scholarly journals Review of the epidemiology and burden of ulcerative colitis in Latin America

2020 ◽  
Vol 13 ◽  
pp. 175628482093173 ◽  
Author(s):  
Paulo Gustavo Kotze ◽  
Flavio Steinwurz ◽  
Carlos Francisconi ◽  
Cyrla Zaltman ◽  
Marcia Pinheiro ◽  
...  

The incidence and prevalence of ulcerative colitis (UC) has been reported to be rising in newly industrialised regions, such as Latin America. Here, we review data from published studies reporting demographics and clinical aspects of UC in Latin America to further understand epidemiology and disease burden. The incidence and prevalence of UC in Latin America varied between regions and studies, ranging between 0.04 to 8.00/100,000 and 0.23 to 76.1/100,000, respectively, and generally increased over the period from 1986 to 2015. The majority of patients with UC were female (53.6–72.6%) and urban residents (77.8–97.4%). Extraintestinal manifestations were reported in approximately 26–89.4% of patients. Use of biologic therapies was generally low (0.8–16.2%), with the exception of Mato Grosso do Sul, Brazil, with a greater proportion of patients tending to receive 5-aminosalicylates, immunosuppressants or corticosteroids; colectomy rates varied between studies (1.5–22%). A high proportion of patients had moderate to severe UC (45.9–73.0%) and, in 11 of 19 studies, the greatest proportion of patients had extensive disease (pancolitis). Colorectal cancer (0–1.7%) and mortality rates (0–7.6%) were low. This evaluation of published studies may influence therapeutic approaches and the development of strategies to improve healthcare access and patient outcomes, although further high-quality studies are required in patients with UC in Latin America.

2016 ◽  
Vol 110 (4) ◽  
pp. 228-236 ◽  
Author(s):  
Nieli Rodrigues da Costa Faria ◽  
Victor Edgar Fiestas Solorzano ◽  
Rita Maria Ribeiro Nogueira ◽  
Thaís Chouin-Carneiro ◽  
Priscila Conrado Guerra Nunes ◽  
...  

2021 ◽  
Vol 10 (12) ◽  
pp. e549101220684
Author(s):  
Lara Camila de Oliveira ◽  
Neide Martins Moreira

Objectives: To verify the number of visceral leishmaniasis (VL) cases in Brazil and its states and twin cities, with a focus on the state and twin city with the highest number of cases. We investigated social, demographic, laboratory and clinical aspects of these cases. Methodological design: We performed a descriptive study using a quantitative approach and data from 2010 to 2019 that were obtained through a public domain website, the Informatics Department of the Unified Health System. The incidence rate of VL cases was calculated per 100,000 inhabitants. software. Results: In Brazil, 35,886 VL cases were reported, with 2,834 cases in international border states and 148 cases in twin cities. The state and twin city with the highest number of cases were Mato Grosso do Sul (1,834 cases) and Corumbá (94 cases), respectively, with annual mean incidence rates of 6.4 and 8.3 cases per 100,000 inhabitants. In Mato Grosso do Sul and Corumbá, the disease was more frequent in male and brown-skinned individuals who had up to 8 years of education (age range: 1 to > 80 years old). Most of the cases occurred in urban areas, was diagnosed by laboratory tests and evolved to cure (p < 0.05). Conclusions: A high number of VL cases in Brazil was found during the period of study. The cases were distributed in 10 states with international borders and eight twin cities. These findings draw attention to the greater need for management programs to control and prevent VL.


2016 ◽  
Vol 20 (34) ◽  
pp. 154
Author(s):  
Marcos Antônio Bessa-Oliveira ◽  
Edgar Cézar Nolasco

The State of Mato Grosso do Sul, Brazil, was established and politically from the geographic division of the State of Mato Grosso in 1977. The new State assumed the title of largest producer of dairy cattle and cropping in Latin America. Since then, various artistic themes have been addressed by local art production, as it has been done throughout Latin America: the artistic cultural productions turn their heads to their rural areas. From this period of division of states, cattle prevailed routinely as the most expressive theme of art production. In this production, cattle is preserved and supported both by the government and by its co-opted critics, which keep resonances in Mato Grosso do Sul’s artistic production. Horns, leather, iconographies, hot iron brands permeate the works made by artists born and residing in the State. This article aims to investigate critically this recurrence in artistic production between the years of 1977 and 2010, a period that marked the State of Mato Grosso do Sul as a particular artistic and cultural entity member of the National Assembly, by tracking the way in which the lowland landscape of the bull is still in keep with being an “artistic relief” representing the State. Using concepts like Charles Baudelaire’s beauty, as well as Theodor W. Adorno’s Essay as form, among others, this work aims to reflect on Mato Grosso do Sul’s current, post-division artistic situation. That is, why is the bull a constant in the state’s visual arts.


2021 ◽  
Vol 15 (4) ◽  
pp. e0009317
Author(s):  
Karine Mattos ◽  
Tiago Alexandre Cocio ◽  
Edilânia Gomes Araújo Chaves ◽  
Clayton Luiz Borges ◽  
James Venturini ◽  
...  

Background Paracoccidioidomycosis (PCM) is a systemic and endemic fungal infection in Latin American, mainly in Brazil. The majority of PCM cases occur in large areas in Brazil, comprising the South, Southeast and Midwest regions, with the latter demonstrating a higher incidence of the species Paracoccidioides lutzii. Methodology and main findings This study presents clinical, molecular and serological data of thirteen new PCM cases during 2016 to 2019 from the state of Mato Grosso do Sul, located in the Midwest region, Brazil. From these thirteen cases, sixteen clinical isolates were obtained and their genomic DNAs were subjected to genotyping by tub1 -PCR-RFLP. Results showed Paracoccidioides brasiliensis sensu stricto (S1) (11/16; 68.8%), Paracoccidioides restrepiensis (PS3) (4/16; 25.0%) and P. lutzii (1/16; 6.2%) as Paracoccidiodes species. Therefore, in order to understand whether the type of phylogenetic species that are circulating in the state influence the reactivity profile of serological tests, we performed double agar gel immunodiffusion (DID), using exoantigens from genotyped strains found in this series of PCM cases. Overall, our DID tests have been false negative in about 30% of confirmed PCM cases. All patients were male, most with current or previous rural activity, with ages ranging from 17 to 59 years, with 11 patients (84.6%) over 40 years of age. No clinical or epidemiological differences were found between Paracoccidioides species. However, it is important to note that the only case of P. lutzii died as an outcome. Conclusions This study suggests P. brasiliensis sensu stricto (S1) as the predominant species, showing its wide geographic distribution in Brazil. Furthermore, our findings revealed, for the first time, the occurrence of P. restrepiensis (PS3) in the state of Mato Grosso do Sul, Brazil. Despite our setbacks, it would be interesting to provide the complete sequencing of these clinical isolates to complement the molecular information presented.


2020 ◽  
Vol 45 (2) ◽  
pp. 340-348
Author(s):  
James Lucas da Costa-Lima ◽  
Earl Celestino de Oliveira Chagas

Abstract—A synopsis of Dicliptera (Acanthaceae) for Brazil is presented. Six species are recognized: Dicliptera ciliaris, D. sexangularis, and D. squarrosa, widely distributed in South America; D. purpurascens, which ranges from the North Region of Brazil (in the state of Acre) to eastern Bolivia; D. gracilirama, a new species from the Atlantic Forest of northeastern Brazil; and D. granchaquenha, a new species recorded in dry and semideciduous forests in Bolivia and western Brazil, in the state of Mato Grosso do Sul. Furthermore, we propose new synonyms and designate lectotypes for eleven names. An identification key to the six accepted Dicliptera species in Brazil is provided.


Author(s):  
F. PERBONI ◽  
Carla Regina de Souza FIGUEIREDO ◽  
A. MARQUES ◽  
A. N. MILITÃO ◽  
C. N. JESUS ◽  
...  

2012 ◽  
Vol 11 (1) ◽  
Author(s):  
Paulo Roberto Cimo Queiroz

O espaço correspondente ao atual Estado brasileiro de Mato Grosso do Sul foi incorporado, no século XVI, aos circuitos do Paraguai colonial, mas, já no século XVII, no contexto que S. B. de Holanda denomina refluxo assuncenho, a presença espanhola foi sendo substituída pela luso-brasileira, passando, portanto, essa região a vincular-se, ainda que de m o do inicialmente tênue, ao sudeste da América portuguesa. Em meados d o século XIX, c om a liberação da navegação brasileira pelo rio Paraguai, essa região voltou, de certo modo, a fazer parte do espaço platino. O presente trabalho busca evidenciar que, a despeito das notáveis mudanças induzidas pela livre navegação, esse último período de vinculação ao espaço platino constituiu, na verdade, uma espécie de "hiato", no interior do processo mais longo, representado pela vinculação com o mercado nacional brasileiro.


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