scholarly journals What causes fibromyalgia? An online survey of patient perspectives

2018 ◽  
Vol 5 (2) ◽  
pp. 205510291880268 ◽  
Author(s):  
Penny J Furness ◽  
Katharina Vogt ◽  
Simon Ashe ◽  
Sophie Taylor ◽  
Sarah Haywood-Small ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Quantitative Research ◽  
Online Survey ◽  
Illness Narratives ◽  
Emotional Trauma ◽  
Chronic Pain Condition ◽  
Pain Condition ◽  
Client Relationships ◽  
Patient Expertise ◽  
Severe Chronic Pain

Fibromyalgia is a severe chronic pain condition that affects every aspect of life. Causes of the condition remain unclear, and quantitative research cannot account for patients’ personal illness narratives and perceptions. This online survey gathered qualitative accounts of the perceived causes of their condition from 596 people with fibromyalgia, which were analyzed thematically. Themes were “Bodily assault, ill-health, and change”; “Emotional trauma and distress”; “Stress and vulnerability”; and “Explaining and authenticating fibromyalgia.” Discussion focuses on the complexity of causation, the importance of understanding and having symptoms validated, and the potential for benefiting from patient expertise in building better practitioner–client relationships.

5-HT3 receptor within the amygdaloid complex modulates pain hypersensitivity induced by empathy model of cohabitation with a partner in chronic pain condition in mice

2021 ◽  
Author(s):  
Lígia Renata Rodrigues Tavares ◽  
Vinícius Pelarin ◽  
Daniela Baptista-de-Souza ◽  
Daniele Pereira Ferrari ◽  
Ricardo Luiz Nunes-de-Souza ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Amygdaloid Complex ◽  
Chronic Pain Condition ◽  
Pain Hypersensitivity ◽  
Pain Condition

scholarly journals MicroRNA expression profiles differentiate chronic pain condition subtypes

2015 ◽  
Vol 166 (6) ◽  
pp. 706-720.e11 ◽  
Author(s):  
Brittney P. Ciszek ◽  
Asma A. Khan ◽  
Hong Dang ◽  
Gary D. Slade ◽  
Shad Smith ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Expression Profiles ◽  
Microrna Expression ◽  
Chronic Pain Condition ◽  
Pain Condition

Temporomandibular Disorders in Traumatic Brain Injury Patients: A Chronic Pain Condition Requiring Further Attention

Pain Medicine ◽  
2020 ◽  
Vol 21 (12) ◽  
pp. 3260-3262
Author(s):  
Alberto Herrero Babiloni ◽  
Fernando G Exposto ◽  
Yasmine Bouferguene ◽  
Yuri Costa ◽  
Gilles J Lavigne ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Chronic Pain ◽  
Brain Injury ◽  
Temporomandibular Disorders ◽  
Chronic Pain Condition ◽  
Pain Condition

Fibromyalgia: A “Chronic Pain Condition” or a True “Chronic Pain Disease”?

Pain Practice ◽  
2017 ◽  
Vol 18 (2) ◽  
pp. 283-283
Author(s):  
Cesare Bonezzi ◽  
Matteo L.G. Leoni ◽  
Gaetano Terranova
Keyword(s):  
Chronic Pain ◽  
Chronic Pain Condition ◽  
Pain Condition

Pain revised – learning from anomalies

2019 ◽  
Vol 20 (1) ◽  
pp. 29-32
Author(s):  
Lars-Petter Granan
Keyword(s):  
Chronic Pain ◽  
Clinical Medicine ◽  
Pain Treatment ◽  
Network Activity ◽  
Real World Data ◽  
Chronic Pain Condition ◽  
Pain Condition ◽  
Introductory Article ◽  
Starting Point ◽  
Chronic Pain Treatment

AbstractAs professional health care personnel we are well educated in anatomy, physiology, clinical medicine and so forth. Our patients present with various symptoms and signs that we use this knowledge to diagnose and treat. But sometimes the patient case contradicts our knowledge. Since the patient is the terrain and our knowledge is the map, these patient cases are anomalies that give us the opportunity to update our maps. One such anomaly is how time restricted amnesia can improve or even eradicate an underlying chronic pain condition and eliminate the patient’s dependence on daily opioid consumption. In this short communication I will use amnesia as a starting point to briefly review chronic pain from a learning and memory perspective. I will introduce, for many readers, new concepts like degeneracy and criticality, and together with more familiar concepts like habits and brain network activity, we will end with overarching principles for how chronic pain treatment in general can be crafted and individualized almost independently of the chronic pain condition at hand. This introductory article is followed by a review series that elaborates on the fundamental biological principles for chronic pain, treatment options, and testing the theory with real world data.

scholarly journals Successful and unsuccessful recruitment and retainment strategies in a UK multicentre drug trial for a rare chronic pain condition which performed above target

2019 ◽  
Vol 14 (3) ◽  
pp. 171-179
Author(s):  
Jatinder Bisla ◽  
Gareth Ambler ◽  
Bernhard Frank ◽  
Sumit Gulati ◽  
Poppy Hocken ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Clinical Trials ◽  
Pain Syndrome ◽  
Chronic Pain Patient ◽  
Recruitment Rate ◽  
Pain Patient ◽  
Trial Management ◽  
Old Patients ◽  
Chronic Pain Condition ◽  
Pain Condition

Introduction: Recruitment into trials in rare chronic pain conditions can be challenging, so such trials consequently are underpowered or fail. Methods: Drawing from our experience in conducting, to date, the largest academic trial in a rare chronic pain condition, complex regional pain syndrome, we have identified recruitment and retention strategies for successful trial conduct. Results: We present 13 strategies grouped across the categories of ‘setting the recruitment rate’, ‘networking’, ‘patient information’, ‘trial management’ and ‘patient retention’. Moreover, six recruitment risks are also discussed. A conservative recruitment estimate, based on audits of newly referred patients to the trial centres without taking into account availability of ‘old’ patients or recruitment from outside centres, and assuming a 55% patient refusal rate yielded accurate numbers. Conclusion: Appreciation of these identified recruitment challenges and opportunities may contribute to supporting prospective investigators when they design clinical trials for chronic pain patient population groups where it has been historically difficult to conduct high-quality and robust clinical trials.

Long-term outcome of multidisciplinary intervention of chronic non-cancer pain patients in a private setting

2012 ◽  
Vol 3 (2) ◽  
pp. 99-105 ◽  
Author(s):  
Villy Meineche-Schmidt ◽  
Niels-Henrik Jensen ◽  
Per Sjøgren
Keyword(s):  
Chronic Pain ◽  
Group Therapy ◽  
Pain Clinic ◽  
Secondary Outcome ◽  
Individual Treatment ◽  
Chronic Pain Condition ◽  
Pain Condition ◽  
Transfer Income

AbstractBackground and aimThe present study reports on chronic non-cancer patients who were referred to a private pain clinic, according to a waiting time guarantee and treated within one month from referral. Based on evaluation by members of the multidisciplinary staff at our pain clinic a pain management program could be offered individually or as group therapy.MethodsHealth related quality of life, psychometric tests, use of pain medication; socio-economic status and number of consultations in general practice were recorded at referral to the clinic and by postal questionnaires at follow-up 21 months later. The primary treatment outcome (treatment success) was defined as an improvement of at least 40 points in the physical component and/or the mental component of SF-36 from baseline to follow-up. Secondary outcome measures were changes in Beck’s Anxiety Inventory and Beck’s Depression Inventory, use of analgesics, work status and transfer income and number of consultations at the GP’s office due to the chronic pain condition.ResultsA total of 306 patients were included: 141 were treated individually and 165 were treated in groups. At follow-up, data were obtained from 189 patients (62%). Comparing baseline to follow-up data, 62% of group treated patients were treated successfully, compared with 41% of individually treated patients. Anxiety and depression were significantly improved in group treated patients but not in those treated individually. significantly more patients had work income (and less patients transfer income) among group treated, compared with individually treated. At follow-up use of antidepressants and anticonvulsants was increased whereas use of tranquilizers and strong opioids was decreased in all patients. Number of consultations at their GPs due to chronic pain was significantly reduced in all patients.ConclusionsMultidisciplinary treatment in a private pain clinic seems to have a long-term effect in relation to biological, psychological and social aspects of the chronic pain condition. Treatments based on group therapy may offer better results than individual treatment courses.ImplicationsThe effect of group therapy should be explored further.

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