scholarly journals Associations of resilience with quality of life levels in adults experiencing homelessness and mental illness: a longitudinal study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Cilia Mejia-Lancheros ◽  
Julia Woodhall-Melnik ◽  
Ri Wang ◽  
Stephen W. Hwang ◽  
Vicky Stergiopoulos ◽  
...  

Abstract Background Homelessness constitutes a traumatic period that adversely impacts health and quality of life outcomes. The potential mitigating effects of resilience on quality of life levels in people experiencing homelessness are underresearched. This study assesses the longitudinal associations between resilience and quality of life scores among adults experiencing homelessness and mental illness. Methods This study is a secondary analysis of longitudinal data collected over 6 years from participants (N = 575) of the At Home/Chez Soi study on Housing First, Toronto site. Repeatedly measured resilience scores are the primary exposure and repeatedly measured global quality of life scores and mental health-specific quality of life scores are the primary outcomes. Mixed effect models were used to assess the association between the exposures and the outcomes. Results The majority of the participants were men (69.2%) and were on average 40.4 (± 11.8) years old at baseline. The average resilience score ranged between 5.00 to 5.62 over 8 data collection points across the 6-year follow-up period. After adjusting for gender, age, ethno-racial background, Housing First intervention, physical and mental comorbidities, and lifetime homelessness, higher resilience scores were positively associated with higher Global quality of life (Adjusted-coefficient: 0.23, 95% CI 0.19–0.27) and mental health-related quality of life values (Adjusted-coefficient: 4.15, 95% CI 3.35–4.95). Conclusion In homeless adults with mental illness, higher resilience levels were positively associated with higher global and mental health related quality of life values. Further interventions and services aimed to enhance resilience mechanisms and strategies are warranted to enhance better mental health and quality of life outcomes of this population group. Trial registration At Home/Chez Soi trial was registered with ISRCTN, ISRCTN42520374. Registered 18 September 2009, http://www.isrctn.com/ISRCTN42520374.

2016 ◽  
Vol 17 (2) ◽  
pp. 388-400 ◽  
Author(s):  
Maja S. Sommer ◽  
Karen Trier ◽  
Jette Vibe-Petersen ◽  
Karl B. Christensen ◽  
Malene Missel ◽  
...  

Introduction: Surgical resection in patients with non–small cell lung cancer (NSCLC) may be associated with significant morbidity, functional limitations, and decreased quality of life. Objectives: The objective is to present health-related quality of life (HRQoL) changes over time before and 1 year after surgery in patients with NSCLC participating in a rehabilitation program. Methods: Forty patients with NSCLC in disease stage I to IIIa, referred for surgical resection at the Department of Cardiothoracic Surgery RT, Rigshospitalet, were included in the study. The rehabilitation program comprised supervised group exercise program, 2 hours weekly for 12 weeks, combined with individual counseling. The study endpoints were self-reported HRQoL (Functional Assessment of Cancer Therapy–Lung, European Organization for Research and Treatment in Cancer–Quality of Life Questionnaire-QLQ-C30, Short-Form-36) and self-reported distress, anxiety, depression, and social support (National Comprehensive Cancer Network Distress Thermometer, Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support), measured presurgery, postintervention, 6 months, and 1 year after surgery. Results: Forty patients were included, 73% of whom completed rehabilitation. Results on emotional well-being ( P < .0001), global quality of life ( P = .0032), and mental health component score ( P = .0004) showed an overall statistically significant improvement during the study. Conclusion: This feasibility study demonstrated that global quality of life, mental health, and emotional well-being improved significantly during the study, from time of diagnosis until 1 year after resection, in patients with NSCLC participating in rehabilitation.


2019 ◽  
Vol 70 (12) ◽  
pp. 1101-1109 ◽  
Author(s):  
Peter C. Lam ◽  
Dolly A. John ◽  
Hanga Galfalvy ◽  
Carol Kunzel ◽  
Roberto Lewis-Fernández

1999 ◽  
Vol 17 (6) ◽  
pp. 1654-1654 ◽  
Author(s):  
David Osoba ◽  
Ian F. Tannock ◽  
D. Scott Ernst ◽  
Alan J. Neville

PURPOSE: A combination of mitoxantrone plus prednisone is preferable to prednisone alone for reduction of pain in men with metastatic, hormone-resistant, prostate cancer. The purpose of this study was to assess the effects of these treatments on health-related quality of life (HQL). PATIENTS AND METHODS: Men with metastatic prostate cancer (n = 161) were randomized to receive either daily prednisone alone or mitoxantrone (every 3 weeks) plus prednisone. Those who received prednisone alone could have mitoxantrone added after 6 weeks if there was no improvement in pain. HQL was assessed before treatment initiation and then every 3 weeks using the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (EORTC QLQ-C30) and the Quality of Life Module–Prostate 14 (QOLM-P14), a trial-specific module developed for this study. An intent-to-treat analysis was used to determine the mean duration of HQL improvement and differences in improvement duration between groups of patients. RESULTS: At 6 weeks, both groups showed improvement in several HQL domains, and only physicalfunctioning and pain were better in the mitoxantrone-plus-prednisone group than in the prednisone-alone group. After 6 weeks, patients taking prednisone showed no improvement in HQL scores, whereas those taking mitoxantrone plus prednisone showed significant improvements in global quality of life (P = .009), four functioning domains, and nine symptoms (.001 < P < .01), and the improvement (> 10 units on a scale of 0 to100) lasted longer than in the prednisone-alone group (.004 < P < .05). The addition of mitoxantrone to prednisone after failure of prednisone alone was associated with improvements in pain, pain impact, pain relief, insomnia, and global quality of life (.001 < P < .003). CONCLUSION: Treatment with mitoxantrone plus prednisone was associated with greater and longer-lasting improvement in several HQL domains and symptoms than treatment with prednisone alone.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S877-S877
Author(s):  
Anjana Muralidharan ◽  
Clayton H Brown ◽  
Richard W Goldberg

Abstract Older adults with serious mental illness (i.e., schizophrenia spectrum disorders and affective psychoses) exhibit marked impairments across medical, cognitive, and psychiatric domains. The present study examined predictors of health-related quality-of-life and mental health recovery in this population. Participants (N=211) were ages 50 and older with a chart diagnosis of serious mental illness and a co-occurring medical condition, engaged in outpatient mental health services at a study site. Participants completed a battery of assessments including subtests from the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), the 24-Item Behavior and Symptom Identification Scale (BASIS-24), the 12-Item Short-Form Health Survey (SF-12), and the Maryland Assessment of Recovery Scale (MARS). Multiple linear regression analyses, with age, race, gender, and BMI as covariates, examined number of current medical conditions, RBANS, and BASIS as predictors of quality-of-life and recovery. Significant predictors of physical health-related quality-of-life (R-squared=.298, F(9,182)=8.57, p&lt;.0001) were number of medical conditions (β=-1.70, p&lt;.0001), BASIS-Depression/Functioning (β=-4.84, p&lt;.0001), and BASIS-Psychosis (β=2.39, p&lt;.0008). Significant predictors of mental health-related quality-of-life (R-squared=.575, F(9,182)=27.37, p&lt;.0001) were RBANS (β=0.03, p=.05), BASIS-Depression/Functioning (β=-6.49, p&lt;.0001), BASIS-Relationships (β=-3.17, p&lt;.0001), and BASIS-Psychosis (β=-1.30, p=.03). Significant predictors of MARS (R-squared=.434, F(9,183)=15.56, p&lt;.0001) were BASIS-Depression/Functioning (β=-4.68, p=.002) and BASIS-Relationships (β=-9.44, p&lt;.0001). To promote holistic recovery among older adults with serious mental illness, integrated interventions are required. For example, to improve physical health-related quality-of-life, one should target depression and psychotic symptoms as well as medical illness burden. To improve mental health-related quality-of-life, depression symptoms and interpersonal functioning may be key targets, as well as neurocognitive function.


Author(s):  
Nicolaas Martens ◽  
Marianne Destoop ◽  
Geert Dom

It is well established that persons with a severe mental illness (SMI) have a greater risk of physical comorbid conditions and premature mortality. Most studies in the field of community mental health care (CMHC) have only focused on improving cardiovascular health in people with a SMI using lifestyle approaches. Studies using organizational modifications are rather scarce. This systematic review aimed to synthesize and describe possible organizational strategies to improve physical health for persons with a SMI in CMHC. The primary outcome was Health-related Quality of Life (HR-QOL). Results suggested modest effects on quality of life and were inconsistent throughout all the included studies. Despite these findings, it appears that a more integrated approach had a positive effect on health outcomes, patient satisfaction and HR-QOL. The complexity of the processes involved in community care delivery makes it difficult to compare different models and organizational approaches. Mental health nurses were identified as possible key professionals in care organization, but no clear description of their role was found. This review could provide new insights into contributing factors for integrated care. Future research targeting the identification of the nurses’ role and facilitating factors in integrated care, in order to improve treatment and follow-up of somatic comorbidities, is recommended.


2021 ◽  
Vol 12 ◽  
Author(s):  
Alina Radicke ◽  
Marlit Sell ◽  
Bonnie Adema ◽  
Anne Daubmann ◽  
Reinhold Kilian ◽  
...  

Purpose: Health-related quality of life (HRQoL) can be reduced in parents with mental illness (mental illness) who face the dual demands of disabling symptoms and their impact on family, social, and occupational life. This study aimed at analyzing the influence of various factors on HRQoL in parents with mental illness.Method: Baseline data of the German randomized controlled multicenter project CHIMPS (children of parents with mental illness) was used for analyses. The final sample consisted of n = 208 parents with mental illness and n = 197 children and adolescents aged 8–18 years. HRQoL was assessed with the EQ-5D.Results: Parents with mental illness reported significantly lower global and specific HRQoL than the German reference population. They were least satisfied with aspects that relate to anxiety and depression followed by usual activities, pain and discomfort. Better global HRQoL was primarily associated with self-reported physical and mental health, as well as adaptive coping behavior. Associations with mobility, self-care, usual activity, pain and discomfort, anxiety and depression were analyzed and discussed.Conclusions: HRQoL in parents with mental illness is reduced. Clinical interventions should focus on the alleviation of mental health symptoms and probably somatic symptoms and promote adaptive coping skills.


2015 ◽  
Vol 7 (2) ◽  
pp. 117 ◽  
Author(s):  
Amanda Wheeler ◽  
Brian McKenna ◽  
Dominic Madell ◽  
Jeff Harrison ◽  
Kate Prebble ◽  
...  

INTRODUCTION: Although people with serious mental illness (SMI) have a high prevalence of physical illness, health-related quality of life (HQoL) has not been sufficiently explored. AIM: To explore the self-reported HQoL of mental health service users in New Zealand. METHODS: Responses on the Medical Outcomes Study 36 Item Short Form (SF-36) measure of HQoL from 404 adult mental health service users in a metropolitan district health board area in New Zealand were analysed and compared to a representative sample of the general population. RESULTS: Mental health service users scored significantly lower on all eight domains of the SF-36 than the general population, the largest difference being in the role limitation — emotional domain. DISCUSSION: Being female, younger than 25, obese or overweight, or of New Zealand European/Other ethnicity were associated with poorer functioning on multiple HQoL domains. Future studies should seek to understand the factors contributing to perceptions of HQoL of mental health service users in New Zealand. KEYWORDS: Mental illness; mental health; New Zealand; quality of life; self report


Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 540-540 ◽  
Author(s):  
Lene Kongsgaard Nielsen ◽  
Mary Jarden ◽  
Christen Lykkegaard Andersen ◽  
Henrik Frederiksen ◽  
Niels Abildgaard

Abstract Introduction: Multiple myeloma (MM) patients report more symptoms and more severe symptoms than patients with other hematological malignancies, resulting in reduced health-related quality of life (HRQoL). Because survival is improving in MM patients there is an increased need for focus on HRQoL. The aim of this review was to interpret published longitudinal studies in MM patients according to a difference in HRQoL score, which is perceived as beneficial to the patient. Such criteria for minimal important differences (MID) in HRQoL score has been explored by Kvam et al (Eur J Haematol 2010, 84:345-53) and has been defined by a concensus expert panel (Cocks et al, Eur J Cancer 2012, 48:1713-21). Methods: A literature search was performed May 2016 in PubMed, Embase, PsycINFO and CINAHL. Publications with longitudinal follow-up using the EORTC QLQ-C30 instrument for HRQoL measurement of physical functioning, global quality of life, fatigue or pain were included, and evaluation of mean change from baseline was carried out according to MID as defined by Kvam, and according to minimal, medium and large changes as defined by Cocks. Results: 11 first-line, 3 consolidation, 2 maintenance, 7 relapse studies, and one population-based study were included. In general, large and medium improvements were reported during first-line treatments. During consolidation with autologous hematopoietic stem cell transplantation, temporary large deteriorations were reported, but equalization occurred with even large improvements compared to baseline reportings. Deterioration or no beneficial change in global quality of life or fatigue are reported by the MM patients during relapse treatment. HRQoL data during maintenance therapy are sparse. For summary of results, see Figure 1. Conclusions: Guidelines for interpreting HRQoL changes with definitions of MID have been developed, but consensus is missing. Improvements in HRQoL are far more likely during first-line compared to relapse treatment regimens. The background of these findings should be in focus in future studies and HRQoL measurements should be part of maintenance studies in the future. Disclosures No relevant conflicts of interest to declare.


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