scholarly journals Massive haemorrhage: an unusual presentation of systemic lupus erythematosus

JRSM Open ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 205427042110620
Author(s):  
Wajeeha Qayyum ◽  
Sohail Khan ◽  
Muhammad Shahid Iqbal ◽  
Muhammad Fozan Khan ◽  
Zaland Ahmed Yousafzai ◽  
...  

Summary Systemic lupus erythematosus (SLE) usually affects young females and its presentation with haemorrhage is unusual. Intracerebral bleed (ICB) has been described in a few case reports, but massive haematuria has not been reported in the literature so far. Here, we present a case of a 56 year-old-lady who presented with expanding lobar bleed and massive haematuria as the first presentation of SLE secondary to vasculitis. Lupus vasculitis usually presents with thrombosis-related complications and although bleeding in this context is rare, it can lead to catastrophic consequences. Hence, vasculitis-related bleeding should be taken under consideration in a challenging situation like ours.

Lupus ◽  
2011 ◽  
Vol 20 (11) ◽  
pp. 1214-1218 ◽  
Author(s):  
M Frigui ◽  
F Frikha ◽  
D Sellemi ◽  
F Chouayakh ◽  
J Feki ◽  
...  

Lupus ◽  
2018 ◽  
Vol 28 (1) ◽  
pp. 133-136 ◽  
Author(s):  
H. Furuya ◽  
K. Ikeda ◽  
K. Iida ◽  
K. Suzuki ◽  
S. Furuta ◽  
...  

Toxoplasma is a common parasite worldwide that mainly affects the brain, lungs and eyes. Although toxoplasmic encephalitis is a lethal disease without treatment, past case reports show most patients with systemic lupus erythematosus who developed toxoplasmic encephalitis were misdiagnosed and treated as neuropsychiatric systemic lupus erythematosus, which led to unfavorable outcomes. We herein describe a case of disseminated toxoplasmosis affecting all the above organs with atypical symptoms, which developed with exacerbation of systemic lupus erythematosus. She had initially manifested with retinochoroiditis without vitritis, mild cognitive impairment and an isolated lung mass. These are completely different from the classic symptoms of toxoplasmosis that have been reported in patients with HIV infection and/or those after hematopoietic transplantation. Our case, together with previously reported cases, suggests the manifestation of toxoplasmosis that develops in systemic lupus erythematosus patients can be different from that seen in conventional cases and varies between individual patients. Our case highlights both the difficulty in and the importance of diagnosing toxoplasmosis in patients with systemic lupus erythematosus and provides helpful information to identify this rare, devastating, yet treatable disease.


2004 ◽  
Vol 19 (1) ◽  
pp. 134 ◽  
Author(s):  
Mi-Jeong Park ◽  
Yun-A Kim ◽  
Shin-Seok Lee ◽  
Byeong-Chae Kim ◽  
Myeong-Kyu Kim ◽  
...  

2018 ◽  
Vol 131 (5) ◽  
pp. e189-e190 ◽  
Author(s):  
Persio D. López ◽  
Rachna Valvani ◽  
Savi Mushiyev ◽  
Ferdinand Visco ◽  
Gerald Pekler

2022 ◽  
Vol 71 (12) ◽  
Author(s):  
Pooja Deepak ◽  
Roha Saeed Memon ◽  
Fizza Tariq ◽  
Hassan Ahmed ◽  
Shaheen Bhatti

Systemic lupus erythematosus (SLE) is an autoimmune disease that has certain characteristic features but can also present with misleading signs and symptoms especially when it is of late-onset. Various case reports address its association with thrombotic thrombocytopenic purpura (TTP), however, its association with parkinsonism remains unclear. We present the case of a 58-year-old male who reported with acute-onset parkinsonism along with some gastrointestinal symptoms. Detailed laboratory investigations unmasked the underlying SLE with an overlapping picture of TTP. This unusual presentation in a resource-constrained setting created challenges and subsequent delays in the diagnosis and management of the patient. Despite urgent care, the patient’s age, presence of overlapping conditions, and multi-organ involvement were some of the factors due to which the treatment failed and he could not survive. We report the association of SLE with secondary TTP and parkinsonism.


Medicine ◽  
2018 ◽  
Vol 97 (34) ◽  
pp. e11933 ◽  
Author(s):  
Delphine Lebrun ◽  
Ailsa Robbins ◽  
Maxime Hentzien ◽  
Ségolène Toquet ◽  
Julie Plee ◽  
...  

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