagulant.

scholarly journals Cerebral Venous Infarction due to Internal Jugular Vein Thrombosis: A Case Study and Review of Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Iroshani Kodikara ◽  
Dhanusha Gamage ◽  
Janaka Kalubowila
Keyword(s):  
Case Report ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Sinus Thrombosis ◽  
Jugular Vein Thrombosis ◽  
Oral Contraceptive Pills ◽  
Vein Thrombosis ◽  
Venous Sinuses ◽  
Internal Jugular Vein Thrombosis ◽  
Haemorrhagic Infarction

Cerebral venous sinus thrombosis (CVST) is an uncommon disease entity. In contrast-enhanced computed tomography (CT) or magnetic resonance venography (MRV) images of the brain, CVST usually manifests as a filling defect of the dural venous sinuses. Brain parenchymal involvement in CVST can be ranged from parenchymal oedema to haemorrhagic infarctions. Though the most frequent cause of haemorrhagic infarction in brain is CVST, other rare causes such as cerebral venous outflow obstruction due to neck vein pathology have been reported. We report a rare case of haemorrhagic brain infarctions secondary to bilateral internal jugular vein thrombosis in a 17-year-old woman, who has presented with worsening headache and seizures. She had high susceptibility of getting venous thrombosis for being a young female on oral contraceptive pills. While reporting a rare cause of cerebral haemorrhagic infarctions, this case report highlights the need for having a high degree of suspicion to diagnose CVST. Further, this case report emphasises the value of prompt and adequate imaging of neck veins if the haemorrhagic infarction presents with patent cerebral venous sinuses.

scholarly journals Internal Jugular Vein Thrombosis: Etiology, Symptomatology, Diagnosis and Current Treatment

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 378
Author(s):  
Alba Scerrati ◽  
Erica Menegatti ◽  
Matilde Zamboni ◽  
Anna Maria Malagoni ◽  
Mirko Tessari ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Internal Jugular Vein ◽  
Search Strategy ◽  
Jugular Vein ◽  
Clinical Signs ◽  
Current Treatment ◽  
Central Vein ◽  
Jugular Vein Thrombosis ◽  
Vein Thrombosis ◽  
Internal Jugular Vein Thrombosis

(1) Background: internal jugular vein thrombosis (IJVthr) is a potentially life-threating disease but no comprehensive reviews on etiology, symptomatology, diagnosis and current treatment guidelines are yet available; (2) Methods: we prospectively developed a protocol that defined objectives, search strategy for study identification, criteria for study selection, data extraction, study outcomes, and statistical methodology, according to the PRISMA standard. We performed a computerized search of English-language publications listed in the various electronic databases. We also retrieved relevant reports from other sources, especially by the means of hand search in the Glauco Bassi Library of the University of Ferrara; (3) Results: using the predefined search strategy, we retrieved and screened 1490 titles. Data from randomized control trials were few and limited to the central vein catheterization and to the IJVthr anticoagulation treatment. Systematic reviews were found just for Lemierre syndrome, the risk of pulmonary embolism, and the IJVthr following catheterization. The majority of the information required in our pre-defined objectives comes from perspectives observational studies and case reports. The methodological quality of the included studies was from moderate to good. After title and abstract evaluation, 1251 papers were excluded, leaving 239 manuscripts available. Finally, just 123 studies were eligible for inclusion. We found out the description of 30 different signs, symptoms, and blood biomarkers related to this condition, as well as 24 different reported causes of IJVthr. (4) Conclusions: IJVthr is often an underestimated clinical problem despite being one of the major sources of pulmonary embolism as well as a potential cause of stroke in the case of the upward propagation of the thrombus. More common symptoms are neck pain and headache, whereas swelling, erythema and the palpable cord sign beneath the sternocleidomastoid muscle, frequently associated with fever, are the most reported clinical signs. An ultrasound of the neck, even limited to the simple and rapid assessment of the compression maneuver, is a quick, economic, cost-effective, noninvasive tool. High quality studies are currently lacking.

Direct Endovascular Thrombolytic Therapy for Dural Sinus Thrombosis

Neurosurgery ◽  
1991 ◽  
Vol 28 (1) ◽  
pp. 135-142 ◽  
Author(s):  
Stanley L. Barnwell ◽  
Randall T. Higashida ◽  
Van V. Halbach ◽  
Christopher F. Dowd ◽  
Grant B. Hieshima
Keyword(s):  
Sinus Thrombosis ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Transverse Sinus ◽  
Clinical Findings ◽  
Dural Sinus ◽  
Clot Lysis ◽  
Dural Sinus Thrombosis ◽  
Patients Âgés ◽  
Cranial Nerve Palsies

Abstract Three patients, ages 51 to 71 years, sought treatment for symptomatic dural sinus thrombosis with occlusion and were treated by direct sinus perfusion with urokinase. All three patients had a dural arteriovenous fistula; one involved the inferior petrosal sinus and two involved the transverse sinus. Clinical findings included papilledema, diminished visual acuity, decreased mentation, and cranial nerve palsies. Diagnosis was made by cerebral arteriography and confirmed by sinus venography. All three patients were treated by a transjugular direct infusion of urokinase. In one patient, a transfemoral venous approach used initially was discontinued because of an infection. The period of continuous infusion for thrombolysis ranged between 4 and 10 days. In two patients, the clinical signs and symptoms improved with angiographic evidence of clot lysis and dural sinus recanalization. Angiography indicated that one patient had a partial resolution of a clot in the torcular herophili and transverse sinus but showed no clinical improvement. These preliminary results suggest that transjugular local infusion of thrombolytic agents can be an effective treatment for symptomatic, thrombosed dural sinuses. This selective lysis avoids thrombolytic effects that could aggravate or produce systemic hemorrhagic complications.

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