scholarly journals A New Isoflavan From the Heartwood of Dalbergia cochinchinensis

2021 ◽  
Vol 16 (10) ◽  
pp. 1934578X2110496
Author(s):  
Yanxia Zhong ◽  
Jiao Chen ◽  
Xinliang Mo ◽  
Zhifang Xu ◽  
Shengxiang Qiu ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Bacillus Thuringiensis ◽  
2D Nmr ◽  
Shigella Dysenteriae ◽  
Two Dimensional ◽  
One Dimensional ◽  
Spectroscopic Analyses ◽  
Absolute Stereochemistry

A new isoflavan, named dalbergiacochan A (1), was isolated from the heartwood of Dalbergia cochinchinensis, along with two known isoflavans, namely mucronulatol (2) and 2′-O-methylsepiol (3). Their structures were elucidated based on extensive spectroscopic analyses, including one-dimensional (1D) and two-dimensional nuclear magnetic resonance (2D NMR), and mass spectroscopy (MS) data, and the absolute stereochemistry of compound 1 was determined as R-3′,6-dihydroxy-2′,4′,8-trimethoxyisoflavan from its circular dichroism spectrum. Compound 1 was inactive against Escherichia coli, Bacillus thuringiensis, and Shigella dysenteriae.

scholarly journals A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina

2020 ◽  
Vol 15 (3) ◽  
pp. 1934578X2090288
Author(s):  
Man H. Koo ◽  
Min J. Kim ◽  
Jae E. Seo ◽  
Ji H. Kim ◽  
Se J. Han ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Phenolic Compound ◽  
Fast Atom Bombardment ◽  
2D Nmr ◽  
Antimicrobial Activities ◽  
Inhibitory Effect ◽  
Two Dimensional ◽  
One Dimensional ◽  
The Antarctic

A new chlorinated phenolic compound, methyl-3-chloro-2-hydroxy-4-methoxy-6-pentylbenzoate (1) and 4 known compounds (2-5) were isolated from the Antarctic lichen, Pertusaria dactylina ( Pertusariaceae). The structure of the new compound was determined by means of One-dimensional and two dimensional nuclear magnetic resonance (1D and 2D NMR) and high-resolution fast atom bombardment mass spectrometry (HRFABMS) experiments. The antimicrobial activities of compounds 1 to 5 against Staphylococcus aureus and Candida albicans were evaluated. The results showed that compound 1 exhibited a weak inhibitory effect against C. albicans with an IC50 value of 67 ± 7 μg/mL.

scholarly journals Novel Pyran Derivative Ornamented with free Amino and Nitrile Functionalities: Synthesis and Spectroscopic Characterization

2019 ◽  
Vol 9 (1S3) ◽  
pp. 278-282
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Free Amino ◽  
Spectroscopic Characterization ◽  
Spectroscopic Methods ◽  
Two Dimensional ◽  
Spectral Techniques ◽  
One Dimensional ◽  
One Step ◽  
Pyran Derivative

A novel 4H-pyran derivative tethered with free amino and nitrile groups (1) was synthesized from commercially available meta-bromobenzaldehyde, malononitrile and 2-(methacryloyloxy)ethyl 3-oxobutanoate by adopting a one-step three components reaction strategy. The structure of the synthesized 1 has been established based on physical and spectroscopic methods such as infrared, one dimensional proton and carbon nuclear magnetic resonance as well as two-dimensional HSQC and HMBC spectral techniques.

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