The correlation of neurophysiological findings with clinical and functional status in patients following traumatic nerve injury

In this study, we aimed to determine whether there is a correlation between the electrodiagnostic findings and the functional status, muscle strength and sensibility in patients with traumatic nerve injury to the wrists. We assessed 50 patients at a mean of 11.6 months (SD 5.85) (range 6–25) after nerve injury. Sensibility was assessed by monofilament testing. Motor function was evaluated by assessing the manual muscle grade of the abductor pollicis brevis and abductor digiti minimi muscles. Function was evaluated by the Sollerman Hand Function Test. The amplitudes of the compound muscle action potential and the sensory nerve action potential were determined by electroneuromyography. While the compound muscle action potential and sensory nerve action potential amplitudes had significant correlation with muscle grade and Semmes Weinstein Monofilament tests, there was no correlation with the functional scores.

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Clinical predictors of surgical outcomes of severe carpal tunnel syndrome patients: utility of palmar stimulation in a nerve conduction study

BMC Musculoskeletal Disorders ◽

10.1186/s12891-020-03750-z ◽

2020 ◽

Vol 21 (1) ◽

Author(s):

Yuichi Sasaki ◽

Tohru Terao ◽

Emiko Saito ◽

Keiichiro Ohara ◽

Shotaro Michishita ◽

...

Keyword(s):

Carpal Tunnel Syndrome ◽

Action Potential ◽

Carpal Tunnel ◽

Compound Muscle Action Potential ◽

Sensory Nerve ◽

Sensory Nerve Action Potential ◽

Muscle Action ◽

Muscle Action Potential ◽

Sensory Nerve Action ◽

Tunnel Syndrome

Abstract Background Carpal tunnel syndrome is a common peripheral nerve compression disorder. However, there is no established opinion regarding the predictors of symptom improvement after surgery. This study aimed to identify the predictors of surgical outcomes of severe carpal tunnel syndrome patients. Methods In the patients who underwent a carpal tunnel syndrome surgery, we selected the patients who had a preoperative Bland’s classification of grade 5 or 6, and assessed for the changes in Bland’s classification grade before and after surgery. Those who showed improvement from preoperative grades 5–6 to postoperative grades 1–4 comprised the improvement group. In contrast, those who did not show improvement and had postoperative grades 5 or 6 comprised the non-improvement group. In a nerve conduction study, amplitudes of the compound muscle action potential and sensory nerve action potential of the palms were assessed between the improvement and non-improvement groups. Results Among the 60 hands of 46 patients who had a preoperative Bland’s classification of grade 5 or 6, 49 hands of 37 patients comprised the improvement group, and 11 hands of 9 patients comprised the non-improvement group. The amplitudes of the compound muscle action potential and sensory nerve action potential of the palms before surgery were significantly higher in the improvement group. The degree of improvement in Bland’s classification grade was correlated with the degree of clinical symptom improvement. Conclusions Amplitudes of compound muscle action potential and sensory nerve action potential before surgery induced by palmar stimulation can predict improvements in nerve conduction study scores and clinical findings after surgical treatment.

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Nerve Conduction Study in Healthy Individuals: a Gender Based Study

Health Renaissance ◽

10.3126/hren.v8i3.4210 ◽

1970 ◽

Vol 8 (3) ◽

pp. 169-175 ◽

Cited By ~ 3

Author(s):

Dilip Thakur ◽

BH Paudel ◽

BK Bajaj ◽

CB Jha

Keyword(s):

Action Potential ◽

Nerve Conduction Study ◽

Nerve Conduction ◽

Compound Muscle Action Potential ◽

Sensory Nerve ◽

Sensory Nerve Action Potential ◽

Muscle Action ◽

Muscle Action Potential ◽

Sensory Nerve Action ◽

Motor Nerves

Background: Nerve conduction study (NCS) assesses peripheral nerve functions and has clinical implication. Objective: To study effect of gender on NCS variables in healthy adults. Settings and Design: Department of Physiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal. Material and Method: The study was done in 34 (m=19, 32±11 years; f=15, 32±12 years) consenting healthy adults. The compound muscle action potential (CMAP) and sensory nerve action potential (SNAP) were recorded. Statistical analysis: The effect of gender on NCS variables was analyzed using Mann Whitney U test. Results: Male vs. female: males had increased CMAP and F-wave latencies (ms) in all tested motor nerves. CMAP duration (ms) was longer in males (p<0.05) in all tested motor nerves: right median (5.9±1.3 vs. 4.92±0.65), left median (5.54±0.91 vs. 4.72±0.57), right ulnar (5.55±1.01 vs. 4.56±0.59), left ulnar (5.71±0.97 vs. 4.64±0.51), right tibial (6.58±0.95 vs. 5.95±0.71), and left tibial (6.98±1.31 vs. 6.21±0.78). Females showed higher sural SNAP amplitude (µV) (23.26±9.23 vs. 15.94±8.42). SNAP duration (ms) was longer in males: right ulnar (1.16±0.19 vs. 1.03±0.06). SNAP latencies (ms) were also longer in males: right sural (2.61±0.44 vs. 2.21±0.36). Males had greater height (165.9±4.74 vs. 149.3±7.24) and weight (60.4±7.2 vs. 53±7.2).Conclusion: Gender has definite effects on NCS variables. Males had higher CMAP amplitude, longer latencies and duration. SNAP latencies and duration were longer in males whereas amplitude was higher in females. Without adjustment for these factors, the sensitivity and specificity of NCS will decrease when using the same reference data in patients with different gender. Keywords: compound muscle action potential; gender; nerve conduction study; sensory nerve action potential DOI: 10.3126/hren.v8i3.4210Health Renaissance, September-December 2010; Vol 8 (No.3);169-175

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Injection nerve palsy

Journal of Neurosciences in Rural Practice ◽

10.4103/0976-3147.105603 ◽

2013 ◽

Vol 04 (01) ◽

pp. 13-18 ◽

Cited By ~ 3

Author(s):

Arindhom Kakati ◽

Dhananjaya Bhat ◽

Bhagavathula Indira Devi ◽

Dhaval Shukla

Keyword(s):

Action Potential ◽

Compound Muscle Action Potential ◽

Sensory Nerve ◽

Motor Deficit ◽

Nerve Action ◽

Muscle Action Potential ◽

Sensory Nerve Action ◽

Operative Findings ◽

Case Outcome ◽

Outcome Of Surgery

ABSTRACT Objective: To study the clinical profile and outcome of surgery for injection nerve palsies. Materials and Methods: This is a retrospective study of patients with INP who were treated at our institute during May 2000 to May 2009. Clinical, electroneuromyography (ENMG), and operative findings were noted. Intraoperative nerve action potential monitoring was not used in any case. Outcome of patients who were followed was reviewed. Results: INP comprised 92 (11%) of 837 nerve injury patients. Seventy one patients were children less than 16 years. The nerves involved were sciatic in 80 patients, radial in 8, and others in four. Fifty seven patients had power, grade 0/5. ENMG studies revealed absent compound muscle action potential in 64 and absent sensory nerve action potential in 67 patients. Thirty nine (42.3%) of 92 patients underwent surgery. The mean duration since injury in these patients was 5.2 months (3 months to 11 months). All underwent neurolysis. Only 18 patients who underwent surgery had a follow up of more than 3 months. Ten (55.5%) patients had good or fair outcome after surgery. Except for grade of motor deficit prior to surgery, none of the variables were found to significantly affect the outcome. Conclusion: The outcome of INP is generally good and many patients recover spontaneously. The outcome of surgery is dependent on preoperative motor power.

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Electrophysiological diagnosis using sensory nerve action potential for the intraforaminal and extraforaminal L5 nerve root entrapment

European Spine Journal ◽

10.1007/s00586-012-2592-5 ◽

2012 ◽

Vol 22 (4) ◽

pp. 833-839 ◽

Cited By ~ 19

Author(s):

Muneharu Ando ◽

Tetsuya Tamaki ◽

Mamoru Kawakami ◽

Akihito Minamide ◽

Yukihiro Nakagawa ◽

...

Keyword(s):

Action Potential ◽

Nerve Root ◽

Sensory Nerve ◽

Sensory Nerve Action Potential ◽

Nerve Action ◽

Sensory Nerve Action ◽

Nerve Root Entrapment

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Close relationship between cardiovagal function and sural sensory nerve action potential in type 2 diabetes

Clinical Neurophysiology ◽

10.1016/j.clinph.2019.03.036 ◽

2019 ◽

Vol 130 (7) ◽

pp. 1160-1165

Author(s):

Yun-Ru Lai ◽

Chih-Cheng Huang ◽

Wen-Chan Chiu ◽

Rue-Tsuan Liu ◽

Nai-Wen Tsai ◽

...

Keyword(s):

Type 2 Diabetes ◽

Action Potential ◽

Sensory Nerve ◽

Sensory Nerve Action Potential ◽

Nerve Action ◽

Close Relationship ◽

Sensory Nerve Action

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Normal neurophysiologic parameters of the median nerve among adult healthy Sudanese population

Journal of Neurology & Stroke ◽

10.15406/jnsk.2020.10.00427 ◽

2020 ◽

Vol 10 (4) ◽

pp. 136-141

Author(s):

Mohammed Salah Elmagzoub ◽

Ahmed Hassan Ahmed ◽

Hussam M A Hameed

Keyword(s):

Action Potential ◽

Median Nerve ◽

Conduction Velocity ◽

Nerve Conduction ◽

Compound Muscle Action Potential ◽

Motor Nerve ◽

Sensory Nerve ◽

Peak Latency ◽

Muscle Action Potential ◽

Sensory Nerve Action

Background: Nerve conduction studies (NCSs) help in delineating the extent distribution of neural lesion, and the diagnosis of peripheral nerve disorders. Because normative nerve conduction parameters were not yet established in Sudan EMG laboratories, this study aims towards having our own reference values, as we are using the American and British parameters. This will allow avoiding the discrepancies that might be induced by many factors. Methods: NCSs were performed in 200 Median nerves of 100 adult healthy Sudanese subjects using standardized techniques. Results: The median SNAP (sensory nerve action potential) values were as follows: distal latency, 2.6±3 ms with a range of (2.3-2.9); peak latency, 3.5±0.5 ms (3.0-4.0); amplitude, 47.7±18.0μV (29.7-65.7); conduction velocity, 53.0±7.8 m/s (45.2-60.8). The following values were obtained for the Median nerve CMAP (compound muscle action potential) at wrist stimulation: distal latency, 3.5±0.5 ms with a range of (3.0-4.0); peak latency, 9.4± 1.0 ms (8.4-10.4); duration, 5.9±0.9 ms (5.0-6.8); amplitude, 12.3±2.5 mV (9.8-14.8); area, 43.0±10.4 mVms (32.6-53.4); conduction velocity, 63.6±6.2 m/s (57.4-69.8). The F wave was 28.4±1.8 ms (26.6-30.2). Conclusion: The overall mean sensory and motor nerve conduction parameters for the tested nerve compared favorably with the existing literature with some discrepancies that were justified.

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