Extranodal Non-Hodgkin Lymphoma: A Rare Presentation Involving the Pancreas

2021 ◽  
pp. 875647932110548
Author(s):  
Savannah Cerwin, BS RDMS
Keyword(s):  
Immune System ◽  
Gastrointestinal Tract ◽  
Hodgkin Lymphoma ◽  
Primary Site ◽  
Common Site ◽  
Rare Presentation ◽  
Splenic Hilum ◽  
Non Hodgkin Lymphoma ◽  
Uncommon Presentation

Non-Hodgkin lymphoma (NHL) is a cancer of the immune system, and accounts for 90% of all lymphomas. When lymphoma is discovered outside of the immune system, it is considered extranodal lymphoma. Any organ can be the primary site of NHL, with the gastrointestinal tract being the most common site of involvement. This case study explores the sonographic discovery of an uncommon presentation of NHL with an extranodal mass originating from the pancreatic body and tail, and further extending into the splenic hilum.

PERILOUS HIV BRINGS OUT DEADLY CANCERS

2020 ◽  
pp. 1-5
Author(s):  
Camila A Carlman ◽  
Bharat Mishra ◽  
Anita Patel
Keyword(s):  
Immune System ◽  
Hodgkin Lymphoma ◽  
Cancer Progression ◽  
Kaposi's Sarcoma ◽  
Cellular Proliferation ◽  
Kaposi’S Sarcoma ◽  
Hiv Patients ◽  
Non Hodgkin Lymphoma ◽  
Increased Risk ◽  
Risk Of Cancer

Human Immunodeficiency Virus (HIV) infection is both infectious and contagious disease. The people infected with HIV have an increased risk of cancer while comparing with uninfected people. Kaposi’s sarcoma, aggressive B-cell Non-Hodgkin Lymphoma & cervical cancer are the three types of cancers which are termed as “HIV –associated cancers”. Apart from these cancers, HIV patients are prone to cancers of anus, liver, lung, pharynx which are termed as “non-AIDS defining cancers”. Viral oncogenesis and cytokine induced growth contribute to the development of Kaposi sarcoma. Several virally encoded genes such as bcl-2, IL-6, cyclin-D, GPCR & interferon regulatory factor, plays key role in cellular proliferation and survival.  Infection with HIV weakens the immune system and reduces the body’s ability to fight against viral infections that may lead to cancer. Immunosuppression and inflammation in HIV patients also contribute to cancer progression. The complications of AIDS- related cancers include easy bleeding and bruising, tiredness, nausea, vomiting, poor appetite, mouth sores, hair loss etc. According to the data, HIV infected males are more susceptible to Kaposi’s sarcoma and Non- Hodgkin Lymphoma whereas females are more liable to cervical cancers. Early diagnosis and treatment options help to drop the risk of AIDS related cancers. The HAART therapy reduces the risk of cancer in HIV patients by lowering the amount of HIV circulating in blood, so that function of immune system to fight against the virus can be restored. Other treatment methods are chemotherapy, immunotherapy, radiation and surgery.

Non-Hodgkin Lymphoma (NHL) linkage with residence near heavy roads—A case study from Haifa Bay, Israel

2009 ◽  
Vol 15 (2) ◽  
pp. 636-641 ◽  
Author(s):  
Shlomit Paz ◽  
Shai Linn ◽  
Boris A. Portnov ◽  
Amir Lazimi ◽  
Boris Futerman ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Non Hodgkin Lymphoma

scholarly journals Gastrointestinal Tract Lymphomas: A Review of the Most Commonly Encountered Lymphomas

2021 ◽  
Author(s):  
Jessica Alvarez-Lesmes ◽  
Jennifer R. Chapman ◽  
Daniel Cassidy ◽  
Yi Zhou ◽  
Monica Garcia-Buitrago ◽  
...  
Keyword(s):  
B Cell ◽  
Hodgkin Lymphoma ◽  
Cell Lineage ◽  
B Cell Lymphoma ◽  
Gi Tract ◽  
Common Site ◽  
Anatomic Site ◽  
Non Hodgkin Lymphoma ◽  
Pubmed Database ◽  
Data Source

Context.— The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin lymphoma, accounting for 20% to 40% of all extranodal lymphomas. The majority of these are systemic processes secondarily involving the GI tract. Primary GI lymphomas are less common, accounting for approximately 10% to 15% of all non-Hodgkin lymphoma. Most non-Hodgkin lymphoma involving the GI tract are of B-cell lineage, of which diffuse large B-cell lymphoma is the most common subtype, irrespective of location. Objective.— To review the lymphoproliferative neoplasms of B-cell and T-cell lineage involving the luminal GI tract according to the most prevalent subtypes at each anatomic site. Data Source.— Systematic search of the PubMed database for updated literature on GI lymphomas epidemiology, subtypes, clinical, endoscopic, and genetic findings. Histologic images are derived from our collection of clinical cases. Conclusions.— The GI tract is the most common site of extranodal lymphoproliferative neoplasms. Recognition of the most frequently encountered GI lymphomas is imperative for patient management and treatment.

scholarly journals Large Bleeding Tonsillar Mass in a Child - Rare Presentation of Non-Hodgkin Lymphoma

2020 ◽  
Vol 40 (3) ◽  
pp. 270-273
Author(s):  
Ramesh Bhat Y ◽  
Anand Kumar Patil
Keyword(s):  
Hodgkin Lymphoma ◽  
Rare Presentation ◽  
Non Hodgkin Lymphoma

Tonsillar malignancy is the underlying etiology of only a very small percentage of paediatric unilateral tonsillar enlargements. Further, because of rarity of tonsillar malignancy in children, the diagnosis may be delayed. Authors describe a large bleeding tonsillar mass in a child who remained undiagnosed for two months but finally diagnosed with non-Hodgkin lymphoma at the institution.

scholarly journals Primary splenic lymphoma. Case study

2021 ◽  
Vol 2 (6) ◽  
pp. 6-9
Author(s):  
Leonid I. Dvoretsky ◽  
◽  
Oleg E. Lutsevich ◽  
Vasilii V. Filippov ◽  
Sergei S. Golubev ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Splenic Abscess ◽  
Non Hodgkin Lymphoma ◽  
Splenic Lymphoma ◽  
Asymptomatic Stage ◽  
Primary Splenic Lymphoma

The case of primary splenic lymphoma, the uncommon type of non-Hodgkin lymphoma presenting with prominent splenomegaly, is reported. The disease is characterized by long asymptomatic stage and splenic abscess found during splenectomy.

scholarly journals Effects of FR-91 on Immune Cells from Healthy Individuals and from Patients with Non-Hodgkin Lymphoma

2009 ◽  
Vol 2009 ◽  
pp. 1-9 ◽  
Author(s):  
V. R. M. Lombardi ◽  
E. Martínez ◽  
R. Chacón ◽  
I. Etcheverría ◽  
R. Cacabelos
Keyword(s):  
Immune System ◽  
Hodgkin Lymphoma ◽  
Mononuclear Cells ◽  
Cytokine Production ◽  
Lymphocyte Activation ◽  
Dependent Manner ◽  
Healthy Individuals ◽  
Peripheral Blood Mononuclear ◽  
Non Hodgkin Lymphoma

The immune system is subject to destruction and dysfunction as a result of attacks by pathogenic and environmental agents. In addition, many clinical situations exist in which it is desirable to stimulate or suppress the immune system. The present study evaluated the screening efficacy of flow cytometric lymphocyte subset typing in peripheral blood mononuclear cells from healthy individuals (HI) and from patients with non-Hodgkin lymphoma (NHL) treated with different concentrations of FR-91, a standardized lysate of microbial cells belonging to the Bacillus genus, andin vitrocytokine production. Increased expression of subset markers (CD3, CD4, CD8) in NHL and CD3 in HI suggests an immunomodulating effect of FR-91. In addition the results of cytokine production also demonstrated a clear effect of FR-91 on both populations. A significant increase of IL-6, IL-12, IFN-γand TNF-αwas observed in the HI group after treatment with FR-91. In a similar manner an increase of IL-2, IL-6, IL-12, IFN-γand TNF-αwas also observed in the NHL group. In conclusion FR-91 seems to affect lymphocyte subpopulations,in vitrocytokine production, as well as mitogen-induced lymphocyte activation in a dose-dependent manner in both healthy individuals and NHL patients.

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