Use of a do-it-yourself artificial pancreas system is associated with better glucose management and higher quality of life among adults with type 1 diabetes

Background: Previous studies show that the use of do-it-yourself artificial pancreas system (DIYAPS) may be associated with better glycemic control characterized by improved estimated hemoglobin A1c (eHbA1c) and time in range among adults with type 1 diabetes (T1D). However, few studies have demonstrated the changes in laboratory-measured HbA1c, which is a more accepted index for glycemic control, after using a DIYAPS. Methods: This is a retrospective before-after study approaching patients who reported self-use of AndroidAPS. The main inclusion criteria included: T1D; aged ⩾18 years; having complete record of ⩾3 months of continuous AndroidAPS use; with laboratory-measured HbA1c and quality of life scale data before and after 3 months of AndroidAPS use; and not pregnant. The primary outcome was the change in HbA1c between baseline and 3 months after initiation of AndroidAPS use. Results: Overall, 15 patients (10 females) were included; the median age was 32.2 years (range: 19.2–69.4), median diabetes duration was 9.7 years (range: 1.8–23.7) and median baseline HbA1c was 7.3% (range: 6.4–10.1). The 3 months of AndroidAPS use was associated with substantial reductions in HbA1c [6.79% (SD: 1.29) versus 7.63% (SD: 1.06), p = 0.002] and glycemic variability when compared with sensor-augmented pump therapy. A lower level of fear of hypoglycemia [22.13 points (SD: 6.87) versus 26.27 points (SD: 5.82), p = 0.010] was also observed after using AndroidAPS. Conclusions: The 3 months of AndroidAPS use was associated with significant improvements in glucose management and quality of life among adults with T1D.

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Generic and disease-specific quality of life in adolescents with type 1 diabetes: comparison to age-matched healthy peers

Journal of Pediatric Endocrinology and Metabolism ◽

10.1515/jpem-2015-0397 ◽

2016 ◽

Vol 29 (7) ◽

Cited By ~ 4

Author(s):

Andrea Lukács ◽

Péter Sasvári ◽

András Török ◽

László Barkai

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Glycemic Control ◽

Diabetes Management ◽

Insulin Pump ◽

Insulin Pump Therapy ◽

Regular Exercise ◽

Pump Therapy

AbstractThis study aimed to evaluate the health-related quality of life (HRQoL) of adolescents with type 1 diabetes (T1DM) on the basis of the pediatric quality of life inventory™ (PedsQL™) generic and diabetes-specific modules, and to compare it to that of healthy peers.This retrospective case-control study involved 650 participants between ages of 13 and 19 years including 296 adolescents with T1DM from four diabetes centers and 354 healthy peers matched for age and gender from three different cities of the country. Participants completed the validated PedsQL™ for assessing the HRQoL. The analysis included an independent t-test to compare the means of the total and subscales of the PedsQL™ between boys and girls as well as between a healthy group and a group with T1DM. Gender differences in exercise, insulin therapy modalities were evaluated with the Pearson χAdolescents with T1DM have similar HRQoL in all domains when compared to their healthy counterparts. Females report worse HRQoL regardless of the presence of the disease. Insulin pump therapy facilitates better glycemic control and HRQoL. Regular exercise positively correlates with the generic HRQoL in both groups; however, it has no relationship with glycemic control.Optimal metabolic control and improved HRQoL are the eventual goals of diabetes management. Despite the difficulties, adolescents with diabetes can manage their disease well and live normal lives, similar to their healthy peers. Although diabetes-related problems exist, it seems that regular exercise and staying physically active, as well as promoting insulin pump therapy where it is applicable are related to favorable HRQoL.

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Insulin Management for Type 1 Diabetic Patients During Social Alcohol Consumption: The SPRITZ Study

Current Diabetes Reviews ◽

10.2174/1573399815666190507121332 ◽

2020 ◽

Vol 16 (6) ◽

pp. 619-627

Author(s):

Elisa Cipponeri ◽

Cesare Blini ◽

Christian Lamera ◽

Valentina De Mori ◽

Giovanni Veronesi ◽

...

Keyword(s):

Quality Of Life ◽

Glycemic Control ◽

Educational Program ◽

Insulin Pump ◽

Insulin Pump Therapy ◽

Pump Therapy ◽

Adult Type ◽

Time To Peak

Background : There is no data available on the best insulin treatment to counteract the effects of glucose excursions due to a moderate alcohol intake associated with portions of slight fat and protein-containing food, as often the case during social happenings or “happy hours”. Introduction: This study analyzes the glycemic control and quality of life in 8 adult type 1 diabetic (T1D) patients on insulin-pump therapy which were invited to consume a traditional Italian aperitif (“Spritz” and chips). Introduction : This study analyzes the glycemic control and quality of life in 8 adult type 1 diabetic (T1D) patients on insulin-pump therapy which were invited to consume a traditional Italian aperitif (“Spritz” and chips). Methods: Patients consumed Spritz aperitif twice: using their habitual bolus, based on carbohydrates (CHO) counting (V1), or with a personalized, advanced bolus (V2) calculated from insulin/Kcal derived from Fats and Proteins (FPU). Post-prandial glucose was continuously monitored; glucose incremental areas (iAUC), glucose peak and time to peak, and estimated change from V1 to V2 from repeated- measures models were computed. Each patient fulfilled validated questionnaires on quality of life, knowledge about diabetes and CHO counting. Results : After the educational program, a reduced iAUC (0-80 min: -306, p=ns; 40-80 min: -400, p=0.07) due to greater (p=0.03) and prolonged double-wave insulin boluses was observed. Blood glucose peak and time to peak were also reduced. Moreover, improvements in the psycho-affective dimension, as well as in the alimentary knowledge were detected. Conclusion: Therefore, a personalized educational program on CHO + FPU counting together with insulin bolus management can improve glycemic control during social consumption of alcohol, with positive reflections on the psycho-affective dimension. Further studies are mandatory to confirm such preliminary results.

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Linguistic and Psychometric Validation of the Diabetes-Specific Quality-of-Life Scale in U.K. English for Adults With Type 1 Diabetes

Diabetes Care ◽

10.2337/dc12-0076 ◽

2012 ◽

Vol 36 (5) ◽

pp. 1117-1125 ◽

Cited By ~ 21

Author(s):

D. Cooke ◽

M. C. O'Hara ◽

N. Beinart ◽

S. Heller ◽

R. La Marca ◽

...

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Psychometric Validation ◽

Quality Of Life Scale ◽

Life Scale

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The Association between a Low Carbohydrate Diet, Quality of Life and Glycemic Control in Australian Adults living with Type 1 Diabetes: A Pilot Study Protocol (Preprint)

JMIR Research Protocols ◽

10.2196/25085 ◽

2020 ◽

Author(s):

Janine Paul ◽

Rati Jani ◽

Peter Davoren ◽

Cathy Knight-Agarwal

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Pilot Study ◽

Glycemic Control ◽

Diet Quality ◽

Carbohydrate Diet ◽

Low Carbohydrate Diet ◽

Low Carbohydrate

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Adaptation of Diabetes-Specific Quality-of-Life Scale for patients with type 1 diabetes

Alad ◽

10.24875/alad.18000328 ◽

2018 ◽

Vol 8 (2) ◽

Author(s):

Natalia Soledad Sahi ◽

Marcos Cupani ◽

Franco Daniel Cortez ◽

Graciela Beatriz Rubin

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Quality Of Life Scale ◽

Life Scale

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Impact of Real-Time CGM Data Sharing on Quality of Life in the Caregivers of Adults and Children with Type 1 Diabetes

Journal of Diabetes Science and Technology ◽

10.1177/1932296820978423 ◽

2020 ◽

pp. 193229682097842

Author(s):

William H. Polonsky ◽

Addie L. Fortmann

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Glycemic Control ◽

Health Outcomes ◽

Real Time ◽

Data Sharing ◽

Diabetes Management ◽

Health Benefits

Background: To examine caregivers’ experiences with real-time continuous glucose monitoring (RT-CGM) data sharing and its impact on quality of life (QoL) and health outcomes. Methods: Parents of children with type 1 diabetes (T1D) ( N = 303) and spouses/partners of T1D adults ( N = 212) using the Dexcom G5 Mobile or G6 RT-CGM system and who were actively following their T1Ds’ RT-CGM data completed a survey examining their perceived value of data sharing, the impact of sharing on their own QoL and their child/partner’s health, and how they used RT-CGM data to support their T1Ds’ diabetes management. Regression analyses examined whether their actions were linked to reported changes in QoL and health outcomes. Results: Respondents were predominantly non-Hispanic White (91.1% parents; 88.7% partners), female (78.2% parents; 54.7% partners), and college-educated (65.3% parents; 61.8% partners). The majority reported that data sharing had enhanced hypoglycemic confidence (97.7% parents; 98.1% partners), overall well-being (60.4% parents; 63.2% partners), and sleep quality (78.0% parents; 61.3% partners). Of note, three positive caregiver actions were broadly consistent and significant predictors of QoL and health benefits for both parents and partners: celebrating success related to glycemic control, providing encouragement when glycemic control is challenging, and teamwork discussions about how the caregiver should respond to out-of-range values. Conclusions: RT-CGM data sharing was associated with a range of QoL and health benefits for caregivers. Degree of benefits was influenced by the collaborative actions taken by caregivers to support their child’s or partner’s diabetes management. To determine the most effective strategies for collaborative data sharing, longitudinal trials are needed.

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