scholarly journals Changes in Health-Related Quality of Life During Rehabilitation in Patients With Operable Lung Cancer: A Feasibility Study (PROLUCA)

2016 ◽  
Vol 17 (2) ◽  
pp. 388-400 ◽  
Author(s):  
Maja S. Sommer ◽  
Karen Trier ◽  
Jette Vibe-Petersen ◽  
Karl B. Christensen ◽  
Malene Missel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Well Being ◽  
Rehabilitation Program ◽  
Health Related Quality ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Health Related

Introduction: Surgical resection in patients with non–small cell lung cancer (NSCLC) may be associated with significant morbidity, functional limitations, and decreased quality of life. Objectives: The objective is to present health-related quality of life (HRQoL) changes over time before and 1 year after surgery in patients with NSCLC participating in a rehabilitation program. Methods: Forty patients with NSCLC in disease stage I to IIIa, referred for surgical resection at the Department of Cardiothoracic Surgery RT, Rigshospitalet, were included in the study. The rehabilitation program comprised supervised group exercise program, 2 hours weekly for 12 weeks, combined with individual counseling. The study endpoints were self-reported HRQoL (Functional Assessment of Cancer Therapy–Lung, European Organization for Research and Treatment in Cancer–Quality of Life Questionnaire-QLQ-C30, Short-Form-36) and self-reported distress, anxiety, depression, and social support (National Comprehensive Cancer Network Distress Thermometer, Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support), measured presurgery, postintervention, 6 months, and 1 year after surgery. Results: Forty patients were included, 73% of whom completed rehabilitation. Results on emotional well-being ( P < .0001), global quality of life ( P = .0032), and mental health component score ( P = .0004) showed an overall statistically significant improvement during the study. Conclusion: This feasibility study demonstrated that global quality of life, mental health, and emotional well-being improved significantly during the study, from time of diagnosis until 1 year after resection, in patients with NSCLC participating in rehabilitation.

scholarly journals Health-related quality of life determinants in outpatients with heart failure

2011 ◽  
Vol 19 (3) ◽  
pp. 451-457 ◽  
Author(s):  
Viviane Martinelli Pelegrino ◽  
Rosana Aparecida Spadoti Dantas ◽  
Alexander Michael Clark
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Heart Failure ◽  
Well Being ◽  
Health Related Quality ◽  
Heart Failure Care ◽  
Heart Failure Questionnaire ◽  
Related Quality ◽  
Health Related

This descriptive and exploratory study analyzed variables associated with health-related quality of life among 130 outpatients. Health-related quality of life was measured through the Minnesota Living with Heart Failure Questionnaire. Significant associations were found between patients’ health-related quality of life and their age (r=-0.177; p=0.044), vitality (r=-0.625; p=<0.001) as well as mental health (r=-0.672; p=<0.001), which are both SF-36 domains. The linear regression showed that heart failure symptom severity, vitality and mental health explained 54% of HRQOL measurement variation. To control symptoms and preserve good mental well-being are important to maintain health-related quality of life and to deliver effective heart failure care.

Health-Related Quality of Life in Men With Metastatic Prostate Cancer Treated With Prednisone Alone or Mitoxantrone and Prednisone

1999 ◽  
Vol 17 (6) ◽  
pp. 1654-1654 ◽  
Author(s):  
David Osoba ◽  
Ian F. Tannock ◽  
D. Scott Ernst ◽  
Alan J. Neville
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Metastatic Prostate Cancer ◽  
Life Questionnaire ◽  
Health Related Quality ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Health Related

PURPOSE: A combination of mitoxantrone plus prednisone is preferable to prednisone alone for reduction of pain in men with metastatic, hormone-resistant, prostate cancer. The purpose of this study was to assess the effects of these treatments on health-related quality of life (HQL). PATIENTS AND METHODS: Men with metastatic prostate cancer (n = 161) were randomized to receive either daily prednisone alone or mitoxantrone (every 3 weeks) plus prednisone. Those who received prednisone alone could have mitoxantrone added after 6 weeks if there was no improvement in pain. HQL was assessed before treatment initiation and then every 3 weeks using the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (EORTC QLQ-C30) and the Quality of Life Module–Prostate 14 (QOLM-P14), a trial-specific module developed for this study. An intent-to-treat analysis was used to determine the mean duration of HQL improvement and differences in improvement duration between groups of patients. RESULTS: At 6 weeks, both groups showed improvement in several HQL domains, and only physicalfunctioning and pain were better in the mitoxantrone-plus-prednisone group than in the prednisone-alone group. After 6 weeks, patients taking prednisone showed no improvement in HQL scores, whereas those taking mitoxantrone plus prednisone showed significant improvements in global quality of life (P = .009), four functioning domains, and nine symptoms (.001 < P < .01), and the improvement (> 10 units on a scale of 0 to100) lasted longer than in the prednisone-alone group (.004 < P < .05). The addition of mitoxantrone to prednisone after failure of prednisone alone was associated with improvements in pain, pain impact, pain relief, insomnia, and global quality of life (.001 < P < .003). CONCLUSION: Treatment with mitoxantrone plus prednisone was associated with greater and longer-lasting improvement in several HQL domains and symptoms than treatment with prednisone alone.

scholarly journals Child self-report and child-parent agreement regarding health-related quality of life under COVID-19 lockdown in the French Grand Est area

2021 ◽  
Author(s):  
Stephanie Bourion-Bedes ◽  
Hélène Rousseau ◽  
Martine Batt ◽  
Pascale Tarquinio ◽  
Romain Lebreuilly ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Social Support ◽  
Age Differences ◽  
Well Being ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Sex And Age Differences

Abstract Purpose: Billions of children worldwide were sent under lockdown due to the coronavirus disease. This study aimed to investigate child-reported and parent-rated health-related quality of life among 8- to 18-year-olds and the agreement between the children’s assessments and those of their parents during lockdown.Methods: A cross-sectional study was conducted among French children living in the Grand Est area. An online survey was used to collect data on the children’s sociodemographics, living environments, education and HRQoL. The latter was assessed with KIDSCREEN-27, which consists of five domains. Sex and age differences in parent ratings and child-reported data were analyzed using Kruskal-Wallis tests. Child-parent agreement was analyzed using the intraclass correlation coefficient (ICC).Results: In total, 471 child-parent pairs from 341 households were included. Compared to European norms, children scored lower on all dimensions during the first lockdown: physical well-being (45.9/49.94 EU), psychological well-being (48.8/49.77 EU), parent relations and autonomy (47.7/49.99 EU), social support and peers (36.4/49.94) and school (48.2/50). Significant child-reported sex and age differences were identified for both psychological and physical well-being dimensions. Moderate to good agreement existed between children’s and parents’ ratings on all KIDSCREEN dimensions (ICC ranged from 0.60 to 0.76).Conclusion: The study suggests the need to focus on children’s social support and peers during epidemics and to consider the children’s self-reported HRQoL. Additional research should be conducted to identify ways of minimizing the gap between mental health needs and the services available and to help more children maintain their physical and mental health during the current crisis.

Efficacy of an adaptive kayaking intervention for improving health-related quality of life among wounded, ill, and injured service members

2013 ◽  
Vol 12 (3) ◽  
pp. 8-16
Author(s):  
Matthew R. Scherer, PT, PhD, NCS ◽  
Daniel M. Gade, PhD ◽  
Kathleen E. Yancosek, PhD, OTR/L, CHT
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Behavioral Health ◽  
Statistical Significance ◽  
Well Being ◽  
Service Members ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Adaptive sports are popular within military and civilian rehabilitation communities as a means to promote fitness, independence, self-efficacy, and return to participation in life roles. Although widely prescribed, there is little evidence to demonstrate the efficacy of such interventions. This study surveyed 40 wounded, ill, and injured active duty and veteran service members (SMs) who participated in a week-long adaptive kayaking program. Validated health-related quality of life instruments assessing physical and behavioral health domains following trauma were administered before and after participation in a week-long adaptive kayaking trip. Postintervention analysis of these measures revealed clinically significant improvements in depression (+7 percent), anxiety (+5 percent), posttraumatic stress disorder (+4 percent), and social interaction (+7 percent) subscales on the Trauma Outcome Profile (TOP) which trended toward, but did not achieve, statistical significance. Analysis of Veterans RAND (VR-12) data revealed a mean four-point improvement in participant mental health component summary (MCS) scores (p _ 0.05) following intervention indicating clinically and statistically significant improvement in behavioral health symptoms. No improvement was observed on the mean postintervention physical health component summary (PCS) score suggesting minimal short-term effects of kayaking on self-assessment of physical well-being. In aggregate, findings from this study suggest that adaptive kayaking may be an effective intervention to remediate behavioral health sequelae commonly experienced by SM following trauma. Future research should explore the effectiveness of adaptive kayaking relative to standard of care clinical rehabilitation strategies to optimize physical as well as mental health outcomes.

scholarly journals Health-Related Quality of Life and Mental Health of Adolescents Involved in School Bullying and Homophobic Verbal Content Bullying

2019 ◽  
Vol 16 (14) ◽  
pp. 2622 ◽  
Author(s):  
Natalia Albaladejo-Blázquez ◽  
Rosario Ferrer-Cascales ◽  
Nicolás Ruiz-Robledillo ◽  
Miriam Sánchez-SanSegundo ◽  
Manuel Fernández-Alcántara ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Well Being ◽  
School Bullying ◽  
Depression And Anxiety ◽  
Health Related Quality ◽  
Homophobic Bullying ◽  
Related Quality ◽  
Health Related

Bullying has been traditionally related to a significant reduction in well-being and Health-Related Quality of Life (HRQoL) of adolescents. This negative impact on HRQoL seems to be modulated by the developed role in bullying (uninvolved, bully, victim or bully-victim). However, no studies have identified if these negative results are the same when other types of bullying, such as homophobic bullying, are evaluated. The main aim of the present study was to analyze the prevalence of different roles of bullying and homophobic bullying and the relationship between these roles in both types of bullying with HRQoL, depression and anxiety levels in a sample of 1723 Spanish adolescents. Although results exhibited lower prevalence of homophobic bullying roles when compared to traditionally bullying in general, in the case of victims, the prevalence was high in the case of homophobic bullying. When differences between roles in HRQoL, depression and anxiety were evaluated, in both types of bullying, uninvolved adolescents showed the best results and bully-victim adolescents the worst. The obtained results suppose an improvement in the understanding of the negative effects of different types of bullying on HRQoL and mental health in adolescents. Future research could advance in this comprehension, analyzing possible differences with other types of bullying, such as cyberbullying.

scholarly journals Health-related quality of life among cardiovascular patients enrolled in adult cardiology clinic in a tertiary hospital

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
EJ Pedreso ◽  
L Alamban ◽  
B Faderan
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Cardiac Rehabilitation ◽  
Physical Health ◽  
Rehabilitation Program ◽  
Health Related Quality ◽  
Related Quality ◽  
Cardiology Clinic ◽  
Health Related

Abstract Funding Acknowledgements Type of funding sources: None. Background Determining the level of health-related quality of life among cardiovascular patients and looking into the demographic factors and clinical characteristics that might influence the dynamics of their physical and mental health are highly essential for health practitioners to improve current management procedures and interventions. Objective The study was conducted to evaluate the level of health-related quality of life among cardiac patients seen in adult cardiology clinic.  Methods This study used a descriptive research design. A total of 117 cardiac patients at the adult Cardiology Clinic in a Tertiary Hospital were interviewed using the MOS-SF – 36 Questionnaire. Statistical correlation analysis was then performed. Results The results showed that the patients are challenged in their physical functioning and general mental health with an average score of 33.33 ± 33.33 aside from their average median score of 55 ± 0.0 in  their role limitations due to physical health. In terms of mental health, higher score was reflected for vitality (75 ± 12.5), followed by emotional well-being (67.5 ± 20.0). Demographic and clinical factors that affect their quality of life were also determined. Marital status, family income, educational attainment and participation on cardiac rehabilitation program affect their quality of life. Married, income above Php10,000, college level, college graduate or with post graduate degree and those who participated in the cardiac rehabilitation program have higher level of physical health (W = 1127; p=.007; W = 1729.5; p=.024; W = 1300; p=.043).  Consistently, those who are married, a family income of above Php10,000 and are aware on cardiac rehabilitation  have higher level of mental health (W = 1189; p=.019; W = 1895; p=.001; W = 1187; p=.005). Although not statistically significant, an increase in age is associated with decrease in the physical health (r=-.176; p=.058). It should not also be discounted that those patients who are employed have higher level of physical health than those who were unemployed (W = 1729.5; p=.052). Moreover, health change are higher for those who participated in the cardiac rehabilitation program (W = 960; p=.003). On clinical characteristics, those who underwent interventions have higher level of health change than those who only received medical management (W = 100.0; p&lt;.001). Mental health was also seen to be higher in those patients with no history of smoking and with &gt;40% left ventricular ejection fraction (W = 264.5; p=.005). Conclusion This study concludes that those patients who are married, employed, with income above Php10,000, who have higher educational status, non-smoker,  LVEF of more than 40%, who received interventions and who underwent cardiac rehabilitation have higher level of quality of life.

scholarly journals Associations of resilience with quality of life levels in adults experiencing homelessness and mental illness: a longitudinal study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Cilia Mejia-Lancheros ◽  
Julia Woodhall-Melnik ◽  
Ri Wang ◽  
Stephen W. Hwang ◽  
Vicky Stergiopoulos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Mental Illness ◽  
Housing First ◽  
Life Outcomes ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Health Related

Abstract Background Homelessness constitutes a traumatic period that adversely impacts health and quality of life outcomes. The potential mitigating effects of resilience on quality of life levels in people experiencing homelessness are underresearched. This study assesses the longitudinal associations between resilience and quality of life scores among adults experiencing homelessness and mental illness. Methods This study is a secondary analysis of longitudinal data collected over 6 years from participants (N = 575) of the At Home/Chez Soi study on Housing First, Toronto site. Repeatedly measured resilience scores are the primary exposure and repeatedly measured global quality of life scores and mental health-specific quality of life scores are the primary outcomes. Mixed effect models were used to assess the association between the exposures and the outcomes. Results The majority of the participants were men (69.2%) and were on average 40.4 (± 11.8) years old at baseline. The average resilience score ranged between 5.00 to 5.62 over 8 data collection points across the 6-year follow-up period. After adjusting for gender, age, ethno-racial background, Housing First intervention, physical and mental comorbidities, and lifetime homelessness, higher resilience scores were positively associated with higher Global quality of life (Adjusted-coefficient: 0.23, 95% CI 0.19–0.27) and mental health-related quality of life values (Adjusted-coefficient: 4.15, 95% CI 3.35–4.95). Conclusion In homeless adults with mental illness, higher resilience levels were positively associated with higher global and mental health related quality of life values. Further interventions and services aimed to enhance resilience mechanisms and strategies are warranted to enhance better mental health and quality of life outcomes of this population group. Trial registration At Home/Chez Soi trial was registered with ISRCTN, ISRCTN42520374. Registered 18 September 2009, http://www.isrctn.com/ISRCTN42520374.

scholarly journals The influence of a gluten-free diet on health-related quality of life in individuals with celiac disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fahdah F. Al-sunaid ◽  
Maha M. Al-homidi ◽  
Rawan M. Al-qahtani ◽  
Reema A. Al-ashwal ◽  
Ghada A. Mudhish ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Celiac Disease ◽  
Well Being ◽  
Gluten Free ◽  
Health Related Quality ◽  
Health Domains ◽  
Related Quality ◽  
Health Related

Abstract Background Adherence to a gluten-free diet (GFD) and food insecurity (FI) may influence health-related quality of life (HRQOL) in individuals with celiac disease (CD). This study aimed to investigate the association between adherence to a GFD, FI, and HRQOL in individuals with CD. Methods This cross-sectional study included 97 adults (mean age: 34 ± 9 years) diagnosed with CD. The participants were on a GFD for more than 6 months. Sociodemographic characteristics and medical history were assessed. Adherence to a GFD, FI, and HRQOL were assessed using validated questionnaires. Results Most participants (73%) adhered to a GFD, and 62% were experiencing FI. Individuals with CD faced difficulty in accessing GF foods due to the high cost (90%) and limited availability (79%). The mean overall HRQOL score was 60. Scores on the physical and mental health domains were 69 and 47, respectively. Adherence to a GFD was significantly associated with FI (P = 0.02), while there was no association between adherence to a GFD and HRQOL measures (P > 0.05). Participants facing FI had lower scores in emotional well-being and mental health domains, and overall HRQOL (P < 0.05). Conclusions The findings of the present study demonstrate that FI influences adherence to a GFD, and that FI is associated with HRQOL in terms of both emotional well-being and mental health.

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