Primary splenic lymphoma. Case study

The case of primary splenic lymphoma, the uncommon type of non-Hodgkin lymphoma presenting with prominent splenomegaly, is reported. The disease is characterized by long asymptomatic stage and splenic abscess found during splenectomy.

Management of primary lymphoma of the spleen in a patient with HIV-AIDS: Case report

Primary splenic lymphomas involve the spleen and/or its lymph nodes. They represent <1% of lymphomas and they imply a diagnostic challenge due to its poor symptomatology and low prevalence. There for, the objects this work describe the management and evolution of a patient with HIVAIDS and presentation of a primary lymphoma of the spleen. In this report we present the case of a 52-year-old male patient with HIV infection without treatment presented with abdominal pain, fever and a 2-month weight loss. The pre-operative computed tomography showed splenomegaly and hypodense lesions suspected to be tumoral. He was operated on, performing an exploratory laparotomy, performing an splenectomy. The histopathological study reported a non-Hodgkin lymphoma. Primary splenic lymphoma is a non frequent entity. It is necessary to be acquainted with it in order to suspect it.

PRIMARY SPLENIC LYMPHOMA: CAN TRUCUT BIOPSY AND R-CHOP SUPERSEDE SPLENECTOMY?

Primary Splenic lymphoma is a rare type of Non Hodgkin’s lymphoma of the spleen with or without splenic hilar lymph nodes with preservation of other organ systems. In this case, we encountered a patient who presented with fever of unknown origin since 25 days and was diagnosed with Primary splenic lymphoma based on a tru cut biopsy which was then confirmed by immunohistochemistry. Patient was treated with Chemotherapy alone and showed no recurrence after 6 months of follow up. The aim of reporting this case is to have a high index of suspicion for rare malignancies like PSL in cases of FUO. Contrary to the current guidelines, use of trucut biopsy can be used as a promising investigation to diagnose PSL and treatment with chemotherapy with R-CHOP regimen alone prevented recurrence of the tumour. Investigations like PET-CT which have 100% accuracy in diagnosing PSL can reduce the number of operative procedures like splenectomy used for its diagnosis and treatment.