Determinants of Seasonal Influenza Vaccine Uptake Among the Elderly in the United States: A Systematic Review and Meta-Analysis

Background: Despite the availability of a universal influenza vaccination program in the United States and Canada, seasonal influenza vaccine (SIV) uptake among the elderly remains suboptimal. Understanding the factors that determine SIV uptake in this important population subgroup is essential for designing effective interventions to improve seasonal influenza vaccination among the elderly. We evaluated the determinants of SIV uptake in the elderly in the United States and Canada. Methods: We systematically searched relevant bibliographic databases and websites from 2000 to 2017 for population-based clinical trials or observational studies conducted in community-based elderly individuals in the United States or Canada, irrespective of health status. Two reviewers independently screened the identified citations for eligibility using a two-stage sifting approach to review the title/abstract and full-text article. We gathered data on determinants of uptake (any vaccine receipt) and adherence (receipt of vaccine in more than one season) to seasonal influenza vaccination. Where possible, we pooled the data using inverse variance methods to minimize the variance of the weighted average. Results: Five cross-sectional studies on SIV uptake (none on adherence) from the United States met our eligibility criteria. Being older (pooled odds ratio [POR] = 1.44, 95% Confidence Interval [CI] = 1.11, 1.86); White (POR = 1.33, 95% CI = [1.10, 1.64]); and having higher income (POR = 1.06, 95% CI = [1.04, 1.09]); and health insurance (POR = 1.40, 95% CI = [1.25, 1.55]) were associated with increased SIV uptake. Conclusion: Older, ethnically White, higher income elderly individuals with access to health insurance coverage and a regular health care provider have higher SIV uptake in the United States. There was limited evidence for other socioeconomic and health-related determinants. Further studies are needed to provide an evidence base for planning more effective influenza vaccination programs in the United States.

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1650. Knowledge and Attitudes Toward Influenza Vaccination Among Hispanics: A Survey Conducted in Latin American Consulates in South Florida

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.1514 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S603-S603

Author(s):

Maria L Soler Hidalgo ◽

John M Abbamonte ◽

Laura Regalini ◽

Mariana Schlesinger ◽

Maria L Alcaide ◽

...

Keyword(s):

United States ◽

Health Insurance ◽

Influenza Vaccine ◽

Influenza Vaccination ◽

Latin American ◽

Multinomial Logistic Regression ◽

The United States ◽

South Florida ◽

Knowledge And Attitudes ◽

Hispanic Community

Abstract Background Each year Influenza causes between 12,000 and 56,000 deaths, and over half a million of hospitalizations in the United States. Despite the widespread availability of vaccination, immunization coverage is low. Less than half of American adults receive the influenza vaccine, and there is a disparity between Hispanic and non-Hispanics, with only 35.9% of Hispanic compared with 45.9% of white non-Hispanics receiving the vaccine. In Miami, South Florida, over two-thirds of the population is Hispanic, and rates of influenza vaccination are low. This study aims to identify the knowledge and attitudes toward influenza vaccination among members of the adult Hispanic community in Miami, and to identify barriers to vaccination in this population. Methods This is a cross-sectional study conducted during the influenza season in 2017 and 2019 (October to December). A survey was administered in the waiting rooms of participating Latin American Consulates (Argentina, Colombia, Ecuador, Guatemala, Honduras, Mexico, Peru, and Uruguay) in Miami. Participants included were older than 18 years, Hispanic, and with residence in the United States for more than 6 months. The participants accepted the inform consent orally. The survey was voluntary and anonymous. Results We enrolled 970 adults. The median age was 43 years, 50% were male, 60% had health insurance, and 67% had completed education of high school or higher. Knowledge regarding influenza and vaccination was low (78% believed asymptomatic individuals could transmit influenza, 14% knew that vaccination is recommended during the winter months, 50% felt not everyone should be vaccinated, 25% believed the vaccine causes influenza, and 7% autism). About one quarter (27%) received the influenza vaccine annually, 35% sometimes, and 38% never. Using multinomial logistic regression, we identified age χ2(2) = 19.38, P < 0.001, consulate χ2(6) = 160.21, P < 0.001, and insurance status χ2(2) = 23.04, P < 0.001 as predictors of receiving vaccination. Neither gender, nor education level found to be associated with vaccination behavior. Conclusion Immunization rates in the adult Hispanic population are low. Interventions to improve vaccination among Hispanics who are older and lack of health insurance are urgently needed in the diverse Hispanic community. Disclosures All authors: No reported disclosures.

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Effect of expanded US recommendations for seasonal influenza vaccination: comparison of two pediatric emergency departments in the United States and Canada

Canadian Medical Association Journal ◽

10.1503/cmaj.110241 ◽

2011 ◽

Vol 183 (13) ◽

pp. E1025-E1032 ◽

Cited By ~ 5

Author(s):

A. G. Hoen ◽

D. L. Buckeridge ◽

K. M. L. Charland ◽

K. D. Mandl ◽

C. Quach ◽

...

Keyword(s):

United States ◽

Influenza Vaccination ◽

Emergency Departments ◽

Seasonal Influenza ◽

The United States ◽

Pediatric Emergency ◽

Seasonal Influenza Vaccination

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Seasonal influenza vaccination trends from 2007–2011 in privately insured children and adults in the United States

Vaccine ◽

10.1016/j.vaccine.2014.07.009 ◽

2014 ◽

Vol 32 (48) ◽

pp. 6563-6568 ◽

Cited By ~ 7

Author(s):

Evgeniya Antonova ◽

Christopher S. Ambrose ◽

David Kern ◽

Stan L. Block ◽

Herve Caspard ◽

...

Keyword(s):

United States ◽

Influenza Vaccination ◽

Seasonal Influenza ◽

The United States ◽

Seasonal Influenza Vaccination ◽

Privately Insured

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Vaccination in pregnancy against pertussis and seasonal influenza: key learnings and components from high-performing vaccine programmes in three countries: the United Kingdom, the United States and Spain

BMC Public Health ◽

10.1186/s12889-021-12198-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Théophile Baïssas ◽

Florence Boisnard ◽

Inmaculada Cuesta Esteve ◽

Marta Garcia Sánchez ◽

Christine E. Jones ◽

...

Keyword(s):

United States ◽

United Kingdom ◽

Influenza Vaccination ◽

Pregnant Women ◽

Seasonal Influenza ◽

The United States ◽

Seasonal Influenza Vaccination ◽

High Performing ◽

The United Kingdom ◽

In Pregnancy

Abstract Background Pertussis and seasonal influenza are responsible for significant maternal, neonatal, and infant morbidity and mortality, but vaccine coverage rates (VCR) for both pertussis (administered as a tetanus, diphtheria, acellular pertussis [Tdap] vaccination) and seasonal influenza in pregnancy remain generally low. Only a small number of countries, including Spain, the United Kingdom (UK), and the United States (US), have high Tdap and seasonal influenza VCRs in pregnancy. The purpose of this study was to identify the key factors that contributed to the high VCRs observed in these countries. Methods The experience from both Tdap and seasonal influenza vaccination programmes during pregnancy were documented in Spain, the UK, and the US using a three-step approach. A literature review yielded 157 publications, and a further 117 documents were selected through desk research. A published five-pillar VCR framework for influenza was amended to evaluate the specific contributing factors leading to high Tdap and seasonal influenza VCRs among pregnant women. Results The analysis identified components that contributed to higher VCR in pregnant women across three different healthcare systems in Spain, UK, and US. The combination of several key interventions in each country led to a rapid increase in VCR that reached near-optimal levels (i.e. 75% for seasonal influenza) within a few years. As well as inclusion in national immunisation programme and vaccine reimbursement, key components that were identified included the mobilisation of health authorities, prenatal care Healthcare Professionals (HCP) and scientific societies, the inclusion of vaccination in antenatal medical guidance, the provision of educational material to HCPs, and a strong disease awareness driven by recent pertussis outbreaks in each country. Conclusions Although there is no simple, universal solution to improving sub-optimal VCRs, the list of components identified in this study from three countries with high-performing Tdap and seasonal influenza vaccination programmes provides a basis for public health and medical stakeholders in other countries to define strategies to successfully implement national vaccination programmes for pregnant women.

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Faculty Opinions recommendation of Effect of expanded US recommendations for seasonal influenza vaccination: comparison of two pediatric emergency departments in the United States and Canada.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13352978.14724083 ◽

2011 ◽

Author(s):

George Petrikkos ◽

Sotirios Tsiodras

Keyword(s):

United States ◽

Influenza Vaccination ◽

Emergency Departments ◽

Seasonal Influenza ◽

The United States ◽

Pediatric Emergency ◽

Seasonal Influenza Vaccination

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Public Knowledge, Attitudes, and Practices toward Seasonal Influenza Vaccine in Saudi Arabia: A Cross-Sectional Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18020479 ◽

2021 ◽

Vol 18 (2) ◽

pp. 479

Author(s):

Ibrahim A. Sales ◽

Wajid Syed ◽

Majed F. Almutairi ◽

Yazed Al Ruthia

Keyword(s):

Saudi Arabia ◽

Influenza Vaccine ◽

Influenza Vaccination ◽

Seasonal Influenza ◽

Seasonal Influenza Vaccine ◽

Seasonal Influenza Vaccination ◽

Attitudes And Practices ◽

Awareness Campaigns ◽

The Impact ◽

Knowledge Attitudes And Practices

Objectives: Increasing national influenza vaccination rates continues to be a challenge for Saudi Arabia. Therefore, the purpose of this study was to explore the Saudi public perceptions toward seasonal influenza vaccination and their association with the rate of vaccination. Methods: Individuals aged 15 years and older were surveyed about their knowledge, attitudes, and practices toward the seasonal influenza vaccine using a previously developed and validated 19-item online questionnaire. The impact of the participants’ perceptions toward the seasonal influenza vaccine on their past influenza vaccination history was assessed using multiple linear regressions. Results: The rate of regular vaccination among the 790 surveyed participants was 12.65%, and those who were aged <24 years had the highest rate (57%). The vast majority of the participants with chronic diseases (>90%) reported irregular vaccination histories against seasonal influenza. Participants who believed that the influenza vaccine is safe (β = 3.27; 95% CI: 2.067 to 5.171; p <0.001), efficacious (β = 2.87; 95% CI: 1.834 to 4.498; p <0.001), should be given during a specific time in the year (β = 1.821; 95% CI: 1.188 to 2.789; p = 0.0059), and were aware of their need to get vaccinated against the seasonal influenza (β = 2.781; 95% CI: 1.254 to 6.188; p = 0.0119) were more likely to have received the vaccine. Conclusion: The findings of this study suggest that the rate of seasonal influenza vaccination is low among the Saudi population, which necessitates the launching of public awareness campaigns about the importance of the seasonal influenza vaccine.

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Barriers Associated with Seasonal Influenza Vaccination among College Students

Influenza Research and Treatment ◽

10.1155/2016/4248071 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 10

Author(s):

Stephanie M. Benjamin ◽

Kaitlin O. Bahr

Keyword(s):

College Students ◽

Influenza Vaccine ◽

Influenza Vaccination ◽

Undergraduate Students ◽

Seasonal Influenza ◽

Public Health Education ◽

College Campuses ◽

Convenience Sample ◽

Seasonal Influenza Vaccine ◽

Seasonal Influenza Vaccination

Influenza can spread rapidly on college campuses because of high-density living conditions and frequent social interactions. However, seasonal influenza vaccination rates on college campuses are low. The purpose of this study is to identify barriers associated with receipt of the seasonal influenza vaccination. Questionnaires were completed by a convenience sample of 383 undergraduate students in January 2014. Data were analyzed to identify barriers associated with receiving the seasonal influenza vaccine. Only 20.6% of students reported receiving the vaccine within the last 6 months. Among students who did not receive the vaccine, 47.8% believed they would get influenza from the vaccine, 41.6% believed the vaccination may have dangerous side effects, and 39.6% believed they were not at risk for contracting influenza. The majority of nonvaccinated students did not believe cost of the vaccine or access to the vaccine were barriers. Many college students are not receiving the seasonal influenza vaccine, representing an important area for improvement. Understanding potential barriers associated with receipt of this vaccine is important for identifying and creating effective public health education programs and campaigns. There is a need for enhanced vaccination education efforts among college students, particularly with respect to the safety and importance of this vaccine.

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