Association between 4-metre gait speed and isometric knee extension muscle strength in patients with interstitial lung disease

Author(s):  
Kenji Nemoto ◽  
Shuji Oh-Ishi ◽  
Yuki Yabuuchi ◽  
Mizu Nonaka ◽  
Hitomi Goto ◽  
...  
Physiotherapy ◽  
2016 ◽  
Vol 102 (3) ◽  
pp. 249-255 ◽  
Author(s):  
Leona Dowman ◽  
Christine F. McDonald ◽  
Catherine J. Hill ◽  
Annemarie Lee ◽  
Kathryn Barker ◽  
...  

2017 ◽  
Vol 7 (3) ◽  
pp. 454-462 ◽  
Author(s):  
Akito Tsugawa ◽  
Yusuke Ogawa ◽  
Naoto Takenoshita ◽  
Yoshitsugu Kaneko ◽  
Hirokuni Hatanaka ◽  
...  

Background/Aims: Diabetes-related dementia (DrD), a dementia subgroup associated with specific diabetes mellitus (DM)-related metabolic abnormalities, is clinically and pathophysiologically different from Alzheimer disease (AD) and vascular dementia. We determined whether skeletal muscle strength, quality, and mass decrease in individuals with DrD. Methods: We evaluated grip and knee extension strength, muscle mass, and gait speed in 106 patients with probable AD and without type 2 DM (AD[–DM] group), 74 patients with probable AD and with DM (AD[+DM] group), and 36 patients with DrD (DrD group). Muscle quality was defined as the ratio of muscle strength to muscle mass. Results: Both female and male subjects with DrD showed significantly decreased muscle strength and quality in the upper extremities compared with the subjects with AD[–DM] or AD[+DM]. Female subjects with DrD showed significantly decreased muscle quality in the lower extremities compared with the subjects with AD[–DM]. Both female and male subjects with DrD had a significantly lower gait speed compared with the subjects with AD[–DM]. However, there were no significant differences in muscle mass and the prevalence of sarcopenia between the groups. Conclusion: Subjects with DrD showed decreased muscle strength and quality, but not muscle mass, and had a low gait speed.


2019 ◽  
Vol 75 (10) ◽  
pp. 1996-2002
Author(s):  
Kaisa Koivunen ◽  
Elina Sillanpää ◽  
Mikaela von Bonsdorff ◽  
Ritva Sakari ◽  
Timo Törmäkangas ◽  
...  

Abstract Background Physiological reserve, as indicated by muscle strength and gait speed, may be especially determinant of survival in people who are exposed to a health stressor. We studied whether the association between strength/speed and mortality risk would be stronger in the time period after a fracture compared to other time periods. Methods Participants were population-based sample of 157 men and 325 women aged 75 and 80 years at baseline. Maximal 10-m gait speed and maximal isometric grip and knee extension strength were tested at the baseline before the fracture. Subsequent fracture incidence and mortality were followed up for 15 years. Cox regression analysis was used to estimate fracture time-stratified effects of gait speed and muscle strength on mortality risk in three states: (i) nonfracture state, (ii) the first postfracture year, and (iii) after the first postfracture year until death/end of follow-up. Results During the follow-up, 20% of the men and 44% of the women sustained a fracture. In both sexes, lower gait speed and in women lower knee extension strength was associated with increased mortality risk in the nonfracture state. During the first postfracture year, the mortality risk associated with slower gait and lower strength was increased and higher than in the nonfracture state. After the first postfracture year, mortality risk associated with lower gait speed and muscle strength attenuated. Conclusions Lower gait speed and muscle strength were more strongly associated with mortality risk after fracture than during nonfracture time, which may indicate decreased likelihood of recovery.


Sign in / Sign up

Export Citation Format

Share Document