Fatal Transfusion Malaria

Abstract This report of fatal falciparum malaria emphasizes an unusual but potentially hazardous complication of blood transfusion. To our knowledge this is the first instance of fatal Plasmodium falciparum infection transmitted by this means. The source of infection was an asymptomatic donor who had resided outside an endemic area for more than 30 months. This is the longest interval thus far recorded that falciparum malaria has remained latent before transmission by transfusion.

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Fulminant Plasmodium falciparum Infection Treated With Exchange Blood Transfusion

JAMA ◽

10.1001/jama.1983.03330260062034 ◽

1983 ◽

Vol 249 (2) ◽

pp. 244 ◽

Cited By ~ 30

Author(s):

Sandra L. Kramer

Keyword(s):

Plasmodium Falciparum ◽

Blood Transfusion ◽

Falciparum Infection ◽

Exchange Blood Transfusion ◽

Plasmodium Falciparum Infection

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Delayed clinical presentation of Plasmodium falciparum malaria after leaving an endemic area: a tale of two patients

Journal of Travel Medicine ◽

10.1093/jtm/taaa092 ◽

2020 ◽

Vol 27 (6) ◽

Author(s):

Kaylin Pennington ◽

Samuel T Ives ◽

Anne E P Frosch ◽

Megan K Shaughnessy

Keyword(s):

Plasmodium Falciparum ◽

Falciparum Malaria ◽

Incubation Period ◽

Endemic Area ◽

Clinical Presentation ◽

Plasmodium Falciparum Malaria ◽

International Airport ◽

Source Of Infection ◽

One Year

Malaria due to Plasmodium falciparum (Pf) may be missed if patients present with symptoms outside of the expected incubation period. We describe two patients who developed Pf malaria more than one year after visiting malaria-endemic countries. Both worked at an international airport, but no source of infection was identified.

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Parasite-specific lactate dehydrogenase for the diagnosis of Plasmodium falciparum infection in an endemic area in West Uganda

Tropical Medicine & International Health ◽

10.1111/j.1365-3156.1996.tb00031.x ◽

2007 ◽

Vol 1 (2) ◽

pp. 227-230 ◽

Cited By ~ 10

Author(s):

T. Jelinek ◽

A. H. D. Kilian ◽

M. Henk ◽

E. B. Mughusu ◽

H. D. Nothdurft ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Lactate Dehydrogenase ◽

Endemic Area ◽

Falciparum Infection ◽

Plasmodium Falciparum Infection

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Treatment Outcome Analysis of Artemisinin based Therapy in Plasmodium falciparum Infection: An Observational Study

Biomedical & Pharmacology Journal ◽

10.13005/bpj/1558 ◽

2018 ◽

Vol 11 (4) ◽

pp. 1857-1863

Author(s):

D. Amita Priya ◽

K. Meena Kumari ◽

Muralidhar Varma ◽

V. Amberkar Mohanbabu ◽

Shalini Adiga ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Renal Function ◽

Combination Therapy ◽

Observational Study ◽

Falciparum Malaria ◽

Blood Count ◽

Falciparum Infection ◽

Plasmodium Falciparum Infection ◽

Function Tests ◽

Renal Function Tests

Currently, the preferred treatment for chloroquine (CQ) resistant Plasmodium falciparum (Pf) is Artemisinin combination therapy (ACT). Our aim was to assess the artemisinin based treatment outcomes in patients with Plasmodium falciparum infection. Patients with falciparum infection from a tertiary health care centre in South India were enrolled in this study. It was a non-randomised observational study .The data regarding peripheral blood smear, complete blood count, liver, renal function tests and the treatment given was documented at admission and on the day of discharge. Patients with uncomplicated falciparum malaria were most common. Artesunate and doxycycline was the most common combination used at our centre (54.6%) followed by artemether –lumefantrine. All patients had peripheral smear negative for Plasmodium falciparum parasite by the end of treatment. There was improvement in blood count,liver and renal function tests. Artemisinin based combination therapy was effective in treatment of falciparum malaria.

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