scholarly journals A stepwise approach for pharmacists: Cardiovascular risk reduction with novel antihyperglycemic agents in patients with type 2 diabetes and atherosclerotic cardiovascular disease

Author(s):  
Logan Underwood ◽  
William Semchuk ◽  
Lori Albers
2017 ◽  
Vol 31 (4) ◽  
pp. 459-470 ◽  
Author(s):  
Scott L. Purga ◽  
Mandeep Sidhu ◽  
Michael Farkouh ◽  
Joshua Schulman-Marcus

2020 ◽  
Vol 66 (9) ◽  
pp. 1283-1288
Author(s):  
Eduardo Bello Martins ◽  
Eduardo Gomes Lima ◽  
Fábio Grunspun Pitta ◽  
Leticia Neves Solon Carvalho ◽  
Thiago Dias de Queiroz ◽  
...  

SUMMARY The pharmacological therapy for type 2 diabetes mellitus has presented important advances in recent years, which has impacted the treatment of patients with established cardiovascular disease or with high cardiovascular risk. In this scenario, two drug classes have emerged and demonstrated clear clinical benefits: SGLT-2 inhibitors and GLP-1 agonists. The present review discusses the pharmacology, adverse effects, and clinical trials that have demonstrated the benefits of these medications in reducing cardiovascular risk.


2020 ◽  
Vol 76 (9) ◽  
pp. 1117-1145 ◽  
Author(s):  
Sandeep R. Das ◽  
Brendan M. Everett ◽  
Kim K. Birtcher ◽  
Jenifer M. Brown ◽  
James L. Januzzi ◽  
...  

Author(s):  
S. V. Nedogoda

The data from a range of large trials (LEADER, EMPA-REG, CANVAS) show evidently the practical use of the modern glucose lowering drugs usage for successful management of cardiovascular risk in type 2 diabetes (DM2) patients. The article is focused on analysis and review of possible mechanisms and benefits of cardiovascular risk reduction in DM2 with prescription of the antagonist of glucagonlike peptide 1 — liraglutide (Victoza®).


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