scholarly journals The cocaine-e-cigarette – A theoretical concept of a harm reduction device for current users of smokable cocaine forms

2021 ◽  
Vol 7 ◽  
pp. 205032452110493
Author(s):  
Fabian P Steinmetz ◽  
Heino Stöver

Although there are great regional differences, smokable forms of cocaine (crack, free-base, paco, etc.) are a drug complex associated with often harmful and problematic drug use patterns. While strategies based on drug prohibition did not eradicate the consumption of smokable cocaine forms, prohibition itself led to many harmful effects, such as criminalisation, stigmatisation, unpredictable smokable cocaine forms quality and hardly any safer-use education. While there are many positive insights from heroin-assisted treatment programs with regard to heroin users, there are no comparable programs for problematic users of smokable cocaine forms. Smokable cocaine forms are challenging due to their different pharmacology and particularly their short duration leading to often many administrations per day. In this manuscript a device for a heroin-assisted treatment-like program for problematic users of smokable cocaine forms is suggested. This device is a cocaine-e-cigarette which could be prescribed to problematic users of smokable cocaine forms to reduce the risk of lung damage, exclude potentially harmful adulterants, limit intake (by formulation and/or technical settings) and also to bring users of smokable cocaine forms into the medical system to address comorbidities and risk factors, for example cardiovascular conditions, insomnia, depression, etc. This manuscript describes basic functionality and general specifications of a cocaine-e-cigarette as a medical device treating people with respective cocaine use disorder when cessation and substitution are not considered an option.

Author(s):  
Asma Al-Turkait ◽  
Lisa Szatkowski ◽  
Imti Choonara ◽  
Shalini Ojha

Rational prescribing is challenging in neonatology. Drug utilization studies help identify and define the problem. We performed a review of the literature on drug use in neonatal units and describe global variations. We searched databases (EMBASE, CINAHL and Medline) from inception to July 2020, screened studies and extracted relevant data (two reviewers). The search revealed 573 studies of which 84 were included. India (n = 14) and the USA (n = 13) reported the most. Data collection was prospective (n = 56) and retrospective (n = 26), mostly (n = 52) from one center only. Sixty studies described general drug use in 34 to 450,386 infants (median (IQR) 190 (91–767)) over a median (IQR) of 6 (3–18) months. Of the participants, 20–87% were preterm. The mean number of drugs per infant (range 11.1 to 1.7, pooled mean (SD) 4 (2.4)) was high with some reporting very high burden (≥30 drugs per infant in 8 studies). This was not associated with the proportion of preterm infants included. Antibiotics were the most frequently used drug. Drug use patterns were generally uniform with some variation in antibiotic use and more use of phenobarbitone in Asia. This study provides a global perspective on drug utilization in neonates and highlights the need for better quality information to assess rational prescribing.


1976 ◽  
Vol 5 (2) ◽  
pp. 17-23
Author(s):  
Samuel E. Krug ◽  
Thomas J. Henry

1979 ◽  
Vol 9 (1) ◽  
pp. 67-78 ◽  
Author(s):  
Carol J. Turner ◽  
Robert J. Willis

As part of an extensive questionnaire on student drug use patterns at a small private college, this study was completed to determine the relationship between self-reported religiosity of college students and 1) the nature and incidence of current drug usage, 2) reasons for abstaining from drug use, 3) acceptable sources for referral in case of drug problems, and 4) persons with whom students would discuss their attitudes toward drugs. Statistically significant differences between religious and non-religious students at the 0.01 level were found in the current use of alcohol and marijuana, in reasons for abstaining from marijuana, amphetamines, barbiturates, and hallucinogens; in referral of drug problems to drug wise friends; and in discussing drug attitudes with parents and with college counselors.


2017 ◽  
Vol 61 (5) ◽  
pp. 612-618 ◽  
Author(s):  
Scott E. Hadland ◽  
Evan Wood ◽  
Ekaterina Nosova ◽  
Thomas Kerr ◽  
Kora DeBeck

2015 ◽  
Vol 156 ◽  
pp. e162 ◽  
Author(s):  
Nalini Negi ◽  
Avelardo Valdez ◽  
Alice Cepeda

Sign in / Sign up

Export Citation Format

Share Document