scholarly journals Isolation, and Structural Characterization of a New Hexa β-D-Glucopyranosyl Diterpene from Stevia rebaudiana

2018 ◽  
Vol 13 (4) ◽  
pp. 1934578X1801300
Author(s):  
Venkata Sai Prakash Chaturvedula ◽  
Srinivasa Rao Meneni
Keyword(s):  
Spectral Data ◽  
Structural Characterization ◽  
Stevia Rebaudiana ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Stevia Rebaudiana Bertoni

A new diterpene glycoside with six β-D-glucopyranosyl units was isolated from the extract of the leaves of Stevia rebaudiana Bertoni, which was identified as 13-[(2- O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid-[2- O-β-D-glucopyranosyl-3- O-(2- O-β-D-glucopyranosyl)-β-D-glucopyrano-syl -β-D-glucopyranosyl) ester (1) based on the extensive NMR (1H and 13C, COSY, HSQC, and HMBC) and mass spectral data as well as hydrolysis studies.

scholarly journals New Diterpene Glycosides from Stevia rebaudiana Bertoni: Rebaudioside VIII and Rebaudioside IXd

2018 ◽  
Vol 13 (10) ◽  
pp. 1934578X1801301
Author(s):  
Gil Ma ◽  
Allison Bechman ◽  
Cynthia Bunders ◽  
Krishna P. Devkota ◽  
Romila D. Charan ◽  
...  
Keyword(s):  
Spectral Data ◽  
Stevia Rebaudiana ◽  
Steviol Glycosides ◽  
Mass Spectral Data ◽  
Complete Structure ◽  
Mass Spectral ◽  
Stevia Rebaudiana Bertoni ◽  
Rebaudioside D

With our interest of new diterpene glycosides with better taste profile than Rebaudioside M, we isolated and characterized two steviol glycosides with three additional glucose attached at the C-13 of Rebaudioside M or Rebaudioside D from an extract of Stevia rebaudiana Bertoni. Here we report the complete structure elucidations of diterpene glycosides on the basis of NMR experiments (1H, 13C, COSY, HSQC-DEPT, HMBC, 1D TOCSY, NOESY) and mass spectral data. Steviol glycosides that possess eight or nine glucose units are rarely reported in literature and could have an impact on the natural sweetener catalog.

scholarly journals Complete Structure Elucidation of New Steviol Glycosides Possessing 9 Glucose Units Isolated from Stevia rebaudiana

2017 ◽  
Vol 12 (10) ◽  
pp. 1934578X1701201 ◽  
Author(s):  
Indra Prakash ◽  
Sangphyo Hong ◽  
Gil Ma ◽  
Cynthia Bunders ◽  
Krishna P. Devkota ◽  
...  
Keyword(s):  
Spectral Data ◽  
Structure Elucidation ◽  
Stevia Rebaudiana ◽  
Steviol Glycosides ◽  
Mass Spectral Data ◽  
Complete Structure ◽  
Mass Spectral ◽  
Stevia Rebaudiana Bertoni ◽  
Glycoside Linkage

In our continued effort to discover new diterpene glycoside sweeteners from Stevia rebaudiana Bertoni with a better taste profile than that of rebaudioside M, we have isolated three novel steviol glycosides with 9 glucose units, 3 at the C-13 site of the aglycone backbone and 6 at the C-19 site. Compounds 2-4 contain an additional tri-glucosyl unit attached to the C-19 glycoside region of rebaudioside M. For compounds 2 and 3 this unit is attached via the relatively rare 1→6 α-glycoside linkage. For compound 4 this additional unit is attached via the uncommon 1→3 α-glycoside linkage. In this paper, we describe the complete structure elucidation of novel diterpene glycosides with 9 sugar moieties by NMR (1H, 13C, COSY, HSQC-DEPT, HMBC, 1D TOCSY, NOESY) and mass spectral data.

scholarly journals Isolation, Characterization and Sensory Evaluation of a Hexa β-D-Glucopyranosyl Diterpene from Stevia rebaudiana

2013 ◽  
Vol 8 (11) ◽  
pp. 1934578X1300801 ◽  
Author(s):  
Indra Prakash ◽  
Venkata Sai Prakash Chaturvedula ◽  
Avetik Markosyan
Keyword(s):  
Spectral Data ◽  
Sensory Evaluation ◽  
Nmr Assignment ◽  
Stevia Rebaudiana ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Stevia Rebaudiana Bertoni ◽  
First Time ◽  
C Nmr

From the extract of the leaves of Stevia rebaudiana Bertoni, a diterpene glycoside was isolated which was identified as 13-[(2- O-β-D-glucopyranosyl-3- O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid-(2- O-β-D-glucopyranosyl-3- O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester (1). The complete 1H and 13C NMR assignment of 1 is reported for the first time, from extensive NMR (1H and 13C, COSY, HSQC, and HMBC) and mass spectral data. Also, we report the sensory evaluation of 1 against sucrose for the sweetness property of this molecule.

scholarly journals A New Diterpene Glycoside: 15α-Hydroxy-Rebaudioside M Isolated from Stevia rebaudiana

2015 ◽  
Vol 10 (7) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Indra Prakash ◽  
Gil Ma ◽  
Cynthia Bunders ◽  
Krishna P. Devkota ◽  
Romila D. Charan ◽  
...  
Keyword(s):  
Spectral Data ◽  
Structure Elucidation ◽  
Stevia Rebaudiana ◽  
Hydroxyl Group ◽  
Mass Spectral Data ◽  
Complete Structure ◽  
Mass Spectral ◽  
Steviol Glycoside ◽  
Stevia Rebaudiana Bertoni

In a continued search for novel diterpenoid glycosides, we recently isolated and characterized a Rebaudioside M derivative with a hydroxyl group at position 15 in the central diterpene core from an extract of Stevia rebaudiana Bertoni. Here we report the complete structure elucidation of 15α-hydroxy-Rebaudioside M (2) on the basis of NMR (1H, 13C, COSY, HSQC-DEPT, HMBC, 1D TOCSY, NOESY) and mass spectral data. Steviol glycoside with a hydroxyl group at C-15 in the central diterpene core has not been previously reported.

scholarly journals Microwave Assisted Synthesis and Characterization of Schiff Base of 2-Amino Benzimidazole

2018 ◽  
Vol 10 (4) ◽  
Author(s):  
Garima Shrivastava ◽  
Manjul Shrivastava
Keyword(s):  
Schiff Base ◽  
Spectral Data ◽  
Aromatic Aldehyde ◽  
Synthesis And Characterization ◽  
Microwave Assisted Synthesis ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Microwave Assisted

New Schiff base (2-[(1H-benzimidazol-2-ylimino) methyl]-4,6- diiodophenol) was synthesized by the condensation of aryl/hetero aromatic aldehyde (3,5diiodosalicylaldehyde) with 2- amino benzimidazole under conventional and microwave conditions and characterized through IR, HNMR and Mass spectral data and CHN analysis

Phenolic Analogs of Amino Carboxylic-Acid Ligands for Tc-99m. 1. Synthesis and Characterization of N,N'-Ethylenebis[2-(-O-Hydroxyphenyl)Glycines] (Ehpg)

1987 ◽  
Vol 40 (10) ◽  
pp. 1695 ◽  
Author(s):  
JG Wilson
Keyword(s):  
Carboxylic Acid ◽  
Spectral Data ◽  
Dimethyl Ester ◽  
Synthesis And Characterization ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Amino Carboxylic Acid

Nine N,N'- ethylenebis [2-(o- hydroxyphenyl ) glycines ] ( ehpg ) have been prepared and characterized by conversion into their dimethyl ester dihydrochlorides. Their i.r ., 1H n.m.r. and f.a.b. mass spectral data are presented and discussed.

scholarly journals Isolation and Structural Characterization of a New Minor Diterpene Glycoside from Stevia rebaudiana

2014 ◽  
Vol 9 (12) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Venkata Sai Prakash Chaturvedula ◽  
Julian Zamora
Keyword(s):  
High Resolution ◽  
Structural Characterization ◽  
Spectroscopic Data ◽  
Stevia Rebaudiana ◽  
2D Nmr ◽  
Stevia Rebaudiana Bertoni ◽  
High Resolution Mass ◽  
Commercial Extract ◽  
Resolution Mass

From the commercial extract of the leaves of the sweet plant Stevia rebaudiana Bertoni obtained from Sinochem Qingdao Co. Ltd., a new diterpene glycoside having three β-D-glucopyranosyl units of which two of them were connected in a relatively rare linkage of 3-β-D-glucobiosyl substitution at C-19 position of the aglycone steviol. The structure of the new compound has been characterized as 13-β-D-glucopyranosyloxy ent-kaur-16-en-19-oic acid-[(3-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester (1) on the basis of extensive 1D (1H and 13C) and 2D NMR (TOCSY, HMQC, and HMBC), and High Resolution mass spectroscopic data as well as hydrolysis studies.

scholarly journals Synthesis and Characterization of 4-substituted-3,4-dihydro-4-(2,4- dioxopentan-3-yl)-3-phenylbenzo[e][1,3] Oxazin-2-ones

2020 ◽  
pp. 34-38
Author(s):  
Laxminarayana Eppakayala ◽  
Ravi Kumar Bommera ◽  
Sailaja Gummadelli ◽  
Thirumala Chary Maringanti
Keyword(s):  
Spectral Data ◽  
Synthesis And Characterization ◽  
Mass Spectral Data ◽  
Mass Spectral

Some substituted benzoxazine derivatives have been synthesized in simple two steps. The structures of the synthesized compounds were confirmed by NMR and Mass spectral data.

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