scholarly journals Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies

Blood ◽  
2014 ◽  
Vol 123 (5) ◽  
pp. 678-686 ◽  
Author(s):  
Holbrook E. Kohrt ◽  
Ariane Thielens ◽  
Aurelien Marabelle ◽  
Idit Sagiv-Barfi ◽  
Caroline Sola ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Mhc Class I ◽  
Nk Cell ◽  
Class I ◽  
Lymphoma Cells ◽  
Killer Cells ◽  
Key Points ◽  
Anti Cd20 ◽  
Cd20 Antibodies

Key Points Blockade of inhibitory KIRs with MHC class I antigens on lymphoma cells by anti-KIR antibodies augments NK-cell spontaneous cytotoxicity. In combination with anti-CD20 mAbs, anti-KIR induces enhanced NK cell–mediated, rituximab-dependent cytotoxicity against lymphoma.

Human Natural Killer Cells Account for Non-MHC Class I-Restricted Cytolysis of Porcine Cells

1997 ◽  
Vol 175 (2) ◽  
pp. 171-178 ◽  
Author(s):  
Caroline E. Donnelly ◽  
Christopher Yatko ◽  
Eric W. Johnson ◽  
Albert S.B. Edge
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Mhc Class I ◽  
Class I ◽  
Killer Cells ◽  
Human Natural Killer Cells

Engagement of MHC Class I Proteins on Natural Killer Cells Inhibits their Killing Capacity

1995 ◽  
Vol 42 (1) ◽  
pp. 34-38 ◽  
Author(s):  
M. G. E. PETERSSON ◽  
A. GRONBERG ◽  
R. KIESSLING ◽  
M. T. FERM
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Mhc Class I ◽  
Class I ◽  
Killer Cells

MHC Class I–Related Chain A Conjugated to Antitumor Antibodies Can Sensitize Tumor Cells to Specific Lysis by Natural Killer Cells

2005 ◽  
Vol 11 (20) ◽  
pp. 7516-7522 ◽  
Author(s):  
Claire Germain ◽  
Christel Larbouret ◽  
Valérie Cesson ◽  
Alena Donda ◽  
Werner Held ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Tumor Cells ◽  
Mhc Class I ◽  
Class I ◽  
Specific Lysis ◽  
Killer Cells ◽  
Antitumor Antibodies

scholarly journals Fewer circulating natural killer cells 28 days after double cord blood transplantation predicts inferior survival and IL-15 response

2016 ◽  
Vol 1 (3) ◽  
pp. 208-218 ◽  
Author(s):  
Rachel J. Bergerson ◽  
Robin Williams ◽  
Hongbo Wang ◽  
Ryan Shanley ◽  
Gretchen Colbenson ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Cord Blood ◽  
Nk Cells ◽  
Natural Killer ◽  
Nk Cell ◽  
Cord Blood Transplantation ◽  
Killer Cells ◽  
Cell Numbers ◽  
Blood Transplantation ◽  
Key Points

Key Points Low numbers of reconstituting NK cells at D+28 after dUCBT are associated with inferior DFS. Patients with low NK cell numbers at D+28 have reduced phosphorylation of STAT5 upon IL-15 stimulation and less Eomes expression.

Donor Lymphocyte–Derived Natural Killer Cells Control MHC Class I–Negative Melanoma

2020 ◽  
Vol 8 (6) ◽  
pp. 756-768 ◽  
Author(s):  
Nana Dang ◽  
Yuan Lin ◽  
Mark Waer ◽  
Ben Sprangers
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Mhc Class I ◽  
Class I ◽  
Killer Cells

scholarly journals Adaptations of Natural Killer Cells to Self-MHC Class I

2014 ◽  
Vol 5 ◽  
Author(s):  
Stéphanie Bessoles ◽  
Camille Grandclément ◽  
Elisenda Alari-Pahissa ◽  
Jasmine Gehrig ◽  
Beena Jeevan-Raj ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Mhc Class I ◽  
Class I ◽  
Killer Cells
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