Adverse Childhood Experiences as “Upstream” Determinants of Lifestyle-Related Chronic Disease: A Scoping Perspective

2021 ◽  
pp. 155982762110012
Author(s):  
Garry Egger ◽  
Andrew Binns ◽  
Bob Morgan ◽  
John Stevens
Keyword(s):  
Chronic Disease ◽  
Adverse Childhood Experiences ◽  
Health Problems ◽  
Lifestyle Medicine ◽  
Childhood Experiences ◽  
Disease Outcomes ◽  
Adverse Childhood ◽  
Chronic Disorders ◽  
Distal Disease ◽  
Upstream Determinants

We have previously proposed a list of determinants (causes) of modern lifestyle-related chronic disorders, which provides a structure for the emerging discipline of lifestyle medicine. This consists of lifestyle factors with a common immune biomarker ( metaflammation) that interact in a systems fashion linked with chronic disease outcomes. We considered this to be a work in progress and later added 3 psychosocial determinants into the causal mix: meaninglessness, alienation, and loss of culture and identity (MAL). Here, we propose adverse childhood experiences (ACEs) as deeper, or even more distal, disease drivers that may act directly or indirectly through MAL to influence later chronic disease. The links with metaflammation and the need for recognition of these embedded scars in the management of lifestyle-related health problems is discussed.

scholarly journals Parents’ Adverse Childhood Experiences and Their Children’s Behavioral Health Problems

PEDIATRICS ◽  
2018 ◽  
Vol 142 (2) ◽  
pp. e20180023 ◽  
Author(s):  
Adam Schickedanz ◽  
Neal Halfon ◽  
Narayan Sastry ◽  
Paul J. Chung
Keyword(s):  
Behavioral Health ◽  
Adverse Childhood Experiences ◽  
Health Problems ◽  
Childhood Experiences ◽  
Adverse Childhood

scholarly journals The impact of adverse childhood experiences on health problems: evidence from four birth cohorts dating back to 1900

2003 ◽  
Vol 37 (3) ◽  
pp. 268-277 ◽  
Author(s):  
Shanta R Dube ◽  
Vincent J Felitti ◽  
Maxia Dong ◽  
Wayne H Giles ◽  
Robert F Anda
Keyword(s):  
Adverse Childhood Experiences ◽  
Health Problems ◽  
Birth Cohorts ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
The Impact

Do Social Bonds Buffer the Impact of Adverse Childhood Experiences on Reoffending?

2016 ◽  
Vol 15 (1) ◽  
pp. 3-20 ◽  
Author(s):  
Jessica M. Craig ◽  
Michael T. Baglivio ◽  
Kevin T. Wolff ◽  
Alex R. Piquero ◽  
Nathan Epps
Keyword(s):  
Chronic Disease ◽  
Adverse Childhood Experiences ◽  
Social Bonds ◽  
Negative Consequences ◽  
Adjudicated Youth ◽  
Future Directions ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
The Impact ◽  
The Relationship

Research from multiple disciplines has reported that exposure to childhood traumatic events, often referred to as adverse childhood experiences (ACEs), increases an individual’s chances of experiencing a wide variety of negative consequences such as chronic disease, unemployment, and involvement in serious, violent, and chronic offending. The current study assesses how protective factors from social bonds may moderate the relationship between ACEs and future offending in a sample of high-risk adjudicated youth. While results showed that increased ACE exposure led to a higher likelihood of rearrest and more social bonds lowered the likelihood of rearrest, in contrast to expectations, the analyses revealed that stronger social bonds did not reduce the deleterious effects of exposure to more types of ACEs on recidivism. A discussion of these findings is offered, along with study limitations and future directions.

scholarly journals The Relationship of Adulthood Chronic Disease and Adverse Childhood Experiences (ACEs): Implications Regarding Prevention and Promotion in International Health

2021 ◽  
Author(s):  
Jordan Holter ◽  
Christine Marchionni ◽  
Bankim Bhatt
Keyword(s):  
Chronic Disease ◽  
Adverse Childhood Experiences ◽  
International Health ◽  
Childhood Adversity ◽  
Maladaptive Behavior ◽  
Kaiser Permanente ◽  
Childhood Experiences ◽  
Health Security ◽  
Ace Study ◽  
Adverse Childhood

Several studies, including the innovative 1998 ACE Study by CDC-Kaiser Permanente, have assessed the association among adulthood chronic disease and the prevalence of maladaptive, health-harming behaviors including: excessive alcohol use, tobacco use, physical inactivity, psychiatric illness including suicidal ideation or attempts, promiscuous sexual behavior (>50 sex partners), history of STI/STD and severe obesity (obesity (BMI > 35 kg/m2)), subsequent to an individual’s exposure to adverse childhood experiences (ACEs). Individuals that have encountered numerous instances of ACEs are almost twice as likely to die before the age of 75, demonstrating a dose-dependent relationship between the instances of ACEs and an increased morbidity/mortality in regard to chronic disease. This excerpt examines the contribution of ACEs to chronic disease and the consequential maladaptive behavior to said adversity, the consequential physiologic and biomolecular changes explained by the Biological Embedding of Childhood Adversity Model in addition to the implications of recounted ACEs on international health security in regard to concepts like conflict, displacement and food insecurity. The apparent association among adulthood chronic disease and ACEs demand changes that promote preventative processes as a means to address the implications these interconnections have on international health.

scholarly journals Adverse Childhood Experiences and Chronic Disease Risk in the Southern Community Cohort Study

2021 ◽  
Vol 32 (3) ◽  
pp. 1384-1402
Author(s):  
Maureen Sanderson ◽  
Charles P. Mouton ◽  
Mekeila Cook ◽  
Jianguo Liu ◽  
William J. Blot ◽  
...  
Keyword(s):  
Cohort Study ◽  
Chronic Disease ◽  
Adverse Childhood Experiences ◽  
Disease Risk ◽  
Childhood Experiences ◽  
Chronic Disease Risk ◽  
Adverse Childhood
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