Stenosi carotidea: Confronto tra angio-RM e angio-TC spirale

1997 ◽  
Vol 10 (2_suppl) ◽  
pp. 93-95 ◽  
Author(s):  
T. Scarabino ◽  
G.M. Giannatempo ◽  
A. Simeone ◽  
F. Florio ◽  
N. Magarelli ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Internal Carotid ◽  
Three Dimensional ◽  
Clinical Signs ◽  
Spiral Ct ◽  
Non Invasive ◽  
Spiral Ct Angiography ◽  
Preliminary Study ◽  
Sensitivity Specificity ◽  
Higher Sensitivity

A preliminary study comparing three dimensional time of flight (TOF 3D) Magnetic Resonance angiography (MRA) and spiral CT angiography (SCTA) in the detection and evaluation of internal carotid stenosis. Digital subtraction angiography (DSA) was the gold standard. Twenty patients with clinical signs of cerebrovascular insufficiency underwent MRA, SCTA and DSA within a three day period. Both internal carotid arteries were evaluated for absence or degree of stenosis. Sensitivity, specificity, diagnostic accuracy, concordance, overstimation and understimation were assessed. MRA showed a higher sensitivity, specificity, diagnostic accuracy and concordance compared to SCTA (92% versus 80%, 98,2% versus 96,4%, 96,3% versus 88%, respectively). MRA demonstrated a 5% overstimation rate whereas SCTA demonstrated a 7,5% understimation rate. These differences are not statistically significant. These results suggest that MRA is the more useful, non invasive modality for the detection and evaluation of the internal carotid artery with a greater than 70% stenoses.

Three-dimensional spiral CT angiography in the detection of cerebral aneurysm

1998 ◽  
Vol 39 (3) ◽  
pp. 233-238 ◽  
Author(s):  
M. Strayle-Batra ◽  
M. Skalej ◽  
A. K. Wakhloo ◽  
U. Ernemann ◽  
R. Klier ◽  
...  
Keyword(s):  
3D Reconstruction ◽  
Ct Angiography ◽  
Internal Carotid ◽  
Three Dimensional ◽  
Spatial Relationship ◽  
Spiral Ct ◽  
Posterior Communicating Artery ◽  
Close Spatial Relationship ◽  
Spiral Ct Angiography ◽  
Acute Subarachnoid Hemorrhage

Purpose: The value of CT angiography in the detection and evaluation of aneurysms was compared to digital subtraction angiography (DSA) Material and Methods: Seventeen patients with acute subarachnoid hemorrhage (SAH) or with known or suspected aneurysm were investigated by means of spiral CT angiography, which included 3D reconstruction. These findings were compared with those at DSA Results: In 16 patients, 20 aneurysms were found; the remaining patient had an ectatic vessel that simulated an aneurysm. Seventeen of the angiographically proved aneurysms were detected at CT angiography (sensitivity 85%). One further aneurysm was identified retrospectively as the result of greater experience in the method. All the aneurysms that escaped detection at CT were 3 mm in size. All the vessels of the circle of Willis, except for the posterior communicating artery, were properly evaluated at CT angiography. Difficulties were encountered in assessing the posterior communicating artery and the extradural segment of the internal carotid artery owing to their close spatial relationship to the bony structures of the skull base and the cavernous sinus Conclusion: CT angiography is a low-risk technique with a low level of invasiveness that is useful in following up known aneurysms. The 3D reconstruction yields further topographic information that helps in the planning of endovascular or surgical intervention. The facility for rotating the reconstructed vessels and displaying them from different angles is of particular value in cases difficult to assess at angiography

scholarly journals A Large Cohort Study of SARS-CoV-2 Detection in Saliva: A Non-Invasive Alternative Diagnostic Test for Patients with Bleeding Disorders

Viruses ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2361
Author(s):  
Josiane Iole França Lopes ◽  
Carlos Alexandre da Costa Silva ◽  
Rodrigo Guimarães Cunha ◽  
Alexandra Martins Soares ◽  
Maria Esther Duarte Lopes ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Hospitalized Patients ◽  
Bleeding Disorders ◽  
Hematological Diseases ◽  
Non Invasive ◽  
Qrt Pcr ◽  
Large Cohort Study ◽  
The Mean ◽  
Sensitivity Specificity ◽  
Higher Sensitivity

Diagnosis of SARS-CoV-2 infections is mostly based on the nasopharyngeal swabs (NPS). However, this collection is invasive and uncomfortable, especially for children and patients with coagulopathies, whose NPS collection often causes bleeding. Thus, the aim of this study was to evaluate the usefulness and accuracy of saliva for the diagnosis of COVID-19 in patients presenting bleeding disorders. Samples of NPS, oropharyngeal swabs (OPS), and saliva were collected simultaneously from 1159 hospitalized patients with hematological diseases and from 524 healthcare workers, both symptomatic and asymptomatic for SARS-CoV-2. All samples were evaluated for SARS-CoV-2 by qRT-PCR. SARS-CoV-2 was detected in NPS, OPS and saliva from 16.9%, 14.4% and 15.6% individuals, respectively. Tests in saliva showed sensitivity, specificity, and overall agreement of 73.3%, 96.9% and 92.7% (=0.74), respectively. Salivary tests had good accuracy (AUC = 0.7) for discriminating negative and positive qRT-PCR for SARS-CoV-2. Higher sensitivity was observed in symptomatic than in non-symptomatic patients, as well as in healthy subjects than in patients with hematological disease, in both OPS and saliva. The mean viral load in NPS was significantly higher than in OPS and in saliva samples (p < 0.001). Saliva is a good diagnostic tool to detect SARS-CoV-2, especially among patients symptomatic for COVID-19, and is a valuable specimen for mass screening of hospitalized patients with hematological diseases, especially for those that with bleeding disorders.

Three-dimensional spiral CT angiography of the abdomen: initial clinical experience.

Radiology ◽  
1993 ◽  
Vol 186 (1) ◽  
pp. 147-152 ◽  
Author(s):  
G D Rubin ◽  
M D Dake ◽  
S A Napel ◽  
C H McDonnell ◽  
R B Jeffrey
Keyword(s):  
Ct Angiography ◽  
Clinical Experience ◽  
Three Dimensional ◽  
Spiral Ct ◽  
Spiral Ct Angiography ◽  
Initial Clinical Experience

Three-dimensional spiral CT angiography in the detection of cerebral aneurysm

1998 ◽  
Vol 39 (3) ◽  
pp. 233-238 ◽  
Author(s):  
M. Strayle-Batra ◽  
M. Skalej ◽  
A. K. Wakhloo ◽  
U. Ernemann ◽  
R. Klier ◽  
...  
Keyword(s):  
Cerebral Aneurysm ◽  
Ct Angiography ◽  
Three Dimensional ◽  
Spiral Ct ◽  
Spiral Ct Angiography

Diagnostic Accuracy of Ultrasound in Palpable Breast Lesions

2020 ◽  
Vol 5 (3) ◽  
pp. 1196-1200
Author(s):  
Manish Raj Pathak ◽  
Mahesh Gautam ◽  
Rashmita Bhandari
Keyword(s):  
Positive Predictive Value ◽  
Diagnostic Accuracy ◽  
Negative Predictive Value ◽  
Diagnostic Tool ◽  
Predictive Value ◽  
Breast Lesions ◽  
Non Invasive ◽  
Malignant Lesions ◽  
Palpable Breast ◽  
Sensitivity Specificity

Introduction: Breast carcinoma is the second leading cause of cancer related mortality in females around the world. Ultrasound plays a key role in differentiating cystic and solid lesions and is a convenient and non-invasive diagnostic tool to differentiate between benign and malignant lesions. Objectives: The aim of this study is to evaluate the diagnostic accuracy of ultrasound in palpable breast lesions. Methodology: A prospective cross-sectional study was carried out in patients with palpable breast lesions who presented in Department of radio diagnosis and imaging of Nobel Medical collegefor a period of one-year from February 2019- January 2020 using ultrasound. A total of 60 patientswereevaluated in the study. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated. Results: Out of 60 patients evaluated, ultrasound showed 46 (76.7%) cases to be benign and 14 (23.3%) cases to be malignant. FNAC revealed benign disease in 47 (78.3%) patients and malignant disease in 13 (21.7%) patients. The most common benign lesion was fibroadenoma. We found nearly 91.7% of the malignant lesions had spiculated margins and microcalcification. The sensitivity of ultrasound was 95.74% and specificity 92.3% with diagnostic accuracy 95%. Conclusion: Ultrasound is a convenient and non-invasive diagnostic tool with good sensitivity, specificity, positive predictive value, negative predictive value and accuracy in palpable breast lesions.

Hepatic artery aneurysms: Evaluation using three-dimensional spiral CT angiography

1997 ◽  
Vol 52 (3) ◽  
pp. 227-230 ◽  
Author(s):  
S.J. Howling ◽  
H. Gordon ◽  
T. McArthur ◽  
A. Hatfield ◽  
W.R. Lees
Keyword(s):  
Hepatic Artery ◽  
Ct Angiography ◽  
Three Dimensional ◽  
Spiral Ct ◽  
Spiral Ct Angiography

The added value of SPECT/spiral CT in patients with equivocal bony metastasis from hepatocellular carcinoma

2015 ◽  
Vol 54 (06) ◽  
pp. 255-261 ◽  
Author(s):  
H. Shi ◽  
B. Li ◽  
L. Cai ◽  
Y. Gu ◽  
Y. Xiu ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Diagnostic Accuracy ◽  
Predictive Value ◽  
Spiral Ct ◽  
Whole Body ◽  
Bone Lesions ◽  
Kappa Value ◽  
Sensitivity Specificity

SummaryThe aim of this study was to evaluate the incremental value provided by single-photon emission computed tomography (SPECT)/spiral computed tomography (CT) over SPECT alone for the evaluation of equivocal bone lesions in patients with hepatocellular carcinoma (HCC). Patients, methods: This was a retrospective study of 65 patients (61 men and 4 women; mean age, 53.1 ± 10.1 years; age range, 31–78 years) with HCC confirmed by pathology who underwent planar whole body scintigraphy and SPECT/CT. Each lesion was scored visually using a 5-point scale (0, negative; 1, benign; 2, likely benign; 3, likely bone metastasis; 4, bone metastasis). Lesions in which diagnostic confidence was scored as 3 or 4 were categorized into metastases.The final diagnosis of each lesion was based on pathological confirmation or follow-up by whole body scintigraphy and SPECT/spiral CT conducted two or more times. The diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of SPECT alone and SPECT/CT were computed. Results: The diagnostic accuracy, sensitivity, specificity, PPV, and NPV of SPECT alone were 78.4, 70.9%, 94.9%, 96.8% and 59.7%, respectively. Moreover, for agreement of SPECT alone and the final results, the kappa value was 0.567 (p < 0.001), which was considered to be moderate agreement. The diagnostic accuracy, sensitivity, specificity, PPV, and NPV of SPECT/CT were 99.2%, 100%, 97.4%, 98.9% and 100 %, respectively. Furthermore, for agreement of SPECT/CT and the final results, the kappa value was 0.981 (p < 0.001), which was considered to be nearly perfect agreement. Conclusions: SPECT/spiral CT is more accurate and valuable than SPECT alone in the differential diagnosis of equivocal bone lesions in patients with HCC.

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