scholarly journals Pulmonary vascular and cardiac impairment in interstitial lung disease

2017 ◽  
Vol 26 (143) ◽  
pp. 160053 ◽  
Author(s):  
Marios Panagiotou ◽  
Alistair C. Church ◽  
Martin K. Johnson ◽  
Andrew J. Peacock
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Interstitial Lung Disease ◽  
Natural History ◽  
Lung Disease ◽  
Pulmonary Vascular Resistance ◽  
Right Heart Failure ◽  
Right Heart ◽  
History Of ◽  
Adverse Factor

Pulmonary vascular and cardiac impairment is increasingly appreciated as a major adverse factor in the natural history of interstitial lung disease. This clinically orientated review focuses on the current concepts in the pathogenesis, pathophysiology and implications of the detrimental sequence of increased pulmonary vascular resistance, pre-capillary pulmonary hypertension and right heart failure in interstitial lung disease, and provides guidance on its management.

scholarly journals An atypical assessment of Ebstein’s anomaly in an 86-year-old man

2015 ◽  
Vol 76 (2) ◽  
Author(s):  
Antonello D’Andrea ◽  
Giancarlo Scognamiglio ◽  
Franco Giordano ◽  
Sergio Cuomo ◽  
Maria Giovanna Russo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Natural History ◽  
Supraventricular Tachycardia ◽  
Right Heart Failure ◽  
Right Atrial ◽  
Ebstein’S Anomaly ◽  
Congenital Disease ◽  
Right Heart ◽  
Ebstein's Anomaly ◽  
History Of

We present the echocardiographic analysis of an 86- year-old man affected by Ebstein’s anomaly. In the natural history of this congenital disease only 5% of patients survive beyond the fifth decade. The patient presented severe right atrial dilatation and right heart failure, and he was referred to our institution for supraventricular tachycardia.

scholarly journals Echocardiographic Assessment of Ebstein's Anomaly in a 60-Year-Old Man

2009 ◽  
Vol 2009 ◽  
pp. 1-2 ◽  
Author(s):  
Elisabetta Palmerini ◽  
Duccio Federici ◽  
Alessia Del Pasqua ◽  
Sonia Bernazzali ◽  
Matteo Lisi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Natural History ◽  
Right Heart Failure ◽  
Ebstein’S Anomaly ◽  
Congenital Disease ◽  
Right Heart ◽  
Ebstein's Anomaly ◽  
Echocardiographic Evaluation ◽  
History Of ◽  
Echocardiographic Assessment

We present an echocardiographic evaluation of an elderly man affected with Ebstein's anomaly. In the natural history of this congenital disease only 5% of patients survive beyond the fifth decade. The patient presented severe right heart failure and he was refered to our institution for heart transplantation.

Inhibition of mTOR by rapamycin does not improve hypoxic pulmonary hypertension-induced right heart failure in old mice

2021 ◽  
pp. 111395
Author(s):  
Benjamin D. McNair ◽  
Jacob A. Schlatter ◽  
Ross F. Cook ◽  
Musharraf Yusifova ◽  
Danielle R. Bruns
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Right Heart Failure ◽  
Right Heart ◽  
Hypoxic Pulmonary Hypertension ◽  
Old Mice

scholarly journals Genistein, a Soy Phytoestrogen, Reverses Severe Pulmonary Hypertension and Prevents Right Heart Failure in Rats

Hypertension ◽  
2012 ◽  
Vol 60 (2) ◽  
pp. 425-430 ◽  
Author(s):  
Humann Matori ◽  
Soban Umar ◽  
Rangarajan D. Nadadur ◽  
Salil Sharma ◽  
Rod Partow-Navid ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Right Heart Failure ◽  
Severe Pulmonary Hypertension ◽  
Right Heart

Pulmonary Hypertension Associated With Myocardial Amyloid Degeneration: a Case Report

2021 ◽  
Author(s):  
Lu Yan ◽  
Qixian Zeng ◽  
Changming Xiong ◽  
Zhihui Zhao ◽  
Qing Zhao ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Blood Vessels ◽  
Amyloid Fibrils ◽  
Right Heart Failure ◽  
Pulmonary Artery Hypertension ◽  
Pulmonary Vasculature ◽  
Vascular Involvement ◽  
Right Heart ◽  
Protein Deposits

Abstract Background: There is very little literature on Pulmonary hypertension associated with myocardial amyloid degeneration. At present, only 10 cases pulmonary hypertension cased by amyloid protein deposits in the pulmonary blood vessels have been reported by Eder et al. We reported a case that the patient was pulmonary artery hypertension combined with myocardial amyloid change. It’s aim to claims that pulmonary hypertension is most likely caused by amyloid fibrin deposition in pulmonary blood vessels.Case presentation: We report a case of a 65-year-old male patient with with AL and ATTR combined type amyloidosis who developed right heart failure because of severe pulmonary hypertension. Pulmonary hypertension due to deposition of amyloid in the pulmonary vasculature is an uncommon finding; however, it should be considered in cases of unexplained pulmonary hypertension in patients with amyloidosis.Conclusion: we present a men with amyloidosis who developed dyspnea and right heart failure and was diagnosed with pulmonary hypertension, most probably secondary to pulmonary vascular involvement by amyloid fibrils.

Efficacy and safety of a calcium sensitizer, levosimendan, in patients with right heart failure due to pulmonary hypertension

2017 ◽  
Vol 12 (4) ◽  
pp. 1518-1525 ◽  
Author(s):  
Rong Jiang ◽  
Qin‐Hua Zhao ◽  
Wen‐Hui Wu ◽  
Rui Zhang ◽  
Ping Yuan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Right Heart Failure ◽  
Efficacy And Safety ◽  
Right Heart ◽  
Calcium Sensitizer

scholarly journals Critical Care Management of Decompensated Right Heart Failure in Pulmonary Arterial Hypertension Patients – An Ongoing Approach

2021 ◽  
Vol 7 (3) ◽  
pp. 170-183
Author(s):  
Ioan Tilea ◽  
Andreea Varga ◽  
Anca-Meda Georgescu ◽  
Bianca-Liana Grigorescu
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Intensive Care ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Care Management ◽  
Right Heart Failure ◽  
Right Heart ◽  
Continuous Increase ◽  
Pulmonary Arterial

Abstract Despite substantial advancements in diagnosis and specific medical therapy in pulmonary arterial hypertension patients’ management, this condition continues to represent a major cause of mortality worldwide. In pulmonary arterial hypertension, the continuous increase of pulmonary vascular resistance and rapid development of right heart failure determine a poor prognosis. Against targeted therapy, patients inexorable deteriorate over time. Pulmonary arterial hypertension patients with acute right heart failure who need intensive care unit admission present a complexity of the disease pathophysiology. Intensive care management challenges are multifaceted. Awareness of algorithms of right-sided heart failure monitoring in intensive care units, targeted pulmonary hypertension therapies, and recognition of precipitating factors, hemodynamic instability and progressive multisystem organ failure requires a multidisciplinary pulmonary hypertension team. This paper summarizes the management strategies of acute right-sided heart failure in pulmonary arterial hypertension adult cases based on recently available data.

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